Outbreak of hepatitis C virus infection in hemodialysis unit

Bengü Tatar; Şükran Köse; Murat Sayan

doi:10.17941/agd.662463

Outbreak of hepatitis C virus infection in hemodialysis unit

Öz

Background and Aim: Hepatitis C virus transmission continues to be a significant public health concern in patients undergoing hemodialysis and occasionally causes outbreaks despite risk reduction after the anti-HCV screening. This study aimed to investigate an outbreak of hepatitis C virus in the hemodialysis unit to identify the infection source and underline lapses in the infection control practices. Material and Methods: Patients and staff were assessed for hepatitis C virus infection after the outbreak. All anti‐HCV-positive patients were tested for genotype or subtypes by performing a phylogenetic analysis of NS3 sequences. The current infection control applications and possible risk factors in the unit were examined to determine the source of infection. Results: Overall, 115 patients, including three patients who were followed up for chronic hepatitis C infection, were evaluated. Anti‐HCV seroconversion was detected in 10 new patients. All patients were in the same room and during the same shift. Several lapses in infection control practices were observed. Phylogenetic analysis showed that the outbreak was caused by the same viral strain. Notably, all patients were infected with genotype 1a, and mutations in the NS3 region, subgenotype, and drug resistance were identical to one of the three patients with chronic hepatitis C. Conclusion: Direct observation and molecular test results indicated a transmission from patient to patient, thereby highlighting the importance of infection control.

Anahtar Kelimeler

hepatitis C virus,outbreak,hemodialysis

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Bengü Tatar
0000-0003-3787-1734
Türkiye

Şükran Köse Bu kişi benim
0000-0002-4228-1213
Türkiye

Murat Sayan Bu kişi benim
0000-0002-4374-7193
Türkiye

Yayımlanma Tarihi

25 Aralık 2019

Gönderilme Tarihi

20 Ağustos 2019

Kabul Tarihi

11 Aralık 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 18 Sayı: 3

DOI

https://doi.org/10.17941/agd.662463

IZ

https://izlik.org/JA29AD24ES

Kaynak Göster

RIS / Bibtex

APA

Tatar, B., Köse, Ş., & Sayan, M. (2019). Outbreak of hepatitis C virus infection in hemodialysis unit. Akademik Gastroenteroloji Dergisi, 18(3), 91-94. https://doi.org/10.17941/agd.662463

AMA

1.Tatar B, Köse Ş, Sayan M. Outbreak of hepatitis C virus infection in hemodialysis unit. Akademik Gastroenteroloji Dergisi. 2019;18(3):91-94. doi:10.17941/agd.662463

Chicago

Tatar, Bengü, Şükran Köse, ve Murat Sayan. 2019. “Outbreak of hepatitis C virus infection in hemodialysis unit”. Akademik Gastroenteroloji Dergisi 18 (3): 91-94. https://doi.org/10.17941/agd.662463.

EndNote

Tatar B, Köse Ş, Sayan M (01 Aralık 2019) Outbreak of hepatitis C virus infection in hemodialysis unit. Akademik Gastroenteroloji Dergisi 18 3 91–94.

IEEE

[1]B. Tatar, Ş. Köse, ve M. Sayan, “Outbreak of hepatitis C virus infection in hemodialysis unit”, Akademik Gastroenteroloji Dergisi, c. 18, sy 3, ss. 91–94, Ara. 2019, doi: 10.17941/agd.662463.

ISNAD

Tatar, Bengü - Köse, Şükran - Sayan, Murat. “Outbreak of hepatitis C virus infection in hemodialysis unit”. Akademik Gastroenteroloji Dergisi 18/3 (01 Aralık 2019): 91-94. https://doi.org/10.17941/agd.662463.

JAMA

1.Tatar B, Köse Ş, Sayan M. Outbreak of hepatitis C virus infection in hemodialysis unit. Akademik Gastroenteroloji Dergisi. 2019;18:91–94.

MLA

Tatar, Bengü, vd. “Outbreak of hepatitis C virus infection in hemodialysis unit”. Akademik Gastroenteroloji Dergisi, c. 18, sy 3, Aralık 2019, ss. 91-94, doi:10.17941/agd.662463.

Vancouver

1.Bengü Tatar, Şükran Köse, Murat Sayan. Outbreak of hepatitis C virus infection in hemodialysis unit. Akademik Gastroenteroloji Dergisi. 01 Aralık 2019;18(3):91-4. doi:10.17941/agd.662463