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Gastrointestinal endoscopy findings in iron-deficient patients

Year 2012, Volume: 11 Issue: 3, 113 - 116, 01.12.2012

Abstract

Background and Aims: Diseases of the gastrointestinal tract are among the important causes of iron deficiency. Our aim was to identify upper and lower gastrointestinal endoscopic findings in patients with iron deficiency. Materials and Methods: Patients diagnosed with iron deficiency according to the ICD-10 coding system and who underwent upper and/or lower gastrointestinal system endoscopy were included in the study. Endoscopic and pathologic findings were collected for descriptive statistics. Results:Data of 1200 patients were reviewed. Two hundred and seven patients were included in the study. Upper and lower gastrointestinal endoscopy were performed in 205 and 169 patients, respectively. In upper gastrointestinal endoscopy, biopsies were taken from the stomach and second part of the duodenum in 116 and 84 patients, respectively. In lower gastrointestinal endoscopy, 30% of patients had no pathologic finding, whereas 4.7% of patients were diagnosed with colorectal cancer. Conclusions: Iron deficiency is an important finding in gastrointestinal diseases. Upper and lower endoscopic examination is vital for explaining the cause of iron deficiency.

References

  • Looker AC, Dallman PR, Carroll MD, et al. Prevalence of iron deficiency in the United States. JAMA 1997;277:973-6.
  • DeMaeyer E, Adiels-Tegman M. The prevalence of anaemia in the world. World Health Stat Q. [Comparative Study]. 1985;38:302-16.
  • McIntyre AS, Long RG. Prospective survey of investigations in outpatients referred with iron deficiency anaemia. Gut 1993;34:1102-7.
  • Rockey DC, Cello JP. Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia. N Engl J Med 1993;329:1691-5.
  • Kepczyk T, Kadakia SC. Prospective evaluation of gastrointestinal tract in patients with iron-deficiency anemia. Dig Dis Sci 1995;40:1283-9.
  • Cook IJ, Pavli P, Riley JW, et al. Gastrointestinal investigation of iron deficiency anaemia. Br Med J 1986;292:1380-2.
  • Hardwick RH, Armstrong CP. Synchronous upper and lower gastrointestinal endoscopy is an effective method of investigating iron-deficiency anaemia. Br J Surg 1997;84:1725-8.
  • Niv E, Elis A, Zissin R, et al. Iron deficiency anemia in patients without gastrointestinal symptoms--a prospective study. Fam Pract 2005;22:58-61.
  • Ho CH, Chau WK, Hsu HC, et al. Predictive risk factors and prevalence of malignancy in patients with iron deficiency anemia in Taiwan. Am J Hematol 2005;78:108-12.
  • James MW, Chen CM, Goddard WP, et al. Risk factors for gastrointestinal malignancy in patients with iron-deficiency anaemia. Eur J Gastroenterol Hepatol 2005;17:1197-203.
  • Ioannou GN, Rockey DC, Bryson CL, et al. Iron deficiency and gastrointestinal malignancy: a population-based cohort study. Am J Med 2002;113:276-80.
  • Majid S, Salih M, Wasaya R, Jafri M. Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms. BMC Gastroenterol 2008;8:52.
  • Patterson RN, Johnston SD. Iron deficiency anaemia: are the British Society of Gastroenterology guidelines being adhered to? Postgrad Med J 2003;79:226-8.
  • Goddard AF, McIntyre AS, Scott BB. Guidelines for the management of iron deficiency anaemia. British Society of Gastroenterology. Gut 2000;46 Suppl 3-4:IV1-IV5.
  • Hopper AD, Leeds JS, Hurlstone DP, et al. Are lower gastrointestinal investigations necessary in patients with coeliac disease? Eur J Gastroenterol Hepatol 2005;17:617-21.
  • Emami MH, Karimi S, Kouhestani S. Is routine duodenal biopsy necessary for the detection of celiac disease in patients presenting with iron deficiency anemia? Int J Prev Med 2012;3:273-7.
  • Pacifico L, Anania C, Osborn JF, et al. Consequences of Helicobacter pylori infection in children. World J Gastroenterol 2010;16:5181-94.
  • Cardenas VM, Prieto-Jimenez CA, Mulla ZD, et al. Helicobacter pylori eradication and change in markers of iron stores among non-iron-deficient children in El Paso, Texas: an etiologic intervention study. J Pediatr Gastroenterol Nutr 2011;52:326-32.
  • Capurso G, Baccini F, Osborn J, et al. Can patient characteristics predict the outcome of endoscopic evaluation of iron deficiency anemia: a multiple logistic regression analysis. Gastrointest Endosc 2004;59:766-71.

Demir eksikliği olan hastalarda gastrointestinal sistem endoskopi bulguları

Year 2012, Volume: 11 Issue: 3, 113 - 116, 01.12.2012

Abstract

Giriş ve Amaç:Gastrointestinal sistem hastalıkları demir esikliğinin önemli nedenlerinden biridir. Biz bu çalıflma ile demir eksikliği olan hastalardaki üst ve alt gastrointestinal endoskopi bulgularını tanımlamayı amaçladık.Gereç ve Yöntem: ICD-10 kodlama sistemine göre demir eksikliği tanısı almıfl hastaların bulguları retrospektif olarak tarandı. Üst ve alt gastrointestinal endoskopi bulguları ile varsa biyopsi sonuçları toplanarak tanımlayıcı istatistik ile değerlendirildi. Bulgular:Çalıflma için, ICD-10'a göre demir eksikliği tanısı almıfl 1200 hastanın verileri gözden geçirildi. Değerlendirmeye alınan 207 hastanın 205'ine üst gastrointestinal endoskopi yapılmıfl ve 116 hastadan mide, 84 hastadan duodenal biyopsi alınmıfltı. Kolonoskopi yapılan 169 hastanın %30'unda herhangi bir patoloji saptanmazken, %4.7'sinde kolorektal kanser saptandı.Sonuç: Demir eksikliği gastrointestinal sistem patolojilerinin önemli bir bulgusudur. Üst ve alt gastrointestinal endoskopi bu bulguyu ortaya çıkaran nedenleri arafltırmada önemli ve gerekli tanı yöntemleridir.

References

  • Looker AC, Dallman PR, Carroll MD, et al. Prevalence of iron deficiency in the United States. JAMA 1997;277:973-6.
  • DeMaeyer E, Adiels-Tegman M. The prevalence of anaemia in the world. World Health Stat Q. [Comparative Study]. 1985;38:302-16.
  • McIntyre AS, Long RG. Prospective survey of investigations in outpatients referred with iron deficiency anaemia. Gut 1993;34:1102-7.
  • Rockey DC, Cello JP. Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia. N Engl J Med 1993;329:1691-5.
  • Kepczyk T, Kadakia SC. Prospective evaluation of gastrointestinal tract in patients with iron-deficiency anemia. Dig Dis Sci 1995;40:1283-9.
  • Cook IJ, Pavli P, Riley JW, et al. Gastrointestinal investigation of iron deficiency anaemia. Br Med J 1986;292:1380-2.
  • Hardwick RH, Armstrong CP. Synchronous upper and lower gastrointestinal endoscopy is an effective method of investigating iron-deficiency anaemia. Br J Surg 1997;84:1725-8.
  • Niv E, Elis A, Zissin R, et al. Iron deficiency anemia in patients without gastrointestinal symptoms--a prospective study. Fam Pract 2005;22:58-61.
  • Ho CH, Chau WK, Hsu HC, et al. Predictive risk factors and prevalence of malignancy in patients with iron deficiency anemia in Taiwan. Am J Hematol 2005;78:108-12.
  • James MW, Chen CM, Goddard WP, et al. Risk factors for gastrointestinal malignancy in patients with iron-deficiency anaemia. Eur J Gastroenterol Hepatol 2005;17:1197-203.
  • Ioannou GN, Rockey DC, Bryson CL, et al. Iron deficiency and gastrointestinal malignancy: a population-based cohort study. Am J Med 2002;113:276-80.
  • Majid S, Salih M, Wasaya R, Jafri M. Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms. BMC Gastroenterol 2008;8:52.
  • Patterson RN, Johnston SD. Iron deficiency anaemia: are the British Society of Gastroenterology guidelines being adhered to? Postgrad Med J 2003;79:226-8.
  • Goddard AF, McIntyre AS, Scott BB. Guidelines for the management of iron deficiency anaemia. British Society of Gastroenterology. Gut 2000;46 Suppl 3-4:IV1-IV5.
  • Hopper AD, Leeds JS, Hurlstone DP, et al. Are lower gastrointestinal investigations necessary in patients with coeliac disease? Eur J Gastroenterol Hepatol 2005;17:617-21.
  • Emami MH, Karimi S, Kouhestani S. Is routine duodenal biopsy necessary for the detection of celiac disease in patients presenting with iron deficiency anemia? Int J Prev Med 2012;3:273-7.
  • Pacifico L, Anania C, Osborn JF, et al. Consequences of Helicobacter pylori infection in children. World J Gastroenterol 2010;16:5181-94.
  • Cardenas VM, Prieto-Jimenez CA, Mulla ZD, et al. Helicobacter pylori eradication and change in markers of iron stores among non-iron-deficient children in El Paso, Texas: an etiologic intervention study. J Pediatr Gastroenterol Nutr 2011;52:326-32.
  • Capurso G, Baccini F, Osborn J, et al. Can patient characteristics predict the outcome of endoscopic evaluation of iron deficiency anemia: a multiple logistic regression analysis. Gastrointest Endosc 2004;59:766-71.
There are 19 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Hakan Ümit Ünal - This is me

Cihan Fidan This is me

Murat Korkmaz - This is me

Haldun Selçuk This is me

Publication Date December 1, 2012
Published in Issue Year 2012 Volume: 11 Issue: 3

Cite

APA -, H. Ü. Ü., Fidan, C., -, M. K., Selçuk, H. (2012). Demir eksikliği olan hastalarda gastrointestinal sistem endoskopi bulguları. Akademik Gastroenteroloji Dergisi, 11(3), 113-116.

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