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Upper gastrointestinal lesions in portal hypertension

Year 2011, Volume: 10 Issue: 2, 66 - 69, 01.08.2011

Abstract

: This prospective study was planned to detect the frequency of portal hypertension-related upper gastrointestinal lesions and the relationship between these lesions and the etiology of portal hypertension, bleeding history, Child-Pugh class, and endoscopic variceal treatment. Materials and Methods: A total of 128 patients (45 female) with a mean age of 47.8±15.3 years were included in the study. In these patients, 1) the presence of varices from the esophagus up to the second portion of the duodenum, 2) the presence of peptic disease and 3) the presence of portal hypertensive gastropathy and duodenopathy were investigated. Results: The patients were divided into 4 groups as follows: Group I, patients without bleeding (41 patients); Group II, patients with bleeding but no endoscopic treatment (15 patients); Group III, patients with endoscopic variceal treatment without eradication (41 patients); and Group IV, patients with esophageal variceal eradication (31 patients). While there were no esophageal varices in Group IV, the other 3 groups all had esophageal varices (p

References

  • Papazian A, Braillon A, Dupas JL, et al. Portal hypertensive gastric mucosa: an endoscopic study. Gut 1986; 27: 1199-203.
  • Dobrucal› A, Uzunismail H, Tuncer M, et al. Karaci¤er sirozunda özofagogastroduodenoskopik bulgular ve Helikobakter pilori enfeksiyonu. Endoskopi Dergisi 1995; 6: 9-14.
  • McCormack TT, Sims J, Eyre-Brook I, et al. Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy. Gut 1985; 26: 1226-32.
  • Sarin SK, Jain AK, Lamba GS, et al. Isolated gastric varices: prevalence, clinical relevance and natural history. Dig Surg 2003; 20: 427.
  • Helmy A, Al Kahtani K, Al Fadda M. Updates in the pathogenesis, diagnosis and management of ectopic varices. Hepatol Int 2008; 2: 322-34.
  • Nortan ID, Andrews JC, Kamath PS. Management of ectopic varices. Hepatology 1998; 28: 1154-8.
  • Bahçecio¤lu ‹, Do¤ukan A, Demira¤ K, et al. Karaci¤er sirozunda endoskopik bulgular ve Helikobakter pilori iliflkisi. Endoskopi Dergisi 1997; 8: 108-11.
  • Bayramiçli OU, Kavuncuo¤lu F, Dalay R, et al. Portal hipertansiyonda özofagus varislerine efllik eden üst gastrointestinal sistem lezyonlar›. Endoskopi Dergisi 1997; 8: 117-9.
  • Özdil S, Befl›fl›k F, Boztafl G, et al. Congestive gastropathy and upper endoscopic findings in 250 portal hypertensive patients. Turk J Gastroenterol 1992; 3: 238-40
  • D’Amico G, Montalbano L, Traina M, et al. Natural history of congestive gastropathy in cirrhosis. The Liver Study Group of V. Cervello Hospital. Gastroenterology 1990; 99: 1558-64.
  • Sacchetti C, Capello M, Rebecchi P, et al. Frequency of upper gastrointestinal lesions in patients wih liver cirrhosis. Dig Dis Sci 1988; 33: 1218-22.
  • Menchen L, Ripoll C, Marin-Jimenez I, et al. Prevalence of portal hypertensive duodenopathy in cirrhosis: clinical and haemodyhamic features. Eur J Gastroenterol Hepatol 2006; 18: 649-53.
  • Nagral AS, Joshi AS, Bhatia SJ, et al. Congestive jejunopathy in portal hypertension. Gut 1993; 34: 694-7.
  • Barakat M, Mostafa M, Mahran Z, Soliman AG. Portal hypertensive duodenopathy: clinical, endoscopic and histopathologic profiles. Am J Gastroenterol 2007; 102: 2793-802.
  • Dolar ME, Öztürk M, Gülten M ve ark. Sirotik portal hipertansiyonlu hastalarda üst gastrointestinal sistemde görülen patolojiler. Turk J Gastroenterol 1995; 6: 353-4.
  • Chen JJ, Changchien CS, Tai DI, et al. Role of Helicobacter pylori in cirrhotic patients with peptic ulcer. Dig Dis Sci 1994; 39: 1565-8.
  • Zaman A, Hapke R, Flora K. Prevalence of upper and lower gastrointestinal tract findings in liver transplant candidates undergoing screening endoscopic evaluation. Am J Gastroenterol 1999; 94: 895-9.

Portal hipertansiyonda üst gastrointestinal lezyonlar

Year 2011, Volume: 10 Issue: 2, 66 - 69, 01.08.2011

Abstract

Portal hipertansiyonlu hastalarda üst gastrointestinal sistemde bulunabilecek portal hipertansiyonla ilişkili lezyonların sıklığını saptamak ve bu lezyonların portal hipertansiyon etyolojisi, kanama öyküsü, Child-Pugh sınıfı ve endoskopik tedaviyle ilişkisini araştırmak amaçlarıyla bu prospektif çalışma planlanmıştır. Gereç ve Yöntem: Çalışmamıza ortalama yaşları 47.8±15.3 olan 45'i kadın toplam 128 hasta alındı. Hastalarda, 1) özofagusdan duodenum ikinci kıtasına dek varis olup olmadığı, 2) peptik hastalık varlığı ve 3) portal hipertansif gastropati ile portal hipertansif duodenopati varlığı araştırıldı. Bulgular: Hastalar 4 gruba ayrılarak değerlendirildi. Grup-I kanama geçirmemiş olanlar (41 hasta), Grup-II kanama geçirmiş olup tedavi yapılmamış olanlar (15 hasta), Grup-III tedavi programında olup özofagus varisleri eradike edilmemiş olanlar (41 hasta), Grup-IV özofagus varisleri eradike edilmiş olanlar (31 hasta). Eradikasyon sağlanmış olan Grup-IV'deki hastaların hiçbirinde özofagus varisi bulunmazken, diğer üç gruptaki hastaların hepsinde vardı (p

References

  • Papazian A, Braillon A, Dupas JL, et al. Portal hypertensive gastric mucosa: an endoscopic study. Gut 1986; 27: 1199-203.
  • Dobrucal› A, Uzunismail H, Tuncer M, et al. Karaci¤er sirozunda özofagogastroduodenoskopik bulgular ve Helikobakter pilori enfeksiyonu. Endoskopi Dergisi 1995; 6: 9-14.
  • McCormack TT, Sims J, Eyre-Brook I, et al. Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy. Gut 1985; 26: 1226-32.
  • Sarin SK, Jain AK, Lamba GS, et al. Isolated gastric varices: prevalence, clinical relevance and natural history. Dig Surg 2003; 20: 427.
  • Helmy A, Al Kahtani K, Al Fadda M. Updates in the pathogenesis, diagnosis and management of ectopic varices. Hepatol Int 2008; 2: 322-34.
  • Nortan ID, Andrews JC, Kamath PS. Management of ectopic varices. Hepatology 1998; 28: 1154-8.
  • Bahçecio¤lu ‹, Do¤ukan A, Demira¤ K, et al. Karaci¤er sirozunda endoskopik bulgular ve Helikobakter pilori iliflkisi. Endoskopi Dergisi 1997; 8: 108-11.
  • Bayramiçli OU, Kavuncuo¤lu F, Dalay R, et al. Portal hipertansiyonda özofagus varislerine efllik eden üst gastrointestinal sistem lezyonlar›. Endoskopi Dergisi 1997; 8: 117-9.
  • Özdil S, Befl›fl›k F, Boztafl G, et al. Congestive gastropathy and upper endoscopic findings in 250 portal hypertensive patients. Turk J Gastroenterol 1992; 3: 238-40
  • D’Amico G, Montalbano L, Traina M, et al. Natural history of congestive gastropathy in cirrhosis. The Liver Study Group of V. Cervello Hospital. Gastroenterology 1990; 99: 1558-64.
  • Sacchetti C, Capello M, Rebecchi P, et al. Frequency of upper gastrointestinal lesions in patients wih liver cirrhosis. Dig Dis Sci 1988; 33: 1218-22.
  • Menchen L, Ripoll C, Marin-Jimenez I, et al. Prevalence of portal hypertensive duodenopathy in cirrhosis: clinical and haemodyhamic features. Eur J Gastroenterol Hepatol 2006; 18: 649-53.
  • Nagral AS, Joshi AS, Bhatia SJ, et al. Congestive jejunopathy in portal hypertension. Gut 1993; 34: 694-7.
  • Barakat M, Mostafa M, Mahran Z, Soliman AG. Portal hypertensive duodenopathy: clinical, endoscopic and histopathologic profiles. Am J Gastroenterol 2007; 102: 2793-802.
  • Dolar ME, Öztürk M, Gülten M ve ark. Sirotik portal hipertansiyonlu hastalarda üst gastrointestinal sistemde görülen patolojiler. Turk J Gastroenterol 1995; 6: 353-4.
  • Chen JJ, Changchien CS, Tai DI, et al. Role of Helicobacter pylori in cirrhotic patients with peptic ulcer. Dig Dis Sci 1994; 39: 1565-8.
  • Zaman A, Hapke R, Flora K. Prevalence of upper and lower gastrointestinal tract findings in liver transplant candidates undergoing screening endoscopic evaluation. Am J Gastroenterol 1999; 94: 895-9.
There are 17 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Hüseyin Alkım This is me

Ülkü Dağlı This is me

Canan Alkım This is me

Burhan Şahin This is me

Publication Date August 1, 2011
Published in Issue Year 2011 Volume: 10 Issue: 2

Cite

APA Alkım, H., Dağlı, Ü., Alkım, C., Şahin, B. (2011). Portal hipertansiyonda üst gastrointestinal lezyonlar. Akademik Gastroenteroloji Dergisi, 10(2), 66-69.

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