Alerjik rinitli bir olguda eozinofilik özofajit

Yıl 2018, Cilt: 17 Sayı: 1, 41 - 43, 24.04.2018

Fatma Düşünür Günsen Serhat Bor Murat Sezak Aytül Zerrin Sin

https://doi.org/10.17941/agd.428946

Öz

Eozinofilik özofajit; özofagus mukozasında eozinofilik infiltrasyon ile karakterize kronik, immün aracılı bir tablodur. Erişkinlerde özofageal disfonksiyon semptomları olan disfaji, gıda takılma hissi, regürjitasyon, kusma ve göğüs ağrısı en sık görülen yakınmalardır. Tanı hastanın semptomları eşliğinde endoskopik ve histolojik bulgular ile konur. Bu olguda alerjik riniti ve eozinofilik özofajiti olan bir hasta tanımlanmaktadır

Anahtar Kelimeler

Disfaji, eozinofilik infiltrasyon, alerjik rinit

Allergic rhinitis in eosinophilic esophagitis

Öz

Eosinophilic esophagitis is a chronic, immune-mediated disease that is characterized by eosinophilic infiltration into the esophagus mucosa. In adults, the symptoms of esophageal dysfunction include dysphagia, food bolus impaction, regurgitation, vomiting, and chest pain. The diagnosis of eosinophilic esophagitis should be based on the symptoms, endoscopic appearance of the esophagus mucosa, and histological findings. This case report describes a 23-year-old male with eosinophilic esophagitis and allergic rhinitis.

Anahtar Kelimeler

Dysphagia, eosinophilic infiltration, allergic rhinitis

Kaynakça

• 1. Liacouras CA, Furuta GT, Hirano I, et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol 2011;128:3-20.
• 2. Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol 2004;113:11-28.
• 3. Fox VL, Nurko S, Furuta GT. Eosinophilic esophagitis: it’s not just kid’s stuff. Gastrointest Endosc 2002;56:260-70.
• 4. Prasad GA, Alexander JA, Schleck CD, et al. Epidemiology of eosinophilic esophagitis over three decades in Olmsted County, Minnesota. Clin Gastroenterol Hepatol 2009;7:1055-61.
• 5. Hruz P, Straumann A, Bussmann C, et al; Swiss EoE study group. Escalating incidence of eosinophilic esophagitis: a 20-year prospective, population-based study in Olten County, Switzerland. J Allergy Clin Immunol 2011; 128:1349-50.
• 6. Spergel JM, Andrews T, Brown-Whitehorn TF, et al. Treatment of eosinophilic esophagitis with spesific food elimination diet directed by a combination of skin prick and patch tests. Ann Allergy Asthma Immunol 2005;95:336-43.
• 7. Simon D, Marti H, Heer P, Simon HU, et al. Eosiniphilic esophagitis is frequently associated with IgE-mediated allergic airway diseases. J Allergy Clin Immuno 2005; 115:1090-2.
• 8. Fogg IM, Ruchelli E, Spergel JM. Pollen and eosinophilic esophagitis. J Allergy Clin Immunol 2003;112:796-7.
• 9. Croese J, Fairley SK, Masson JW, et al. Clinical and endoscopic features of eosinophilic esophagitis in adults. Gastrointest Endosc 2003;58:516-22.
• 10. Mackenzie SH, Go M, Chadwick B, et al. Eosinophilic oesophagitis in patients presenting with dysphagia--a prospective analysis. Aliment Pharmacol Ther 2008;28:1140-6.
• 11. Aceves SS, Ackerman SJ. Relationships between eosinophilic inflammation, tissue remodeling, and fibrosis in eosinophilic esophagitis. Immunol Allergy Clin North Am 2009;29:197-211.
• 12. Vazquez-Elizondo G, Ngamruengphong S, Khrisna M, et al. The outcome of patients with oesophageal eosinophilic infiltration after an eight-week trial of a proton pump inhibitor. Aliment Pharmacol Ther 2013;38:1312-9. 13. Arora AS, Perrault J, Smyrk TC. Topical corticosteroid treatment of dysphagia due to eosinophilic esophagitis in adults. Mayo Clin Proc 2003;78:830-5.
• 14. Konikoff MR, Noel RJ, Blanchard C, et al. A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology 2006;131:1381-91.
• 15. Dohil R, Newbury R, Fox L, et al. Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial. Gastroenterology 2010;139:418-29.
• 16. Schaefer ET, Fitzgerald JF, Molleston JP, et al. Comparison of oral prednisone and topical fluticasone in the treatment of eosinophilic esophagitis: a randomized trial in children. Clin Gastroenterol Hepatol 2008;6:1673.