Kronik Prostatit Kategori Tip IIIA / Kronik Pelvik Ağrı Sendromlu Hastalarda Antioksidan Tedavinin Semptomlar Üzerine Etkisi

Öz

Amaç: Çalışmanın amacı kronik prostatit kategori tip IIIA / kronik pelvik ağrı sendromlu KP/KPAS hastalarda antioksidan tedavinin semptomlar üzerine etkisinin değerlendirilmesidir.Gereç ve Yöntemler: Ekim 2016 ile Aralık 2017 arasında antioksidan ajan olan Progeny-M® ile tedavi edilen KP/KPAS kategori IIIA hastaların verileri retrospektif olarak değerlendirildi. Tedavi öncesi ve tedavi sonrası semptomların değerlendirilmesinde National Institute of Health- Kronik Prostatit Semptom İndeksi NIH-KPSİ kullanıldı. Tedaviden sonra NIH-KPSİ toplam skorunda %25’ten fazla azalma tedaviye yanıt olarak kabul edildi. P

Anahtar Kelimeler

• Kronik prostatit, Kronik pelvik ağrı sendromu, Antioksidan tedavi, Kronik prostatit semptom indeksi

Efficacy of Antioxidant Treatment on the Symptoms of Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome Category IIIA

Abstract

Objective: The aim of this study was to evaluate the effect of antioxidant treatment on the symptoms in patients with chronic prostatitis/chronic pelvic pain syndrome CP/CPPS category IIIA.Material and Methods: We retrospectively evaluated the data of patients with chronic prostatitis/chronic pelvic pain syndrome category IIIA who were treated by Progeny- M®, an antioxidant agent, between October 2016 and December 2017. The pretreatment and posttreatment symptoms were assessed using the National Institutes of Health-Chronic Prostatitis Symptom Index NIH-CPSI . A reduction of the NIH-CPSI total score by ≥25% after the treatment was accepted as an improvement. A value of P < 0.05 was considered statistically significant.Results: Thirty-five out of 53 patients diagnosed with chronic prostatitis were CP/CPPS category IIIA. Seventeen of them were treated with antioxidant agent Progeny- M® for a month. Mean NIH-CPSI total score was significantly decreased after the treatment with Progeny-M® compared to the pretreatment mean score p < 0.001 . Pretreatment mean pain, urinary and quality of life scores of NIH- CPSI 12.1±3.8, 4.7±2.8, 7.6±2.7, respectively were significantly decreased compared to posttreatment scores 8.2±4.2, 3.1±2.0, 5.2±2.6 p < 0.001, p=0.002, p=0.004, respectively .Conclusion: The mean total, pain, urinary and quality of life NIH-CPSI scores significantly decreased after 4 weeks of Progeny-M® treatment in patients with CP/CPPS category IIIA. 58.8% the patients had improved NIH-CSPI scores after the treatment

Keywords

• Chronic prostatitis, Chronic pelvic pain syndrome, Antioxidant therapy, Chronic prostatitis symptom index

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