Paraneoplastic Polycythemia Secondary to Testicular Mixed Paraneoplastic Polycythemia Secondary to Testicular Mixed Germ Cell Tumor Germ Cell Tumor

Abstract

Paraneoplastic syndrome PNS is characterised by a clinical manifestation due to humoral factors such as hormones or cytokines secreted by tumor cells or by an immune response against the tumor. This clinical condition usually disappears by treatment of primary disease or recurs with disease progression. Development of polycythemia as a PNS is rare in the literature and is particularly reported to occur in renal cell carcinoma, hepatocellular carcinoma and gynecological cancers. However, there is only a small number of paraneoplastic polycythemia cases associated with germ cell tumors GCT . Herein, we report an uncommon case of paraneoplastic polycythemia due to testicular cancer

Keywords

• Secondary, Erythrocytosis, Testicular cancer, Paraneoplastic, Mixed germ cell

Mikst Germ Hücreli Testis Tümörüne İkincil Gelişen Paraneoplastik Polisitemi

Öz

Paraneoplastik sendrom PNS tümör tarafından salınan hormonal ya da tümöre yanıt olarak immün sistem tarafından salınan sitokinlerce oluşan klinik bir durumdur. Bu klinik durum çoğunlukla altta yatan primer tümörün tedavisi ile ortadan kalkmakta ya da tümörün ilerlemesi ile tekrar ortaya çıkmaktadır. Literatürde paraneoplastik polisitemi olguları çok nadirdir ve genellikle altta yatan renal hücreli kanser, hepatoselüler kanser ve jinekolojik kanserlere bağlı olgular olarak bildirilmiştir. Literatürde çok az sayıda germ hücreli tümör ve paraneoplastik polisitemi birlikteliği bildirilmiştir. Bu nedenle biz bu nadir birlikteliğe dikkat çekmek için testis kanserli hastada saptanan paranoplastik polisitemi olgusunu sunduk

Anahtar Kelimeler

• İkincil, Eritrositoz, Testis kanseri, Paraneoplastik, Mikst germ hücreli

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