Primer Vajinal Non-Hodgkin Lenfoma: Olgu Sunumu

Öz

Primer non-hodgkin lenfoma kadın genital sistemde çok nadir olarak karşımıza çıkmaktadır. Standart bir tedavi şekli olmamakla birlikte cerrahi, kemoterapi ve radyoterapi tedavi seçenekleri tek başına veya kombine olarak kullanılmaktadır. Primer vajen lenfomalı 65 yaşındaki hastamıza kemoterapi ve radyoterapi tedavi seçenekleri uygulandı. Olgu sunumumuzda, klinik ve tedavi özellikleri ile 5 yıllık takip sonuçları değerlendirildi

Anahtar Kelimeler

• Non-hodgkin lenfoma, Vajen, Radyoterapi

Primary Non-Hodgkin Lymphoma of the Vagina: Case Report

Abstract

Primary malignant lymphoma of the female genital tract is extremely rare. Although a standard of treatment has not been defi ned, treatment regimens have included surgery, radiotherapy, chemotherapy alone or in combination. A 65-year-old patient with primary vaginal lymphoma received chemotherapy and radiotherapy. We evaluated the clinical features and treatment and the 5-year follow-up results in this case

Keywords

• Non-hodgkin lymphoma, Vagina, Radiotherapy

References

1. Freeman C, Berg JW, Cutler SJ. Occurrence and prognosis of extranodal lymphomas. Cancer 1972; 29:252–60.
2. Dang HT, Terk MR, Colletti PM, Schlaerth JB, Curtin JP. Primary lymphoma of the cervix: MRI fi ndings with gadolinium. Magn Reson Imaging 1991; 9:941-4.
3. Ragupathy K, Bappa L. Primary vaginal non-Hodgkin lymphoma: Gynecologic diagnosis of a hematologic malignancy. J Low Genit Tract Dis 2013; 17:326-9.
4. Lonardi F, Ferrari V, Pavanato G, Bonciarelli G, Jirillo A, Balli M. Primary lymphoma of the vagina. A case report. Haematologica 1994; 79:182-3.
5. Kosari F, Daneshbod Y, Parwaresch R, Krams M, Wacker HH. Lymphomas of the female genital tract. A study of 186 cases and review of the literature. Am J Surg Pathol 2005; 29:1512-20.
6. Pham DC, Guthrie TH, Ndubisi B. HIV-associated primary cervical non-Hodgkin’s lymphoma and two other cases of primary pelvic non-Hodgkin’s lymphoma. Gynecologic Oncology 2003; 90: 204–6.
7. Silva V, Correia P, Oliveira N, Sá L. Primary vaginal non- hodgkin’s lymphoma: Report of a rare clinical entity. Clin Pract 2015; 5:821.
8. Muntz HG, Ferry JA, Flynn D, Fuller AF, Tarraza HM. Stage IE primary malignant lymphomas of the uterine cervix. Cancer 1991; 68:2023-32.

9. Harris NL, Scully RE. Malignant lymphoma and granulocytic sarcoma of the uterus and vagina. Cancer 1984; 53:2530-45.
10. Stroh EL, Besa PC, Cox JD, Fuller LM, Cabanillas FF. Treatment of patients with lymphomas of the uterus or cervix with combination chemotherapy and radiation therapy Cancer 1995; 75:2392-9.
11. Signorelli M, Maneo A, Cammarota S, Isimbaldi G, Garcia Parra R, Perego P, Maria Pogliani E, Mangioni C Conservative management in primary genital lymphomas: The role of chemotherapy, Gynecologic Oncology 2007; 104:416–21.