Angiosarcoma Developing After Radiotherapy in The Breast: Case Report

Year 2024, , 568 - 571, 19.09.2024

Miray Maden , Enes Şahin , Ahmet Tuğrul Eruyar , Nihat Zafer Utkan

https://doi.org/10.53394/akd.1371604

Abstract

Angiosarcomas are aggressive, malignant tumors originating from the endothelium.
These tumors, which occur primarily and secondarily in the breast, constitute less
than 1% of breast malignancies. The most common risk factors include radiotherapy
and chronic lymphedema. Survival is quite low in these tumors, which tend
to frequently recur locally and metastasize. Due to its rarity, there is no standard
treatment regimen for this disease. Treatment includes surgery, chemotherapy and
radiotherapy. Diagnosis is made late because it is often confused with other skin
lesions. Angiosarcoma should be considered in the differential diagnosis of newly
developing suspicious lesions in patients with a history of radiotherapy to the breast.

Keywords

Breast cancer, radiotrerapy, angiosarcoma

Memede Radyoterapi Sonrası Gelişen Anjiosarkom: Olgu Sunumu

Abstract

Anjiosarkomlar endotel hücrelerden köken alan agresif, malign tümörlerdir. Memede
primer ve sekonder olarak ortaya çıkan bu tümörler meme malignitelerinin
%1’inden daha azını oluşturur. Risk faktörleri arasında en sık radyoterapi ve kronik
lenf ödem yer almaktadır. Sıklıkla lokal nüks ve metastaz yapma eğilimde olan
bu tümörlerde sağkalım oldukça düşüktür. Nadir görülmesi sebebiyle bu hastalığın
standart bir tedavi rejimi yoktur. Tedavisinde cerrahi, kemoterapi ve radyoterapi yer
almaktadır. Sıklıkla diğer deri lezyonları ile karıştığı için geç tanı konulmaktadır.
Memede radyoterapi öyküsü olan hastalarda yeni gelişen şüpheli lezyonlar için anjiosarkom
ayırıcı tanıda düşünülmelidir.

Keywords

Meme kanseri, radyoterapi, anjiosarkom

Supporting Institution

kocaeli üniversitesi tıp fakültesi

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