Memede Radyoterapi Sonrası Gelişen Anjiosarkom: Olgu Sunumu

Abstract

Anjiosarkomlar endotel hücrelerden köken alan agresif, malign tümörlerdir. Memede primer ve sekonder olarak ortaya çıkan bu tümörler meme malignitelerinin %1’inden daha azını oluşturur. Risk faktörleri arasında en sık radyoterapi ve kronik lenf ödem yer almaktadır. Sıklıkla lokal nüks ve metastaz yapma eğilimde olan bu tümörlerde sağkalım oldukça düşüktür. Nadir görülmesi sebebiyle bu hastalığın standart bir tedavi rejimi yoktur. Tedavisinde cerrahi, kemoterapi ve radyoterapi yer almaktadır. Sıklıkla diğer deri lezyonları ile karıştığı için geç tanı konulmaktadır. Memede radyoterapi öyküsü olan hastalarda yeni gelişen şüpheli lezyonlar için anjiosarkom ayırıcı tanıda düşünülmelidir.

Keywords

• Meme kanseri
• radyoterapi
• anjiosarkom

Angiosarcoma Developing After Radiotherapy in The Breast: Case Report

Abstract

Angiosarcomas are aggressive, malignant tumors originating from the endothelium. These tumors, which occur primarily and secondarily in the breast, constitute less than 1% of breast malignancies. The most common risk factors include radiotherapy and chronic lymphedema. Survival is quite low in these tumors, which tend to frequently recur locally and metastasize. Due to its rarity, there is no standard treatment regimen for this disease. Treatment includes surgery, chemotherapy and radiotherapy. Diagnosis is made late because it is often confused with other skin lesions. Angiosarcoma should be considered in the differential diagnosis of newly developing suspicious lesions in patients with a history of radiotherapy to the breast.

Keywords

• Breast cancer
• radiotrerapy
• angiosarcoma

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