Research Article

Evaluation of the Relationship Between Musculoskeletal Problems and Cognitive Disorders in Alzheimer's Patients

Volume: 11 Number: 2 May 28, 2025
EN TR

Evaluation of the Relationship Between Musculoskeletal Problems and Cognitive Disorders in Alzheimer's Patients

Abstract

Objective: The objective of this study was to evaluate musculoskeletal problems and cognitive disorders that may be seen in individuals with Alzheimer's disease (AD) and to determine the interaction between these problems. Material and Methods: Twenty-five individuals diagnosed with AD by a neurologist were included in the study. The participants' demographic data was recorded, a posture analysis was performed, and Mini-Mental State Examination (MMSE), Barthel Index (BI), and Global Deterioration Scale (GDS) were applied. Results: Posture analyses revealed anterior head tilt in 80%, shoulder protraction in 76%, collapsed chest type in 8%, increased thoracic kyphosis in 84%, genu varum in 12%, and hallux valgus in 32%. There was a significant correlation between the MMSE results of the individuals and the results of BI and GDS (p=0.024 and p=0.002). In addition, it was determined that the dependency levels in BI increased significantly as the stages of the GDS increased (p=0.008). At the same time, there was no significant relationship between the education status and the stages of the GDS. Conclusion: Musculoskeletal disorders are likely to develop in individuals with AD experiencing dementia and complete functional dependence. Therefore, promoting physiotherapy practices along with medical treatment is important to improve functional dependence and cognitive impairment.

Keywords

Ethical Statement

The study was approved by the Clinical Research Ethics Committee with the decision dated 23.12.2014 and numbered 2015/11. The rights of all participants were protected and written and verbal informed consent was obtained in accordance with the principles of the Declaration of Helsinki.

References

  1. 1. Mehta RI, Schneider JA. What is ‘Alzheimer's disease’? The neuropathological heterogeneity of clinically defined Alzheimer's dementia. Current opinion in neurology 2021; 34(2):237-45.
  2. 2. Patterson C. World alzheimer report 2018. 2018.
  3. 3. Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG, Dias A, Fox N, Gitlin LN, Howard R, Kales HC, Kivimäki M, Larson EB, Ogunniyi A, Orgeta V, Ritchie K, Rockwood K, Sampson EL, Samus S, Schneider LS, Selbæk G, Teri L, Mukadamet N. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. The Lancet 2020; 396(10248):413-46.
  4. 4. Oh ES, Rabins PV. Dementia (Japanese Version). Annals of internal medicine 2019; 171(5):JITC33-JITC48.
  5. 5. Sheppard O, Coleman M. Alzheimer’s disease: etiology, neuropathology and pathogenesis. Exon Publications 2020:1-21.
  6. 6. De la Rosa A, Olaso-Gonzalez G, Arc-Chagnaud C, Millan F, Salvador-Pascual A, García-Lucerga C, Blasco-Lafarga C, Garcia-Dominguez E, Carretero A, Correas AG, Vina J, Gomez-Cabreraet MC. Physical exercise in the prevention and treatment of Alzheimer's disease. Journal of sport and health science 2020; 9(5):394-404.
  7. 7. Zhang X-X, Tian Y, Wang Z-T, Ma Y-H, Tan L, Yu J-T. The epidemiology of Alzheimer’s disease modifiable risk factors and prevention. The journal of prevention of Alzheimer's disease 2021; 8:313-21.
  8. 8. Tarawneh R, Holtzman DM. The clinical problem of symptomatic Alzheimer disease and mild cognitive impairment. Cold Spring Harbor perspectives in medicine 2012; 2(5):a006148.

Details

Primary Language

English

Subjects

Neurology and Neuromuscular Diseases , Physiotherapy , Aged Health Care

Journal Section

Research Article

Early Pub Date

May 22, 2025

Publication Date

May 28, 2025

Submission Date

March 20, 2024

Acceptance Date

May 13, 2024

Published in Issue

Year 2025 Volume: 11 Number: 2

Vancouver
1.Özden Gökçek, Mine Argalı Denız, Esra Doğru Hüzmeli, Miray Başer, Ferve Türkeli, Nihan Katayıfçı, Fatma Öz, Kader Kuş, Tuba Yılmaz, Oğuzhan Yılmaz, İsmet Murat Melek. Evaluation of the Relationship Between Musculoskeletal Problems and Cognitive Disorders in Alzheimer’s Patients. Akd Med J. 2025 May 1;11(2):208-15. doi:10.53394/akd.1455569