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Acil Peripartum Histerektomi: Bir Üniversite Hastanesinin 20 Yıllık Deneyimi

Year 2017, Volume: 3 Issue: 3, 165 - 169, 01.01.2017

Abstract

Amaç: Peripartum histerektomi sıklığı tüm dünyada giderek artmakta olan, obstetrik kanamaların tedavisinde son basamak olarak uygulanan hayat kurtarıcı bir cerrahi müdahaledir. Özellikle artan sezaryen hızları ile birlikte gelişen plasental anomaliler plasenta previa ve invazyon anomalileri peripartum histerektominin önemini artırmaktadır.Çalışmanın amacı, peripartum histerektominin bir üniversite kliniğindeki risk faktörlerini, insidansını endikasyonlarını, yönetim stratejilerini ve komplikasyonlarını incelemektir.Gereç ve Yöntemler: Bu retrospektif çalışmaya Mart 1997 ile Mart 2017 tarihleri arasında kliniğimizde doğum sonrası ilk 24 saat içinde peripartum histerektomi yapılan olguları dahil edilmiştir. Olguların demografik verileri, plasental anomali varlığı, histerektomi endikasyonları, yapıldı ise histerektomiye ek cerrahi müdahaleler, intraoperatif komplikasyonlar, transfüzyon ihtiyacı, verilen kan ürünü tipleri ve miktarları ile maternal ve perinatal mortaliteleri incelenmiştir.Bulgular: Kliniğimizde 20 yıl içinde 23 peripartum histerektomi yapılmış olup bu müdahale ‰ 1,7 sıklıkla uygulanmıştır. Peripartum histerektomi endikasyonları arasında en sık olarak plasenta invazyon anomalileri n=8; %34,8 , ikinci en sık olarak ise uterin atoni n=7; %30,4 olarak yer almaktaydı. Plasental anomalilerin plasenta previa ve invazyon anomalileri toplam oranı %52,17 olarak tespit edilmişti. Hastaların tamamına eritrosit süspansiyonu verilmiş olup verilen ortalama eritrosit süspansiyonu miktarı 11,52 ± 9,27 ünitedir. Perinatal mortalite hızı ‰ 120 iken maternal mortalite hızı ‰ 4,3 n=1 olarak tespit edilmiştir.Sonuç: Çalışma plasental anomalilere plasenta previa ve invazyon anomalileri bağlı peripartum histerektomi sıklığının giderek artığını göstermektedir. Bu nedenle bu problemlerin antenatal dönemde tanısının konması ve bu hastaların doğum yönetiminin tecrübeli bir ekip tarafından multidisipliner yaklaşımla yapılması gerekmektedir

References

  • Drife J. Management of primary postpartum haemorrha- ge. Br J Obstet Gynaecol 1997;104: 275-7.
  • Whiteman MK. Kuklina E, Hillis SD, Jamieson DJ, Meikle SF, Posner SF, Marchbanks PA. Incidence and determinants of peripartum hysterectomy. Obstet Gynecol 2006;108(6):1486-92.
  • Flood KM, Said S, Geary M, Robson M, Fitzpatrick C, Malone FD. Changing trends in peripartum hysterectomy over the last 4 decades. Am J Obstet Gynecol 2009; 200(6):1-6.
  • de la Cruz CZ, Thompson EL, O’Rourke K, Nembhard WN. Cesarean section and the risk of emergency peripartum hysterectomy in high-income countries: A systematic review. Arch Gynecol Obstet 2015;292(6): 1201-15.
  • Bateman BT, Mhyre JM, Callaghan WM, Kuklina EV. Peripartum hysterectomy in the United States: Nationwide 14 year experience. Am J Obstet Gynecol 2012; 206(1): 1-8.
  • Silver RM, Landon MB, Rouse DJ, Leveno KJ, Spong CY, Thom EA, Moawad AH, Caritis SN, Harper M, Wapner RJ, Sorokin Y, Miodovnik M, Carpenter M, Peaceman AM, O'Sullivan MJ, Sibai B, Langer O, Thorp JM, Ramin SM, Mercer BM; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol 2006; 107(6):1226-32.
  • Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, ICON- INSTITUT Public Sector GmbH BNB Danışmanlık. Ulusal Anne Ölümleri Çalışması, 2005.
  • Todman D. A history of caesarean section: From ancient world to the modern era. Aust N Z J Obstet Gynaecol 2007;47(5):357-61.
  • Tapisiz OL, Altinbas SK, Yirci B, Cenksoy P, Kaya AE, Dede S, Kandemir O. Emergency peripartum hysterectomy in a tertiary hospital in Ankara, Turkey: A 5-year review. Arch Gynecol Obstet 2012;286(5):1131-4.
  • Demirci O, Tuğrul AS, Yilmaz E, Tosun Ö, Demirci E, Eren YS. Emergency peripartum hysterectomy in a tertiary obstetric center: Nine years evaluation. J Obstet Gynaecol Res 2011; 37(8):1054-60.
  • Yalinkaya A, Güzel AI, Kangal K. Emergency peripartum hysterectomy: 16-year experience of a medical hospital. J Chin Med Assoc 2010; 73(7):360-3.
  • Karayalcin R, Ozcan S, Ozyer S, Mollamahmutoglu L, Danisman N. Emergency peripartum hysterectomy. Arch Gynecol Obstet 2011; 283(4):723-7.
  • Güngördük K, Yildirim G, Dugan N, Polat I, Sudolmus S, Ark C. Peripartum hysterectomy in Turkey: A case- control study. J Obstet Gynaecol 2009; 29(8):722-8.
  • Kayabasoglu F, Guzin K, Aydogdu S, Sezginsoy S, Turkgeldi L, Gunduz G. Emergency peripartum hysterectomy in a tertiary Istanbul hospital. Arch Gynecol Obstet 2008; 278(3):251-6.
  • Zeteroglu S, Ustun Y, Engin-Ustun Y, Sahin G, Kamaci M. Peripartum hysterectomy in a teaching hospital in the Eastern Region of Turkey. Eur J Obstet Gynecol Reprod Biol 2005; 120(1):57-62.
  • Kwee A, Bots ML, Visser GH, Bruinse HW. Emergency peripartum hysterectomy: A prospective study in The Netherlands. Eur J Obstet Gynecol Reprod Biol 2006; 124(2):187-92.
  • Engelsen IB, Albrechtsen S, Iversen OE. Peripartum hysterectomy-incidence and maternal morbidity. Acta Obstet Gynecol Scand 2001; 80(5):409-12.
  • Chen M, Zhang L, Wei Q , Fu X, Gao Q , Liu X. Peripartum hysterectomy between 2009 and 2010 in Sichuan, China. Int J Gynaecol Obstet 2013; 120(2):183- 6.
  • Jou HJ, Hung HW, Ling PY, Chen SM, Wu SC. Peripartum hysterectomy in Taiwan. Int J Gynaecol Obstet 2008; 101(3):269-72.
  • Yoong W, Massiah N, Oluwu A. Obstetric hysterectomy: Changing trends over 20 years in a multiethnic high risk population. Arch Gynecol Obstet 2006; 274(1):37-40.
  • Sakse A, Weber T, Nickelsen C, Secher NJ. Peripartum hysterectomy in Denmark 1995-2004. Acta Obstet Gynecol Scand 2007; 86(12):1472-5.
  • Joseph KS, Rouleau J, Kramer MS, Young DC, Liston RM, Baskett TF, Maternal Health Study Group of the Canadian Perinatal Surveillance System. Investigation of an increase in postpartum haemorrhage in Canada. BJOG 2007; 114(6):751-9.
  • Orbach A, Levy A, Wiznitzer A, Mazor M, Holcberg G, Sheiner E. Peripartum cesarean hysterectomy: Critical analysis of risk factors and trends over the years. J Matern Fetal Neonatal Med 2011; 24(3):480-4.
  • Rossi AC, Lee RH, Chmait RH. Emergency postpartum hysterectomy for uncontrolled postpartum bleeding: A systematic review. Obstet Gynecol 2010; 115(3):637-44.
  • Jauniaux E, Bhide A, Prenatal Ultrasound Diagnosis and Outcome of Placenta Previa Accreta after Caesarean Delivery: A Systematic Review and Meta-Analysis. Am J Obstet Gynecol 2017; 217(1):27-36.
  • Silver RM, Fox KA, Barton JR, Abuhamad AZ, Simhan H, Huls CK, Belfort MA, Wright JD. Center of excellence for placenta accreta. Am J Obstet Gynecol 2015; 212(5):561-8.
  • Shamshirsaz AA, Fox KA, Salmanian B, Diaz-Arrastia CR, Lee W, Baker BW, Ballas J, Chen Q , Van Veen TR, Javadian P, Sangi-Haghpeykar H, Zacharias N, Welty S, Cassady CI, Moaddab A, Popek EJ, Hui SK, Teruya J, Bandi V, Coburn M, Cunningham T, Martin SR, Belfort MA. Maternal morbidity in patients with morbidly adherent placenta treated with and without a standardized multidisciplinary approach. Am J Obstet Gynecol 2015; 212(2):1-9.
  • Thurn L, Lindqvist PG, Jakobsson M, Colmorn LB, Klungsoyr K, Bjarnadóttir RI, Tapper AM, Bİrdahl PE, Gottvall K, Petersen KB, Krebs L, Gissler M1, Langhoff- Roos J, Källen K. Abnormally invasive placenta- prevalence, risk factors and antenatal suspicion: Results from a large population-based pregnancy cohort study in the Nordic countries. BJOG 2016; 123(8):1348-55.
  • Finberg HJ, Williams JW. Placenta accreta: Prospective sonographic diagnosis in patients with placenta previa and prior cesarean section. J Ultrasound Med 1992; 11(7): 333-43.
  • Comstock CH, Love JJ Jr, Bronsteen RA, Lee W, Vettraino IM, Huang RR, Lorenz RP. Sonographic detection of placenta accreta in the second and third trimesters of pregnancy. Am J Obstet Gynecol, 2004; 190(4):1135-40.
  • Jauniaux E, Collins SL, Jurkovic D, Burton GJ. Accreta placentation: A systematic review of prenatal ultrasound imaging and grading of villous invasiveness. Am J Obstet Gynecol 2016; 215(6):712-721.

Emergency Peripartum Hysterectomy: 20-Year Experience of a University Hospital

Year 2017, Volume: 3 Issue: 3, 165 - 169, 01.01.2017

Abstract

Objective: Peripartum hysterectomy is a lifesaving procedure that is performed as the last step in the management of massive obstetric hemorrhage. Its incidence is increasing worldwide. Placental abnormalities that are associated with high cesarean rates are of utmost importance in the concept of peripartum hysterectomy.The purpose of this study was to elucidate the risk factors, incidence indications, management strategies and complications of peripartum hysterectomy in a university setting.Material and Methods: This retrospective study included the patients who gave birth and underwent hysterectomy in the 24h after delivery at our clinic between March 1997 and March 2017. Demographic characteristics, the presence of placental abnormalities, indications of hysterectomy, surgical interventions other than hysterectomy, intraoperative complications, need of transfusion, types and amount of transfused blood products, and perinatal and maternal mortality were examined.Results: There were 23 hysterectomy cases in 20 years with an incidence of 1.7‰. The most common indications were placental Results: There were 23 hysterectomy cases in 20 years with an incidence of 1.7‰. The most common indications were placental invasion anomalies n=8; 34.8% and uterine atony n=7; 30.4% . Total rate of placental abnormalities was 52.17%. All patients were given erythrocyte suspension with a mean amount of 11.52 ± 9.27 units per patient. Perinatal mortality rate was 120‰ and maternal mortality rate was 4.3‰ n = 1 . Conclusion: This study shows that the frequency of peripartum hysterectomy due to placental anomalies is increasing steadily. The diagnosis of these problems should therefore be made in the antenatal period and the management of these patients should be conducted with the multidisciplinary approach of an experienced team

References

  • Drife J. Management of primary postpartum haemorrha- ge. Br J Obstet Gynaecol 1997;104: 275-7.
  • Whiteman MK. Kuklina E, Hillis SD, Jamieson DJ, Meikle SF, Posner SF, Marchbanks PA. Incidence and determinants of peripartum hysterectomy. Obstet Gynecol 2006;108(6):1486-92.
  • Flood KM, Said S, Geary M, Robson M, Fitzpatrick C, Malone FD. Changing trends in peripartum hysterectomy over the last 4 decades. Am J Obstet Gynecol 2009; 200(6):1-6.
  • de la Cruz CZ, Thompson EL, O’Rourke K, Nembhard WN. Cesarean section and the risk of emergency peripartum hysterectomy in high-income countries: A systematic review. Arch Gynecol Obstet 2015;292(6): 1201-15.
  • Bateman BT, Mhyre JM, Callaghan WM, Kuklina EV. Peripartum hysterectomy in the United States: Nationwide 14 year experience. Am J Obstet Gynecol 2012; 206(1): 1-8.
  • Silver RM, Landon MB, Rouse DJ, Leveno KJ, Spong CY, Thom EA, Moawad AH, Caritis SN, Harper M, Wapner RJ, Sorokin Y, Miodovnik M, Carpenter M, Peaceman AM, O'Sullivan MJ, Sibai B, Langer O, Thorp JM, Ramin SM, Mercer BM; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol 2006; 107(6):1226-32.
  • Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, ICON- INSTITUT Public Sector GmbH BNB Danışmanlık. Ulusal Anne Ölümleri Çalışması, 2005.
  • Todman D. A history of caesarean section: From ancient world to the modern era. Aust N Z J Obstet Gynaecol 2007;47(5):357-61.
  • Tapisiz OL, Altinbas SK, Yirci B, Cenksoy P, Kaya AE, Dede S, Kandemir O. Emergency peripartum hysterectomy in a tertiary hospital in Ankara, Turkey: A 5-year review. Arch Gynecol Obstet 2012;286(5):1131-4.
  • Demirci O, Tuğrul AS, Yilmaz E, Tosun Ö, Demirci E, Eren YS. Emergency peripartum hysterectomy in a tertiary obstetric center: Nine years evaluation. J Obstet Gynaecol Res 2011; 37(8):1054-60.
  • Yalinkaya A, Güzel AI, Kangal K. Emergency peripartum hysterectomy: 16-year experience of a medical hospital. J Chin Med Assoc 2010; 73(7):360-3.
  • Karayalcin R, Ozcan S, Ozyer S, Mollamahmutoglu L, Danisman N. Emergency peripartum hysterectomy. Arch Gynecol Obstet 2011; 283(4):723-7.
  • Güngördük K, Yildirim G, Dugan N, Polat I, Sudolmus S, Ark C. Peripartum hysterectomy in Turkey: A case- control study. J Obstet Gynaecol 2009; 29(8):722-8.
  • Kayabasoglu F, Guzin K, Aydogdu S, Sezginsoy S, Turkgeldi L, Gunduz G. Emergency peripartum hysterectomy in a tertiary Istanbul hospital. Arch Gynecol Obstet 2008; 278(3):251-6.
  • Zeteroglu S, Ustun Y, Engin-Ustun Y, Sahin G, Kamaci M. Peripartum hysterectomy in a teaching hospital in the Eastern Region of Turkey. Eur J Obstet Gynecol Reprod Biol 2005; 120(1):57-62.
  • Kwee A, Bots ML, Visser GH, Bruinse HW. Emergency peripartum hysterectomy: A prospective study in The Netherlands. Eur J Obstet Gynecol Reprod Biol 2006; 124(2):187-92.
  • Engelsen IB, Albrechtsen S, Iversen OE. Peripartum hysterectomy-incidence and maternal morbidity. Acta Obstet Gynecol Scand 2001; 80(5):409-12.
  • Chen M, Zhang L, Wei Q , Fu X, Gao Q , Liu X. Peripartum hysterectomy between 2009 and 2010 in Sichuan, China. Int J Gynaecol Obstet 2013; 120(2):183- 6.
  • Jou HJ, Hung HW, Ling PY, Chen SM, Wu SC. Peripartum hysterectomy in Taiwan. Int J Gynaecol Obstet 2008; 101(3):269-72.
  • Yoong W, Massiah N, Oluwu A. Obstetric hysterectomy: Changing trends over 20 years in a multiethnic high risk population. Arch Gynecol Obstet 2006; 274(1):37-40.
  • Sakse A, Weber T, Nickelsen C, Secher NJ. Peripartum hysterectomy in Denmark 1995-2004. Acta Obstet Gynecol Scand 2007; 86(12):1472-5.
  • Joseph KS, Rouleau J, Kramer MS, Young DC, Liston RM, Baskett TF, Maternal Health Study Group of the Canadian Perinatal Surveillance System. Investigation of an increase in postpartum haemorrhage in Canada. BJOG 2007; 114(6):751-9.
  • Orbach A, Levy A, Wiznitzer A, Mazor M, Holcberg G, Sheiner E. Peripartum cesarean hysterectomy: Critical analysis of risk factors and trends over the years. J Matern Fetal Neonatal Med 2011; 24(3):480-4.
  • Rossi AC, Lee RH, Chmait RH. Emergency postpartum hysterectomy for uncontrolled postpartum bleeding: A systematic review. Obstet Gynecol 2010; 115(3):637-44.
  • Jauniaux E, Bhide A, Prenatal Ultrasound Diagnosis and Outcome of Placenta Previa Accreta after Caesarean Delivery: A Systematic Review and Meta-Analysis. Am J Obstet Gynecol 2017; 217(1):27-36.
  • Silver RM, Fox KA, Barton JR, Abuhamad AZ, Simhan H, Huls CK, Belfort MA, Wright JD. Center of excellence for placenta accreta. Am J Obstet Gynecol 2015; 212(5):561-8.
  • Shamshirsaz AA, Fox KA, Salmanian B, Diaz-Arrastia CR, Lee W, Baker BW, Ballas J, Chen Q , Van Veen TR, Javadian P, Sangi-Haghpeykar H, Zacharias N, Welty S, Cassady CI, Moaddab A, Popek EJ, Hui SK, Teruya J, Bandi V, Coburn M, Cunningham T, Martin SR, Belfort MA. Maternal morbidity in patients with morbidly adherent placenta treated with and without a standardized multidisciplinary approach. Am J Obstet Gynecol 2015; 212(2):1-9.
  • Thurn L, Lindqvist PG, Jakobsson M, Colmorn LB, Klungsoyr K, Bjarnadóttir RI, Tapper AM, Bİrdahl PE, Gottvall K, Petersen KB, Krebs L, Gissler M1, Langhoff- Roos J, Källen K. Abnormally invasive placenta- prevalence, risk factors and antenatal suspicion: Results from a large population-based pregnancy cohort study in the Nordic countries. BJOG 2016; 123(8):1348-55.
  • Finberg HJ, Williams JW. Placenta accreta: Prospective sonographic diagnosis in patients with placenta previa and prior cesarean section. J Ultrasound Med 1992; 11(7): 333-43.
  • Comstock CH, Love JJ Jr, Bronsteen RA, Lee W, Vettraino IM, Huang RR, Lorenz RP. Sonographic detection of placenta accreta in the second and third trimesters of pregnancy. Am J Obstet Gynecol, 2004; 190(4):1135-40.
  • Jauniaux E, Collins SL, Jurkovic D, Burton GJ. Accreta placentation: A systematic review of prenatal ultrasound imaging and grading of villous invasiveness. Am J Obstet Gynecol 2016; 215(6):712-721.
There are 31 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Melih Velipaşaoğlu This is me

Metin Şentürk This is me

H.mete Tanır This is me

Publication Date January 1, 2017
Published in Issue Year 2017 Volume: 3 Issue: 3

Cite

Vancouver Velipaşaoğlu M, Şentürk M, Tanır H. Acil Peripartum Histerektomi: Bir Üniversite Hastanesinin 20 Yıllık Deneyimi. Akd Med J. 2017;3(3):165-9.