Akut Santral Seröz Koryoretinopatide Dış Retinal Tabakaların Morfolojik Değişiminin Spektral Domain Optik Koherens Tomografi ile Değerlendirilmesi

Year 2019, Volume: 5 Issue: 2, 246 - 250, 01.01.2019

Ali Demircan Abdullah Özkaya Ceren Yeşilkaya Zeynep Alkın Dilek Yaşa Alper Ağca İrfan Perente

Abstract

Amaç: Akut santral seröz koryoretinopatide SSRP , eksternal limitan membran ELM , fotoreseptör iç ve dış segment bileşkesi ve ayrılan retinadaki granüler fırçamsı kenar görünümünü değerlendirmek.Gereç ve Yöntemler: Optik koherens tomografi OKT ile yapılan ölçümlerde fovea merkezi santral alınarak 1000 µm uzunluğundaki bölgede; ELM altında kalan retina alanı ile fotoreseptör iç ve dış segment bandı altındaki en fazla kalınlık ölçümü ilk başvuruda, üçüncü ve altıncı ayda değerlendirildi. Bulgular: Fotoreseptör iç ve dış segment bandı altındaki kalınlık ile ELM altında kalan alan ölçümlerinde başlangıç ve üçüncü ay arasında istatistiksel olarak anlamlı fark görülmezken, üçüncü ay ile altıncı ay arasında anlamlı artış olduğu görüldü. Sonuç: Akut SSRP hastalarında ayrılan retinadaki fırçamsı kenar görünümü, fotoreseptör iç ve dış segment bandı altındaki kalınlık ve ELM altındaki alan eğer retina tekrar yapışmazsa üçüncü aydan sonra artış göstermektedir

Keywords

Fırçamsı kenar, Santral seröz koryoretinopati, Granüler görünüm, Fotoreseptör

Morphological Changes of Outer Retinal Layers in Acute Central Serous Chorioretinopathy Evaluated by Spectral Domain Optical Coherence Tomography

Abstract

Objective: To evaluate changes in thickness beyond the external limiting membrane ELM and the photoreceptor inner and outer segment junction IS/OS in patients with acute central serous chorioretinopathy CSC and a granular brush border appearance of a detached posterior retina.Material and Methods: The retinal area below the ELM at a 1,000 µm diameter zone centered on the fovea, and the greatest thickness below the IS/OS band in this area was measured by optical coherence tomography OCT at baseline, as well as at the 3- and 6-month visits.Results: Sub-IS/OS thickness and the sub-ELM area did not differ statistically between baseline and month 3; however, they significantly increased from month 3 to month 6.Conclusion: In patients with CSC and a brush appearance of the posterior border of the detached retina, sub-IS/OS thickness and sub-ELM area increased after 3 months if the retina was not reattached

Keywords

Brush border, Central serous chorioretinopathy, Granular appearance, IS/OS, ELM

References

• von Grafe A. Ueber central recidivierende retinitis. Graefes Arch Clin Exp Ophthalmol 1866;12:211-15.
• Gass JD. Pathogenesis of disciform detachment of the neuroepiteium. Am J Ophthalmol 1967;63(3):1-139.
• Nicholson B, Noble J, Forooghian F, Meyerle C. Central serous chorioretinopathy: Update on pathophysiology and treatment. Surv Ophthalmol 2013;58:103-26.
• Montero JA, Ruiz-Moreno JM. Optical coherence tomography characterization of idiopathic central serous chorioretinopathy. Br J Ophthalomol 2005;89:562-64.
• Drexler W, Sattamann H, Hermann B, et al. Enhanced visualization of macular pathology with the use of ultrahighresolution optical coherence tomography. Arch Ophthalmol 2003;121:695-706.
• İida T, Kishi S, Hagimura N, Shimizu K. Persistent and bilateral choroidal vascular abnormalities in central serous chorioretinopathy. Retina 1999;19:508-12.
• Matsumoto H, Kishi S, Otani T, Sato T. Elongation of photoreceptor outer segment in central serous chorioretinopathy. Am J Ophthalmol 2008;145:162-8.
• Yu H, Xia GY, Gao MH, et al. Morphologic changes in acute central serous chorioretinopathy evaluated by spectral domain optical coherence tomography. Zhonghua Yan Ke Za Zhi 2011;47:508-15.
• Fujimoto H, Gomi F, Wakabayashi T, et al. Morphologic changes in acute central serous chorioretinopathy evaluated by fourier-domain optical coherence tomography. Opthalmology 2008;115:1494-500.
• Piccolino FC, de la Longrais RR, Ravera G, et al. The foveal photoreceptor layer and visual acuity loss in central serous chorioretinopathy. Am J Ophthalmol 2005; 139: 87-99.
• Ojima Y, Hangai M, Sasahara M, et al. Three- dimensional imaging of the foveal photoreceptor layer in central serous chorioretinopathy using high-speed optical coherence tomography. Ophthalmology 2007;114:2197- 207.
• Ozdemir H, Arf S, Karacorlu M. (Optical coherence tomography in macula diseases) 1st ed. Ankara Güneş Medical Book Printing House, 2015.
• Fisher SK, Lewis GP. Muller cell and neuronal remodeling in retinal detachment and reattachment and their potential consequences for visual recovery: A review and reconsideration of recent data. Vision Res 2003;43: 887-97.
• Malia M. Edwards, D. Scott McLeod, Imran A. Bhutto, Johanna Seddon, Gerard A. Lutty. Müller cell protrusions through the external limiting membrane in aged human retinas. Invest Ophthalmol Vis Sci 2015;56(7):5840.