BibTex RIS Cite

Robot Destekli Laparoskopik Radikal Prostatektomi Hastalarında Üç Farklı Genel Anestezi Yönteminin Postoperatif Böbrek ve Hepatik Fonksiyonlar Üzerine Etkileri

Year 2020, Volume: 6 Issue: 2, 226 - 230, 01.01.2020

Abstract

Amaç: Robotik yardımlı laparoskopik radikal prostatektomi RLRP hastalarına sevofluran, desfluran ve total intravenöz anestezi yöntemlerini uyguladık ve böbrek ve karaciğer fonksiyonları üzerindeki etkilerini karşılaştırdık. Robotik yardımlı laparoskopik radikal prostatektomi hastalarında 3 farklı anestezi yönteminin böbrek ve karaciğer fonksiyonları üzerine etkileri araştırılmamıştır.Gereç ve Yöntemler: Toplam 193 hastaya Sevoflurane, Desflurane veya TIVA grupları için Total İntravenöz Anestezi TIVA uygulandı. Hasta verileri elektronik hasta veri sistemi SARUS taranarak üretildi. Üç grubun preoperatif ve postoperatif laboratuvar bulguları değerlendirildi ve anestezi tiplerinin etkisini izole etmek için çok değişkenli analiz yapıldı.Bulgular: Yaş ortalaması 63.96±6.17 olan RLRP yapılan 193 hasta retrospektif olarak değerlendirildi. Serofluran grubu 48, Desfluran grubu 131 ve TIVA grubu 14 hastadan veriler toplandı. TIVA grubunda, Sevofluran ve Desfluran gruplarına kıyasla, postoperatif böbrek ve karaciğer fonksiyonlarının korunması ve daha az intraoperatif solunum asidozu ile ilişkili avantajlar vardı.Sonuç: Bu bulgular doğrultusunda TIVA iyi tolere edilir ve RLRP ameliyatı için güvenli bir anestezi tekniğidir. RLRP cerrahisinde sevofluran, desfluran ve TIVAʼyı tek tek karşılaştıran başka bir çalışma yoktur ve özellikle postoperatif böbrek ve karaciğer değerlerini ortaya çıkarmak için gelecekteki çalışmalara ihtiyaç vardır

References

  • Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der Kwast T, Mason M, Matveev V, Wiegel T, Zattoni F, Mottet N; European Association of Urology. EAU guidelines on prostate cancer. Part 1: screening, diagnosis. And local treatment with curative intent-update 2013. Eur Urol 2014; 65:124-37.
  • Shen H, Zhang L, Zhou J. Epidermal growth factor- containing fibulin-like extracellular matrix protein 1 (EFEMP1) acts as a potential diagnostic biomarker for prostate cancer. Med Sci Monit 2018; 24:216-22.
  • Deng QK, Lei YG, Lin YL. Prognostic value of Protocadherin 10 (PCDH 10) methylation in serum of prostate cancer patients. Med Sci Monit 2016; 22:516-21.
  • Papachristos A, Basto M, Te Marvelde L, Moon D. Laparoscopic versus robotic-assisted radical prostatectomy: An Australian single-surgeon series. ANZ J Surg 2015; 85:154-8.
  • Tozawa K, Yasui T, Umemoto Y, Mizuno K, Okada A, Kawai N, Takahashi S, Kohri K. Pitfalls of robot-assisted radical prostatectomy: A comparison of positive surgical margins between robotic and laparoscopic surgery. Int J Urol 2014; 21:976-9.
  • Lai HC, Chan SM, Lu CH, Wong CS, Cherng CH, Wu ZF. Planning for operation room efficiency and faster anesthesia wake-up time in open major upper abdominal surgery. Medicine (Baltimore) 2017; 96:e6148.
  • Horng HC, Kuo CP, Ho CC, Wong CS, Yu MH, Cherng CH, Wu CT. Cost analysis of three anesthetic regimens under auditory evoked potentials monitoring in gynecologic laparoscopic surgery. Acta Anesthesiol Taiwan 2007; 45:205-10.
  • Ozkose Z, Ercan B, Unal Y, Yardim S, Kaymaz M, Dogulu F, Pasaoglu A. Inhalation versus total intravenous anesthesia for lumbar disc herniation: Comparison of hemodynamic effects, recovery characteristics, and cost. J Neurosurg Anesthesiol 2001; 13:296-302.
  • Guillonneau B, Cathelineau X, Barret E, Rozet F, Vallancien G. Laparoscopic radical prostatectomy. Preliminary evaluation after 28 interventions. Presse Med 1998; 27:1570-4.
  • Ficarra V, Novara G, Artibani W, Cestari A, Galfano A, Graefen M, Guazzoni G, Guillonneau B, Menon M, Montorsi F, Patel V, Rassweiler J, Van Poppel H. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: A systematic rewiew and cumulative analysis of comparative studies. Eur Urol 2009; 55:1037- 63.
  • Stav K, Rahimi-Levene N, Linder A, Siegel YI, Zisman A. Retropubic radical prostatectomy: Associated blood loss and transfusion requirements-a two-decade perspective review. Isr Med Assoc J 2005; 7:103-6.
  • Ko JS, Gwak MS, Choi SJ, Kim GS, Kim JA, Yang M, Lee SM, Cho HS, Chung IS, Kim MH. The effects of desflurane and propofol-remifentanil on postoperative hepatic and renal functions after right hepatectomy in liver donors. Liver Transpl 2008; 14:1150-8.
  • Liu TC, Lai HC, Lu CH, Huang YS, Hung NK, Cherng CH, Wu ZF. Analysis of anesthesia-controlled operating room time after propofol-based total intravenous anesthesia compared with desflurane anesthesia in functional endoscopic sinus surgery. Medicine (Baltimore) 2018; 97(5):e9805.
  • Mazze RI. Metabolism of the inhaled anesthetics: Implications of enzyme induction. Br J Anaesth 1984; 56 Suppl 1:27S-41S.
  • Kim JW, Kim JD, Yu SB, Ryu SJ. Comparison of hepatic and renal function between inhalation anesthesia with sevoflurane and remifentanil and total intravenous anesthesia with propofol and remifentanil for thyroidectomy. Korean J Anesthesiol 2013; 64:112-6.
  • Nadalin S, Testa G, Malagó M, Beste M, Frilling A, Schroeder T, Jochum C, Gerken G, Broelsch CE. Volumetric and functional recovery of the liver after right hepatectomy for living donation. Liver Transpl 2004; 10:1024-9.
  • Cammu G, Decruyenaere J, Troisi R, de Hemptinne B, Colardyn F, Mortier E. Criteria for immediate postoperative extubation in adult recipients following living-related liver transplantation with total intravenous anesthesia. J Clin Anesth 2003; 15:515-9.

Effects of Three Different Methods of General Anesthesia on Postoperative Renal and Hepatic Functions in Robot-Assisted Laparoscopic Radical Prostatectomy Patients

Year 2020, Volume: 6 Issue: 2, 226 - 230, 01.01.2020

Abstract

Objective: We administered sevoflurane, desflurane and total intravenous anesthesia methods in robotic assisted laparoscopic radical prostatectomy RLRP patients and compared their effects on renal and liver functions. The effects of 3 different anesthesia methods on renal and liver functions in robotic assisted laparoscopic radical prostatectomy patients have not been studied.Material and Methods: A total of 193 patients underwent Total Intravenous Anesthesia TIVA for Sevoflurane, Desflurane or TIVA groups. Patient data was generated by scanning the electronic patient data system SARUS . Preoperative and postoperative laboratory findings of 3 groups were evaluated, and multivariate analysis was performed to isolate the effect of anesthesia types.Results: One hundred and ninety-three patients who underwent RLRP with a mean age of 63.96±6.17 were evaluated retrospectively. Data were collected from 48 patients in seroflurane group, 131 patients in desflurane group and 14 patients in TIVA group. In the TIVA group, compared to the Sevoflurane and Desflurane groups, there were advantages associated with the preservation of postoperative renal and liver functions and less intraoperative respiratory acidosis.Conclusion: TIVA was found to be well tolerated and a safe anesthesia technique for RLRP surgery. There is no other study comparing sevoflurane, desflurane, and TIVA one by one in RLRP surgery, and future studies are needed especially for revealing postoperative renal and hepatic values

References

  • Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der Kwast T, Mason M, Matveev V, Wiegel T, Zattoni F, Mottet N; European Association of Urology. EAU guidelines on prostate cancer. Part 1: screening, diagnosis. And local treatment with curative intent-update 2013. Eur Urol 2014; 65:124-37.
  • Shen H, Zhang L, Zhou J. Epidermal growth factor- containing fibulin-like extracellular matrix protein 1 (EFEMP1) acts as a potential diagnostic biomarker for prostate cancer. Med Sci Monit 2018; 24:216-22.
  • Deng QK, Lei YG, Lin YL. Prognostic value of Protocadherin 10 (PCDH 10) methylation in serum of prostate cancer patients. Med Sci Monit 2016; 22:516-21.
  • Papachristos A, Basto M, Te Marvelde L, Moon D. Laparoscopic versus robotic-assisted radical prostatectomy: An Australian single-surgeon series. ANZ J Surg 2015; 85:154-8.
  • Tozawa K, Yasui T, Umemoto Y, Mizuno K, Okada A, Kawai N, Takahashi S, Kohri K. Pitfalls of robot-assisted radical prostatectomy: A comparison of positive surgical margins between robotic and laparoscopic surgery. Int J Urol 2014; 21:976-9.
  • Lai HC, Chan SM, Lu CH, Wong CS, Cherng CH, Wu ZF. Planning for operation room efficiency and faster anesthesia wake-up time in open major upper abdominal surgery. Medicine (Baltimore) 2017; 96:e6148.
  • Horng HC, Kuo CP, Ho CC, Wong CS, Yu MH, Cherng CH, Wu CT. Cost analysis of three anesthetic regimens under auditory evoked potentials monitoring in gynecologic laparoscopic surgery. Acta Anesthesiol Taiwan 2007; 45:205-10.
  • Ozkose Z, Ercan B, Unal Y, Yardim S, Kaymaz M, Dogulu F, Pasaoglu A. Inhalation versus total intravenous anesthesia for lumbar disc herniation: Comparison of hemodynamic effects, recovery characteristics, and cost. J Neurosurg Anesthesiol 2001; 13:296-302.
  • Guillonneau B, Cathelineau X, Barret E, Rozet F, Vallancien G. Laparoscopic radical prostatectomy. Preliminary evaluation after 28 interventions. Presse Med 1998; 27:1570-4.
  • Ficarra V, Novara G, Artibani W, Cestari A, Galfano A, Graefen M, Guazzoni G, Guillonneau B, Menon M, Montorsi F, Patel V, Rassweiler J, Van Poppel H. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: A systematic rewiew and cumulative analysis of comparative studies. Eur Urol 2009; 55:1037- 63.
  • Stav K, Rahimi-Levene N, Linder A, Siegel YI, Zisman A. Retropubic radical prostatectomy: Associated blood loss and transfusion requirements-a two-decade perspective review. Isr Med Assoc J 2005; 7:103-6.
  • Ko JS, Gwak MS, Choi SJ, Kim GS, Kim JA, Yang M, Lee SM, Cho HS, Chung IS, Kim MH. The effects of desflurane and propofol-remifentanil on postoperative hepatic and renal functions after right hepatectomy in liver donors. Liver Transpl 2008; 14:1150-8.
  • Liu TC, Lai HC, Lu CH, Huang YS, Hung NK, Cherng CH, Wu ZF. Analysis of anesthesia-controlled operating room time after propofol-based total intravenous anesthesia compared with desflurane anesthesia in functional endoscopic sinus surgery. Medicine (Baltimore) 2018; 97(5):e9805.
  • Mazze RI. Metabolism of the inhaled anesthetics: Implications of enzyme induction. Br J Anaesth 1984; 56 Suppl 1:27S-41S.
  • Kim JW, Kim JD, Yu SB, Ryu SJ. Comparison of hepatic and renal function between inhalation anesthesia with sevoflurane and remifentanil and total intravenous anesthesia with propofol and remifentanil for thyroidectomy. Korean J Anesthesiol 2013; 64:112-6.
  • Nadalin S, Testa G, Malagó M, Beste M, Frilling A, Schroeder T, Jochum C, Gerken G, Broelsch CE. Volumetric and functional recovery of the liver after right hepatectomy for living donation. Liver Transpl 2004; 10:1024-9.
  • Cammu G, Decruyenaere J, Troisi R, de Hemptinne B, Colardyn F, Mortier E. Criteria for immediate postoperative extubation in adult recipients following living-related liver transplantation with total intravenous anesthesia. J Clin Anesth 2003; 15:515-9.
There are 17 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Ozkan Gorgulu This is me

Kerem Inanoglu This is me

Bora Dınc This is me

Publication Date January 1, 2020
Published in Issue Year 2020 Volume: 6 Issue: 2

Cite

Vancouver Gorgulu O, Inanoglu K, Dınc B. Effects of Three Different Methods of General Anesthesia on Postoperative Renal and Hepatic Functions in Robot-Assisted Laparoscopic Radical Prostatectomy Patients. Akd Med J. 2020;6(2):226-30.