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Larenks Kanserlerinde Hyoid Kemik İnvazyonu Prognostik Belirteçler İçerisinde Yer Almalı mı?

Year 2020, Volume: 6 Issue: 2, 286 - 288, 01.01.2020

Abstract

Amaç: Larenjektomi yapılan hastalarda hyoid kemik invazyon oranının ortaya konulması ve sonuçlara göre konservatif cerrahi yaklaşımın geliştirilmesidir.Gereç ve Yöntemler: Akdeniz Üniversitesi Kulak Burun Boğaz ve Baş-Boyun Cerrahisi anabilim dalında 2014-2019 yılları arasında larenjektomi yapılan 53 hastanın tıbbi kayıtlarının retrospektif incelenmesi ile veriler elde edilmiştir.Bulgular: Çalışmaya 50 erkek, 3 kadın olmak üzere 53 hasta dahil edildi. Bu hastaların 52’i yassı hücreli karsinom’a sahipken, 1 hasta malign mezenkimal tümör tanısı almıştı. Hastaların T evreleri incelendiğinde; %41,5’nin T4, %18,8’inin T3 olduğu görülmüştür. Hastaların 44’ü %83,01 total larenjektomi, 9’u ise %16,98 parsiyel larenjektomi ile tedavi edilmiştir. Tüm hastaların hyoid kemiği histopatolojik olarak incelenmiştir. Dahil edilen 53 hastanın hiçbirinde hyoid kemik invazyon bulunmamıştır.Sonuç: Larenks kanserlerinde hyoid kemik invazyonuna oldukça ender rastlanır. Hyoid kemik invazyonunun oluşmasını engelleyen faktörlerin başında larenks ve hyoid kemik arasındaki anatomik bariyerlerin doğal koruyucu olarak görev alması gelmektedir. Çalışmamızda hiçbir hastada hyoid kemik invazyonu izlenmedi. Bu bulgular ışığında, özellikle seçilmiş vakalarda hyoid kemiğin korunabileceğini düşünmekteyiz

References

  • Jones TM, De M, Foran B, Harrington K, Mortimore S. Laryngeal cancer: United Kingdom National Multidisciplinary guidelines. J Laryngol Otol 2016; 130(2):S75-S82.
  • Hanna J, Brauer PR, Morse E, Judson B, Mehra S. Is robotic surgery an option for early T-stage laryngeal cancer? Early nationwide results. Laryngoscope 2019; 24. [Epub ahead of print]
  • Hafız G, Başaran B, Ulusan M, Comoğlu S. A new extended supracricoid laryngectomy technique for tongue base and hyoid bone involvement: Crico-glosso- mandibulopexy technique. Kulak Burun Bogaz Ihtis Derg 2014; 24(3):181-4.
  • Timon CI, Gullane PJ, Brown D, Van Nostrand AW. Hyoid bone involvement by squamous cell carcinoma: Clinical and pathological features. Laryngoscope 1992; 102(5):515-20.
  • Spriano G, Mercante G, Anelli A, Cristalli G, Ferreli F. Lateral cervical approach for open laryngeal surgery: Technical notes. Head Neck 2019; 41(3):813-20.
  • Marchetta FC, Sako K, Murphy JB. The periosteum of the mandible and intraoral carcinoma. Am J Surg 1971; 122(6):711-3.
  • Gómez Serrano M, Iglesias Moreno MC, Gimeno Hernández J, Ortega Medina L, Martín Villares C, Poch Broto J. Cartilage invasion patterns in laryngeal cancer. Eur Arch Otorhinolaryngol 2016; 273(7):1863-9.
  • Pan Y, Hong Y, Liang Z, Zhuang W. Survival analysis of distant metastasis of laryngeal carcinoma: Analysis based on SEER database. Eur Arch Otorhinolaryngol. 2019; 276(1):193-201.
  • Ballenger JJ, Snow JB. Otorhinolaryngology head and neck surgery: 15th ed. Philadelphia: Lippincott Williams and Wilkins, 1996: 618.
  • Kirchner JA. Closure after supraglottic laryngectomy. Laryngoscope 1979; 89(8):1343-4.
  • Ogura JH. Surgical pathology of cancer of the larynx. Laryngoscope 1955; 65:867-926.
  • Suoglu Y, Guven M, Kiyak E, Enoz M. Significance of pre-epiglottic space invasion in supracricoid partial laryngectomy with cricohyoidopexy. J Laryngol Otol 2008; 122(6):623-7.
  • Dursun G, Keser R, Aktürk T, Akìner MN, Demireller A, Sak SD. The significance of pre-epiglottic space invasion in supraglottic laryngeal carcinomas. Eur Arch Otorhinolaryngol 1997; 254(1):110-2.

Should Hyoid Bone Invasion be Included in the Prognostic Markers of Laryngeal Cancer? Larenks Kanserlerinde Hyoid Kemik İnvazyonu Prognostik Belirteçler İçerisinde Yer Almalı mı?

Year 2020, Volume: 6 Issue: 2, 286 - 288, 01.01.2020

Abstract

Objective: To determine the rate of hyoid bone invasion in patients undergoing laryngectomy and to develop a conservative surgical approach based on the results.Material and Methods: The data used in the study were gathered by the retrospective analysis of the medical records of 53 patients who underwent laryngectomy during the 2014–2019 period at the Otorhinolaryngology and Head and Neck Surgery Department of Akdeniz University.Results: Fifty-three patients 50 male, 3 female were included in the study. Of these, 52 had squamous cell carcinoma and 1 was diagnosed with a malignant mesenchymal tumor. The examination of the T stages of the patients revealed T4 in 41.5% the patients and T3 in 18.8%. Forty-four patients 83.01% were treated with total laryngectomy and 9 patients 16.98% with partial laryngectomy. The hyoid bones of all patients were examined histopathologically, and none of the 53 patients had hyoid bone invasion.Conclusion: Hyoid bone invasion is very rare in laryngeal cancers. One of the main factors preventing hyoid bone invasion is the natural preservation of anatomical barriers between the larynx and the hyoid bone. No hyoid bone invasion was observed in any patient in the present study. Hence, it is believed that hyoid bone can be preserve, especially in selected cases

References

  • Jones TM, De M, Foran B, Harrington K, Mortimore S. Laryngeal cancer: United Kingdom National Multidisciplinary guidelines. J Laryngol Otol 2016; 130(2):S75-S82.
  • Hanna J, Brauer PR, Morse E, Judson B, Mehra S. Is robotic surgery an option for early T-stage laryngeal cancer? Early nationwide results. Laryngoscope 2019; 24. [Epub ahead of print]
  • Hafız G, Başaran B, Ulusan M, Comoğlu S. A new extended supracricoid laryngectomy technique for tongue base and hyoid bone involvement: Crico-glosso- mandibulopexy technique. Kulak Burun Bogaz Ihtis Derg 2014; 24(3):181-4.
  • Timon CI, Gullane PJ, Brown D, Van Nostrand AW. Hyoid bone involvement by squamous cell carcinoma: Clinical and pathological features. Laryngoscope 1992; 102(5):515-20.
  • Spriano G, Mercante G, Anelli A, Cristalli G, Ferreli F. Lateral cervical approach for open laryngeal surgery: Technical notes. Head Neck 2019; 41(3):813-20.
  • Marchetta FC, Sako K, Murphy JB. The periosteum of the mandible and intraoral carcinoma. Am J Surg 1971; 122(6):711-3.
  • Gómez Serrano M, Iglesias Moreno MC, Gimeno Hernández J, Ortega Medina L, Martín Villares C, Poch Broto J. Cartilage invasion patterns in laryngeal cancer. Eur Arch Otorhinolaryngol 2016; 273(7):1863-9.
  • Pan Y, Hong Y, Liang Z, Zhuang W. Survival analysis of distant metastasis of laryngeal carcinoma: Analysis based on SEER database. Eur Arch Otorhinolaryngol. 2019; 276(1):193-201.
  • Ballenger JJ, Snow JB. Otorhinolaryngology head and neck surgery: 15th ed. Philadelphia: Lippincott Williams and Wilkins, 1996: 618.
  • Kirchner JA. Closure after supraglottic laryngectomy. Laryngoscope 1979; 89(8):1343-4.
  • Ogura JH. Surgical pathology of cancer of the larynx. Laryngoscope 1955; 65:867-926.
  • Suoglu Y, Guven M, Kiyak E, Enoz M. Significance of pre-epiglottic space invasion in supracricoid partial laryngectomy with cricohyoidopexy. J Laryngol Otol 2008; 122(6):623-7.
  • Dursun G, Keser R, Aktürk T, Akìner MN, Demireller A, Sak SD. The significance of pre-epiglottic space invasion in supraglottic laryngeal carcinomas. Eur Arch Otorhinolaryngol 1997; 254(1):110-2.
There are 13 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Neslihan Yaprak This is me

Publication Date January 1, 2020
Published in Issue Year 2020 Volume: 6 Issue: 2

Cite

Vancouver Yaprak N. Should Hyoid Bone Invasion be Included in the Prognostic Markers of Laryngeal Cancer? Larenks Kanserlerinde Hyoid Kemik İnvazyonu Prognostik Belirteçler İçerisinde Yer Almalı mı?. Akd Med J. 2020;6(2):286-8.