Review

Perinatal Transmission of Hepatitis B Virus

Volume: 25 Number: 3 September 30, 2016
Murat Afyon , Cumhur Artuk
TR EN

Perinatal Transmission of Hepatitis B Virus

Abstract

Perinatal transmission of hepatitis B virus (HBV) is the predominant mode of transmission in countries with a high prevalence of hepatitis B surface antigen carriage. Perinatal transmission can occur via three modalities: intrauterine transmission; transmission during delivery; and postpartum transmission and perinatal transmission results in a high frequency of chronic infection. Therefore, it is important to prevent perinatal transmission. At-birth prophylaxis with hepatitis B immunoglobulin (HBIG) and the first dose of the HBV vaccine can prevent transmission during delivery or in the postpartum period, but it has no effect on the intrauterine route of transmission. Due to the residual risk of perinatal transmission despite correct use of birth prophylaxis with HBIG and vaccine, other strategies (namely, antiviral drugs, HBIG to the mother, and mode of delivery) have been tested in several studies.  

Keywords

Pregnancy,hepatitis B virus,perinatal transmission,antiviral prophylaxis

References

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APA
Afyon, M., & Artuk, C. (2016). Perinatal Transmission of Hepatitis B Virus. Arşiv Kaynak Tarama Dergisi, 25(3), 304-318. https://doi.org/10.17827/aktd.237672
AMA
1.Afyon M, Artuk C. Perinatal Transmission of Hepatitis B Virus. Arşiv Kaynak Tarama Dergisi. 2016;25(3):304-318. doi:10.17827/aktd.237672
Chicago
Afyon, Murat, and Cumhur Artuk. 2016. “Perinatal Transmission of Hepatitis B Virus”. Arşiv Kaynak Tarama Dergisi 25 (3): 304-18. https://doi.org/10.17827/aktd.237672.
EndNote
Afyon M, Artuk C (September 1, 2016) Perinatal Transmission of Hepatitis B Virus. Arşiv Kaynak Tarama Dergisi 25 3 304–318.
IEEE
[1]M. Afyon and C. Artuk, “Perinatal Transmission of Hepatitis B Virus”, Arşiv Kaynak Tarama Dergisi, vol. 25, no. 3, pp. 304–318, Sept. 2016, doi: 10.17827/aktd.237672.
ISNAD
Afyon, Murat - Artuk, Cumhur. “Perinatal Transmission of Hepatitis B Virus”. Arşiv Kaynak Tarama Dergisi 25/3 (September 1, 2016): 304-318. https://doi.org/10.17827/aktd.237672.
JAMA
1.Afyon M, Artuk C. Perinatal Transmission of Hepatitis B Virus. Arşiv Kaynak Tarama Dergisi. 2016;25:304–318.
MLA
Afyon, Murat, and Cumhur Artuk. “Perinatal Transmission of Hepatitis B Virus”. Arşiv Kaynak Tarama Dergisi, vol. 25, no. 3, Sept. 2016, pp. 304-18, doi:10.17827/aktd.237672.
Vancouver
1.Murat Afyon, Cumhur Artuk. Perinatal Transmission of Hepatitis B Virus. Arşiv Kaynak Tarama Dergisi. 2016 Sep. 1;25(3):304-18. doi:10.17827/aktd.237672