Meme Kanserinde Epigenetik Tedavi

Onur Eroğlu

doi:10.17827/aktd.365260

EN TR

Meme Kanserinde Epigenetik Tedavi

Öz

Hem genetik hem de epigenetik değişikliklerle kanser ilerlemesi kontrol altına alınabilmektedir. Genetik değişimlerin geri dönüşümü imkansızken epigenetik değişimler geri dönüştürülebilir. Bu avantaj, önerilen epigenetik modifikasyonların terapi uygulamalarında tercih edilmesi gerektiğini göstermektedir. DNA metiltransferaz ve histon deasetilaz epigenetik terapi çalışmalarının birinci hedefi haline gelmiştir. Bazı DNA metilasyon ve histon deasetilasyon inhibitörleri anti kanser ilaçları olarak Amerika’da Gıda ve İlaç İdaresi tarafından onaylanmıştır. Bu nedenle, epigenetik hedeflerin kullanımları meme kanseri tedavisinde olumlu bir yaklaşım olarak büyük bir potansiyele sahip olduğuna inanılmaktadır.

Anahtar Kelimeler

Meme kanseri,epigenetik terapi,DNA metilasyon inhibitörleri,Histon deasetilasyon inhibitörleri

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Onur Eroğlu ^*
BİLECİK ŞEYH EDEBALİ ÜNİVERSİTESİ
0000-0002-3451-8540
Türkiye

Publication Date

September 30, 2018

Submission Date

December 13, 2017

Acceptance Date

February 15, 2018

Published in Issue

Year 2018 Volume: 27 Number: 3

DOI

https://doi.org/10.17827/aktd.365260

IZ

https://izlik.org/JA75PE86GE

AMA

1.Eroğlu O. Meme Kanserinde Epigenetik Tedavi. Arşiv Kaynak Tarama Dergisi. 2018;27(3):346-362. doi:10.17827/aktd.365260

This journal is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Meme Kanserinde Epigenetik Tedavi

Epigenetic Therapy in Breast Cancer

Abstract

Keywords

Meme Kanserinde Epigenetik Tedavi

Öz

Anahtar Kelimeler

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

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