Meme Kanserinde Epigenetik Tedavi

Onur Eroğlu

doi:10.17827/aktd.365260

EN TR

Meme Kanserinde Epigenetik Tedavi

Öz

Hem genetik hem de epigenetik değişikliklerle kanser ilerlemesi kontrol altına alınabilmektedir. Genetik değişimlerin geri dönüşümü imkansızken epigenetik değişimler geri dönüştürülebilir. Bu avantaj, önerilen epigenetik modifikasyonların terapi uygulamalarında tercih edilmesi gerektiğini göstermektedir. DNA metiltransferaz ve histon deasetilaz epigenetik terapi çalışmalarının birinci hedefi haline gelmiştir. Bazı DNA metilasyon ve histon deasetilasyon inhibitörleri anti kanser ilaçları olarak Amerika’da Gıda ve İlaç İdaresi tarafından onaylanmıştır. Bu nedenle, epigenetik hedeflerin kullanımları meme kanseri tedavisinde olumlu bir yaklaşım olarak büyük bir potansiyele sahip olduğuna inanılmaktadır.

Anahtar Kelimeler

Meme kanseri,epigenetik terapi,DNA metilasyon inhibitörleri,Histon deasetilasyon inhibitörleri

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Derleme

Yazarlar

Onur Eroğlu ^*
BİLECİK ŞEYH EDEBALİ ÜNİVERSİTESİ
0000-0002-3451-8540
Türkiye

Yayımlanma Tarihi

30 Eylül 2018

Gönderilme Tarihi

13 Aralık 2017

Kabul Tarihi

15 Şubat 2018

Yayımlandığı Sayı

Yıl 2018 Cilt: 27 Sayı: 3

DOI

https://doi.org/10.17827/aktd.365260

IZ

https://izlik.org/JA75PE86GE

APA

Eroğlu, O. (2018). Meme Kanserinde Epigenetik Tedavi. Arşiv Kaynak Tarama Dergisi, 27(3), 346-362. https://doi.org/10.17827/aktd.365260

AMA

1.Eroğlu O. Meme Kanserinde Epigenetik Tedavi. aktd. 2018;27(3):346-362. doi:10.17827/aktd.365260

Chicago

Eroğlu, Onur. 2018. “Meme Kanserinde Epigenetik Tedavi”. Arşiv Kaynak Tarama Dergisi 27 (3): 346-62. https://doi.org/10.17827/aktd.365260.

EndNote

Eroğlu O (01 Eylül 2018) Meme Kanserinde Epigenetik Tedavi. Arşiv Kaynak Tarama Dergisi 27 3 346–362.

IEEE

[1]O. Eroğlu, “Meme Kanserinde Epigenetik Tedavi”, aktd, c. 27, sy 3, ss. 346–362, Eyl. 2018, doi: 10.17827/aktd.365260.

ISNAD

Eroğlu, Onur. “Meme Kanserinde Epigenetik Tedavi”. Arşiv Kaynak Tarama Dergisi 27/3 (01 Eylül 2018): 346-362. https://doi.org/10.17827/aktd.365260.

JAMA

1.Eroğlu O. Meme Kanserinde Epigenetik Tedavi. aktd. 2018;27:346–362.

MLA

Eroğlu, Onur. “Meme Kanserinde Epigenetik Tedavi”. Arşiv Kaynak Tarama Dergisi, c. 27, sy 3, Eylül 2018, ss. 346-62, doi:10.17827/aktd.365260.

Vancouver

1.Onur Eroğlu. Meme Kanserinde Epigenetik Tedavi. aktd. 01 Eylül 2018;27(3):346-62. doi:10.17827/aktd.365260

Meme Kanserinde Epigenetik Tedavi

Epigenetic Therapy in Breast Cancer

Öz

Anahtar Kelimeler

Meme Kanserinde Epigenetik Tedavi

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

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