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Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları

Year 2019, , 580 - 585, 31.12.2019
https://doi.org/10.35414/akufemubid.570537

Abstract

Schiff
bazları analitik kimyada olduğu kadar boyar maddelerin üretiminde, bazı
ilaçların hazırlanmasında, elektronik endüstrisinde, plastik sanayiinde ve sıvı
kristal teknolojisi gibi çeşitli dallarda gittikçe artan öneme sahip
maddelerdir.
Bu çalışmada tiyazol tabanlı
Schiff bazı ile nikel, bakır ve çinko metal kompleksleri sentezlenmiştir.
Sentezlenen bileşiklerin yapıları element analizi
IR, 1H NMR, 13C NMR spektroskopik yöntemleriyle
aydınlatılmıştır. Bileşiklerin bakteri ve mantarlara karşı antimikrobiyal aktiviteleri
araştırılmıştır. Ni(II) ve Zn(II) komplekslerinin Staphylococcus aureus a karşı zayıf aktivite gösterdiği bulunmuştur.

Supporting Institution

Karamanoğlu Mehmetbey Üniversitesi

Project Number

30-M-16

Thanks

Bu çalışma Karamanoğlu Mehmetbey Üniversitesi Bilimsel Araştırma Projeleri Birimi tarafından 30-M-16 numaralı proje tarafından desteklenmiştir.

References

  • Abdou Saad El-Tabl , Fathey A. El-Saied, Winfried Plass, Ahmed Noman Al-Hakimi, 2008. Synthesis, spectroscopic characterization and biological activity of the metal complexes of the Schiff base derived from phenylaminoacetohydrazide and dibenzoylmethane, Spectrochimica Acta Part A 71, 90–99.
  • Agrawal, Y.K., 1979. Hydroxamic Acids and Their Metal Complexes. Russ. Chem. Res., 48 (10), 948.
  • Bekaroğlu, Ö., 1972. Koordinasyon Kimyası, İ.Ü. Kimya Fak., İstanbul.
  • Beyer, H., 1963. Organic Chemistry, p. 609-610, Verlag Harry Deutsch, Frankfurt / Main und Zurich.
  • Burger, K., 1973. Organic Reagents in Metal Analysis, Pergamon Press, New York.
  • Cukurovali, S. Gür and İ. Yilmaz, and C. Kazaz, 2006. Synthesis, antimicrobial and antifungal activity of some new thiazolylhydrazone derivatives containing 3-substituted cyclobutane ring”, European Journal of Medicinal Chemistry, 41(2), 201-207.
  • Dhar, D.B., and Taploo, C.C., 1982. Schiff bases and their applications. J. Scient. Ind. Res., 41 (8), 501.
  • Frust, A., 1963. Chemistry of Chelation of Cancer, p.105, CC Thomas, Llinois.
  • Gangadhar B. Bagihalli, Prakash Gouda Avaji, Sangamesh A. Patil, Prema S. Badami, 2008. Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases, European Journal of Medicinal Chemistry 43, 2639-2649.
  • Masoud, M.S., and Refaat, L.S., 1982. Synthesis and characterization of some nickel(II) Schiff-bases complexes. Trans. Met. Chem., 7, 315.
  • Meffin, P.J., Williams, R.L., Blaschke, R.F., and Rowland, M., 1977. Pharmaceutical salts, J. Pharm. Sci., 66, 135.
  • Metzler, D.E., and Snell, E. E., 1952. Some Transamination Reactions Involving Vitamin B61. J. Am. Chem. Soc., 74, 979.
  • Murthy, A.S.N., and Reddy, A.R., 1981. Electronic absorption spectroscopic studies of enolimine-ketoamine equilibria in Schiff-bases Proc. Indian Acad. Sci.(Chem. Sci.), 90, 519.
  • Pesavento, M., and Soldi, T., 1983. Spectrophotometric study and analytical applications of the complexes of copper(II) and zinc(II) with some sulphonated azo dyes. Analyst, 108, 1128-1134.
  • Sawhney, S.N., Arora, S.K., and Singh, J.N., 1980. Benzothiazole derivatives .10. Synthesis and anti-inflammatory activity of some 2-(5'-mercapto-substituted mercapto-1',3',4'-oxadıazol-2'-yl)benzothiazoles and 2-(4'-amino-5'-mercapto-1',2',4'-triazol-3'-yl)benzothiazole Indian J. Chem Section B-Organic Chemistry Including Medicinal Chemistry, 19, 5, 415.
  • Suzuki, N., Tanaka, Y., and Dohmori, R., 1979. Synthesis of anti-microbial agents .4. Synthesis and anti-microbial activities of imidazo[4,5-b][1,8]naphthyridine derivatives. Chem. Pharm. Bull., 27, 1.
  • Yilmaz, I., PhD Thesis, Firat University, 2002.
  • Yilmaz I ve Cukurovali, A., 2004. Cobalt(II), Copper(II), Nickel(II), and Zinc(II) Complexes of Naphthaldehyde Thiazolyl Hydrazones", Polish Journal of Chemistry, 78(5), 663-672.
  • Zishen, W., Huxia, W., Zhenhuan, Y., and Changhai, H., XXV. 1987. International Conference on Coordination Chemistry, Book of Abstracts’, p. 663.
Year 2019, , 580 - 585, 31.12.2019
https://doi.org/10.35414/akufemubid.570537

Abstract

Project Number

30-M-16

References

  • Abdou Saad El-Tabl , Fathey A. El-Saied, Winfried Plass, Ahmed Noman Al-Hakimi, 2008. Synthesis, spectroscopic characterization and biological activity of the metal complexes of the Schiff base derived from phenylaminoacetohydrazide and dibenzoylmethane, Spectrochimica Acta Part A 71, 90–99.
  • Agrawal, Y.K., 1979. Hydroxamic Acids and Their Metal Complexes. Russ. Chem. Res., 48 (10), 948.
  • Bekaroğlu, Ö., 1972. Koordinasyon Kimyası, İ.Ü. Kimya Fak., İstanbul.
  • Beyer, H., 1963. Organic Chemistry, p. 609-610, Verlag Harry Deutsch, Frankfurt / Main und Zurich.
  • Burger, K., 1973. Organic Reagents in Metal Analysis, Pergamon Press, New York.
  • Cukurovali, S. Gür and İ. Yilmaz, and C. Kazaz, 2006. Synthesis, antimicrobial and antifungal activity of some new thiazolylhydrazone derivatives containing 3-substituted cyclobutane ring”, European Journal of Medicinal Chemistry, 41(2), 201-207.
  • Dhar, D.B., and Taploo, C.C., 1982. Schiff bases and their applications. J. Scient. Ind. Res., 41 (8), 501.
  • Frust, A., 1963. Chemistry of Chelation of Cancer, p.105, CC Thomas, Llinois.
  • Gangadhar B. Bagihalli, Prakash Gouda Avaji, Sangamesh A. Patil, Prema S. Badami, 2008. Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases, European Journal of Medicinal Chemistry 43, 2639-2649.
  • Masoud, M.S., and Refaat, L.S., 1982. Synthesis and characterization of some nickel(II) Schiff-bases complexes. Trans. Met. Chem., 7, 315.
  • Meffin, P.J., Williams, R.L., Blaschke, R.F., and Rowland, M., 1977. Pharmaceutical salts, J. Pharm. Sci., 66, 135.
  • Metzler, D.E., and Snell, E. E., 1952. Some Transamination Reactions Involving Vitamin B61. J. Am. Chem. Soc., 74, 979.
  • Murthy, A.S.N., and Reddy, A.R., 1981. Electronic absorption spectroscopic studies of enolimine-ketoamine equilibria in Schiff-bases Proc. Indian Acad. Sci.(Chem. Sci.), 90, 519.
  • Pesavento, M., and Soldi, T., 1983. Spectrophotometric study and analytical applications of the complexes of copper(II) and zinc(II) with some sulphonated azo dyes. Analyst, 108, 1128-1134.
  • Sawhney, S.N., Arora, S.K., and Singh, J.N., 1980. Benzothiazole derivatives .10. Synthesis and anti-inflammatory activity of some 2-(5'-mercapto-substituted mercapto-1',3',4'-oxadıazol-2'-yl)benzothiazoles and 2-(4'-amino-5'-mercapto-1',2',4'-triazol-3'-yl)benzothiazole Indian J. Chem Section B-Organic Chemistry Including Medicinal Chemistry, 19, 5, 415.
  • Suzuki, N., Tanaka, Y., and Dohmori, R., 1979. Synthesis of anti-microbial agents .4. Synthesis and anti-microbial activities of imidazo[4,5-b][1,8]naphthyridine derivatives. Chem. Pharm. Bull., 27, 1.
  • Yilmaz, I., PhD Thesis, Firat University, 2002.
  • Yilmaz I ve Cukurovali, A., 2004. Cobalt(II), Copper(II), Nickel(II), and Zinc(II) Complexes of Naphthaldehyde Thiazolyl Hydrazones", Polish Journal of Chemistry, 78(5), 663-672.
  • Zishen, W., Huxia, W., Zhenhuan, Y., and Changhai, H., XXV. 1987. International Conference on Coordination Chemistry, Book of Abstracts’, p. 663.
There are 19 citations in total.

Details

Primary Language Turkish
Subjects Engineering
Journal Section Articles
Authors

İbrahim Yılmaz 0000-0002-9447-3065

Alaaddin Çukurovalı 0000-0002-8297-2350

Project Number 30-M-16
Publication Date December 31, 2019
Submission Date May 27, 2019
Published in Issue Year 2019

Cite

APA Yılmaz, İ., & Çukurovalı, A. (2019). Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 19(3), 580-585. https://doi.org/10.35414/akufemubid.570537
AMA Yılmaz İ, Çukurovalı A. Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. December 2019;19(3):580-585. doi:10.35414/akufemubid.570537
Chicago Yılmaz, İbrahim, and Alaaddin Çukurovalı. “Tiyazol Tabanlı Schiff Bazı Ve Metal Komplekslerinin Sentezi Ve Antimikrobiyal Aktivite Çalışmaları”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 19, no. 3 (December 2019): 580-85. https://doi.org/10.35414/akufemubid.570537.
EndNote Yılmaz İ, Çukurovalı A (December 1, 2019) Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 19 3 580–585.
IEEE İ. Yılmaz and A. Çukurovalı, “Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları”, Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, vol. 19, no. 3, pp. 580–585, 2019, doi: 10.35414/akufemubid.570537.
ISNAD Yılmaz, İbrahim - Çukurovalı, Alaaddin. “Tiyazol Tabanlı Schiff Bazı Ve Metal Komplekslerinin Sentezi Ve Antimikrobiyal Aktivite Çalışmaları”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 19/3 (December 2019), 580-585. https://doi.org/10.35414/akufemubid.570537.
JAMA Yılmaz İ, Çukurovalı A. Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2019;19:580–585.
MLA Yılmaz, İbrahim and Alaaddin Çukurovalı. “Tiyazol Tabanlı Schiff Bazı Ve Metal Komplekslerinin Sentezi Ve Antimikrobiyal Aktivite Çalışmaları”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, vol. 19, no. 3, 2019, pp. 580-5, doi:10.35414/akufemubid.570537.
Vancouver Yılmaz İ, Çukurovalı A. Tiyazol Tabanlı Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2019;19(3):580-5.


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