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Vanadium

Year 2014, Volume: 14 Issue: 2, 9 - 18, 01.08.2014

Abstract

Vanadium corrosion and oxidation resistant transition metal exhibits common oxidation states ranging from +2 to +5. Vanadium and vanadium compounds are used in production of nonferrous alloy steel, semiconductors, and photographic developing materials. Many vanadium compounds act as catalyst in many industrial process like production of sulfuric acid and many organic compounds. Foods are main source for humans and animals. VO31− ions predominate in extracellular body fluids whereas VO2+ ions are the most common intracellular form. Lungs absorb ionic and nonionic vanadium compounds, but the absorption of ionic compounds in gastrointestinal system is poor. Vanadium is presumably an essential trace element, however any disease has not been confirmed due to daily vanadium deficiency. Toxicity of vanadium compounds is low. Vanadium is not carcinogenic, but possibility of carcinogenic phenomenon should be considered. Elimination of excess vanadium from body is unnecessary because half-life of vanadium is low. In other words, treatment is supportive. Ascorbic acid and chelating deferoxamine and 4,5-dihydroxy-1,3-benzenedisülphonic acid compounds can be used against vanadium poisoning.© Afyon Kocatepe Üniversitesi

References

  • Arimoto R., Duce, A. Ray, B. J. Ellis, W. G. Cullen, J. D., Merrill, J. T. 1995, Trace elements in the atmosphere, J. Geophysical Res.: Atmospheres, 100, 1199–1213.
  • Barceloux, D. G. and Barceloux, D. 1999, Vanadium, Clin. Toxicol., 37, 265-278.
  • Bartholic, 1979, D. B., Preparation of FCC charge from residual fractions, Patent numarası: US4243514 A, USA.
  • Bauer, G., Güther, V., Hess, H., Otto, A., Roller, H., Roidl, O., Stattelberger, compounds, Chemistry, 38, 49-69. and vanadium Industrial Ullmann's Encyclopedia of
  • Biswajit Mukherjee, B., Patra, B., Mahapatra, S., Banerjee, P, Tiwari, A., Chatterjee, M., 2004, Vanadium—an element of atypical biological significance, Toxico. Lett., 150, 135–143.
  • Boden, G., Chen X., Ruiz J., van Rossum, G. D. V., Turco, S. 1996, Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus, Metabolism, 45, 1130–1135.
  • Byerrum, R. U., Eckardt, R.E., Hopkins, L.L., Libsch, J.F., Rostoker, W., Zenz, C., 1974, Vanadium, National Academy of Sciences, Washington DC, USA.
  • Cam M. C., Cros G. H., Serrano J. J., Lazaro R., McNeill J.H., 1993, Long-term effectiveness of oral vanadyl sulphate in streptozotocin-diabetic rates. Diabetologia, 36, 218–224.
  • Candura, S. M., Manzo, L., Marraccini, P., Coccini, T., Tonini, M., 1994, Investigation into vanadate-induced potentiation of smooth muscle contractility in the rabbit isolated ileum, Life Sci., 54, 237–244.
  • Cevik, S. 2001, Synthesis and characterization of new vanadium oxide phases imcorporating polyoxo ligands. PhD Thesis, Illinois Institute of Technology, Chicago, Illinois.
  • Cevik, S., Poyraz, M., Sarı, M. and Büyükgüngör, O. 2007, A novel three dimensional organic–inorganic hybrid based porous phase: synthesis and characterization of reduced oxovanadium pyromellitate, [VIV2O2(H2O)2(C6H2(COO)4)]. Journal of Chemical Crystallography, 37, 497–502.
  • Chaurand, P., Rose, J., Briois, V., Olivi, L., Hazemann, J.-L., Proux, O., Domas, J., Bottero, J.-Y., 2007, Environmental impacts of steel slag reused in road construction: A crystallographic and molecular (XANES) approach, J. Hazard. Mater., 139, 537–542.
  • Chen, Z. L. and Owens G., 2008, Trends in speciation analysis of vanadium in environmental samples and biological fluids—A review, Analytica Chimica Acta, 607, 1–14.
  • Crans, D. C., Smee, J. J., Gaidamauskas E. Yang, L. 2004, The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds, Chem. Rev., 104, 849–902.
  • Cruz, T. F., Morgan A., Min, W., 1995, In vitro and in vivo antineoplastic effects of orthovanadate, Mol. Cell. Biochem. 153, 161–166.
  • Dill, J. A., Lee, K. M., Mellinger, K. H., Bates, D. J., Burka, L. T., Roycroft, J. H., 2004, Lung Deposition and Clearance of Inhaled Vanadium Pentoxide in Chronically Exposed F344 Rats and B6C3F1 Mice, Toxico. Sci. 77, 6-18.
  • Dimond E. G., Caravaca J., Benchimol, A. 1963, Vanadium: excretion, toxicity, lipid effect in man. Am. J. Clin. Nutr.12,49–53.
  • Domingo, J. L., Llobet, J. M., Tomas, J. M, Corbella, J., 1986, Influence of chelating agents on the toxicity, distribution and excretion of vanadium in mice, J. Appl. Toxicol. 6, 337– 341.
  • Fawcett, J. P., Farquhar ,S. J., Thou, T., Shand, B. I., 1997, Oral vanadyl sulphate does not affect blood cells, viscosity or biochemistry in humans, Pharmacol. Toxicol., 80, 202–206.
  • Fine, S. A. and Kinsella, K. J., 1999, Compositions and methods for treatment for glucose metabolism disorders, Patent Numarası: US 6852760 B1, Akesis Pharmaceuticals, Inc., USA.
  • Goldfine, A. B., Somonson, D.C., Folli F., Patti, M.E., Kany, C. R., 1995, Metabolic effects of sodium metavanadate in humans dependent diabetes mellitus in vivo and in vitro studies, J. Clin. Endocrinol. Metab., 80, 3311–3320. non-insulin
  • Gomez, M., Domingo, J. L., Llobet, J. M., Paternain, J. L., 1988, Effectiveness of chelation therapy with time after acute vanadium intoxication J. Appl. Toxicol. 8, 439–444.
  • Goyer, R. A. and Clarkson, T. W. 1996, Toxic effects of metals. in The Basic Science of Poisons, (Ed. Klaassen, C. D.) Chapter 23, McGraw-Hill Health Professions Division, USA.
  • Gummow, B., 2011, Vanadium: environmental pollution and health effects, In: Nriagu, J. O., (ed.) Encyclopedia of Environmental Health, 628-636.
  • Hansen, T. V., Aaseth, J., Alexander, J., 1982, The effect of chelating agents on vanadium distribution in the rat body and on uptake by human erythrocytes, Arch. Toxicol, 50,195–202.
  • Harland, B.F., Harden-Williams B. A., 1994 Is vanadium of human nutritional importance yet? J. Am. Diet. Assoc., 94, 891-894.
  • Hodgson, A. B., Baskerville, R., Burke, L. M., Stear, S.J., Castelli, I. M., 2013, A–Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance, Br J Sports Med. 47, 247-248.
  • Ivancsits, S., Pilger, A., Diem, E., Schaffer, A., Rüdiger, H. W., 2002, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Mutation Research 519, 25– 35.
  • Janiszewska G., Lachowicz L., Jaskolski D., Gromadzinska E. , 1994, Vanadium inhibition of human parietal lobe ATPases. Int. J. Biochem. 26, 551–553.
  • Jones, M. M., Basinger, M. A.,1983, Chelate antidotes for sodium vanadate and vanadyl sulfate intoxication in mice, J. Toxicol. Environ. Health. 12, 749–756.
  • Kiviluoto M., 1980, Observations on the lungs of vanadium workers, Br. J. Ind .Med., 37, 363–366.
  • Kiviluoto M., Pyy L., Pakarinen A., 1981, Clinical laboratory results of vanadium exposed workers. Arch. Environ. Health. 36, 109–113.
  • Leonard, A., Gerber, G., B., 1994, Mutagenicity, carcinogenicity and teratogenicity of vanadium compounds Mut. Res. 317, 81–88.
  • Llobet JM, Colomina MT, Sirvent JJ, Domingo JL, Corbella J. 1993, Reproductive toxicity evaluation of vanadium in male mice, Toxicol. 80, 199–206.
  • Meish H. U. and Bielig H.J. Chemistry and biochemistry of vanadium, Basic Res. Cardiol., 75, 413–417.
  • Moskalyka, R.R. and Alfantazib, 2003, A.M., Processing of vanadium: a review, Miner. Eng., 16, 793–805.
  • Mukherjeea, B., Patraa, B., Mahapatraa, S., Banerjeea, P., Tiwarib, A. Chatterjeea, M. 2004 Vanadium—an element of atypical biological significance, Toxicol. Lett., 150, 135–143.
  • Nechay B. R., Mechanisms of action of vanadium, 1984, AnnuRev. Pharmacol. Toxicol., 24, 501–524.
  • Nielsen F. G. 1991, Nutritional requirements for boron, silicon, vanadium, nickel, and arsenic: Current knowledge and speculation, FASEB J. 5, 2661–2667.
  • Oyama, S. T. and Somorjai, G. A., 1990, Effect of structure in selective oxide catalysis: oxidation reactions of ethanol and ethane on vanadium oxide, J. Phys. Chem., 94, 5022–5028.
  • Proescher, F., Seil, H. A., Stillians, A. W, 1971, A contribution to the action of vanadium with particular reference to syphilis with a clinical contribution, Am. J. Syphilis, 1, 347–405.
  • Rehder, D., 1992, Structure and function of vanadium compounds in living organisms, Biometals, 5, 3-12.
  • Rehder, D. 1991, The Bioinorganic Chemistry of Vanadium, Angew. Chemie Int. Ed. Eng. 30, 148–167.
  • Sakurai, H., Yoshikawa, Y. and Yasui, H., 2008, Current state for the development of metallopharmaceutics and anti- diabetic metal complexes, Chem. Soc. Rev., 37, 2383-2392.
  • Słojewski M., 2011, Major and trace elements in lithogenesis, Cent. European J. Urol., 64(2), 58–61.
  • Stern, A., Yin, X., Tsang, S. S., Davison, A, Moon, J., 1993, Vanadium as a modulator of cellular regulatory cascades and oncogene expression, Biochem. Cell. Biol. 71, 103–112.
  • Wei C, Al Bayati MA, Culbertson MR, Rosenblatt LS, Hansen LD. 1982, Acute toxicity of ammonium metavanadate in mice. J. Toxicol. Environ. Health. 10, 673–687.
  • Yamaki, R. T., Paniago, E. B., Carvalho, S., Howarth, O. W. and Kam W., 1997, Interaction of N-hydroxyacetamide with vanadate in aqueous solution, J. Chem. Soc., Dalton Trans., 4817–4821.
  • Zhang, G., Zhao, Y., Liu, F., Ling, J., Lin, J., Zhang, C. 2013, Determination of essential and toxic elements in Cordyceps kyushuensis Kawam by inductively coupled plasma mass spectrometry, J. Pharmaceut. Biomed., 72, 172-176.

Vanadyum (021202) (9-18)

Year 2014, Volume: 14 Issue: 2, 9 - 18, 01.08.2014

Abstract

Vanadyum, çok farklı yükseltgenme basamağında bulunan, kolay yükseltgenmeyen, korozyona dayanıklı bir geçiş elementidir. Sert ve işlenebilir çelik, seramik, yarı iletken üretimi gibi birçok endüstriyel alanda vanadyum veya bileşikleri kullanılır. Sülfürik asit ve birçok organik bileşiğin üretimi gibi birçok alanda bileşikleri katalizör görevi görür. Canlılarda hücre dışı vücut sıvılarında VO31−, hücre içi vücut sıvılarında ise VO2+ formunda bulunur. Akciğerlerde çözünebilen vanadyum bileşiklerinin iyi absorbe edilmesine karşın vanadyum tuzları mide ve bağırsakta kolay emilime uğramazlar. Vanadyum muhtemelen temel bir eser element olmasına karşın vanadyum eksikliğinden dolayı herhangi bir hastalık insanlarda tespit edilememiştir. Genel olarak vanadyum bileşiklerinin toksisitesi düşüktür. Vanadyum kanserojen değildir, ancak kanserojen olma olasılığı göz önüne alınmalıdır. Yiyecekler, canlılar için esas vanadyum kaynağıdır. Genellikle vücuttaki vanadyumun fazlasını ortadan kaldırmak için yapılan önlemler gereksizdir çünkü vücutta vanadyum fazla kalmaz. Yani tedaviler destekleyicidir. Askorbik asit ve şelat oluşturucu zehirlenmesine karşı kullanılabilir. deferoksamin ve 4,5-dihidroksi-1,3-benzendisülfonik asit bileşikleri vanadyum

References

  • Arimoto R., Duce, A. Ray, B. J. Ellis, W. G. Cullen, J. D., Merrill, J. T. 1995, Trace elements in the atmosphere, J. Geophysical Res.: Atmospheres, 100, 1199–1213.
  • Barceloux, D. G. and Barceloux, D. 1999, Vanadium, Clin. Toxicol., 37, 265-278.
  • Bartholic, 1979, D. B., Preparation of FCC charge from residual fractions, Patent numarası: US4243514 A, USA.
  • Bauer, G., Güther, V., Hess, H., Otto, A., Roller, H., Roidl, O., Stattelberger, compounds, Chemistry, 38, 49-69. and vanadium Industrial Ullmann's Encyclopedia of
  • Biswajit Mukherjee, B., Patra, B., Mahapatra, S., Banerjee, P, Tiwari, A., Chatterjee, M., 2004, Vanadium—an element of atypical biological significance, Toxico. Lett., 150, 135–143.
  • Boden, G., Chen X., Ruiz J., van Rossum, G. D. V., Turco, S. 1996, Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus, Metabolism, 45, 1130–1135.
  • Byerrum, R. U., Eckardt, R.E., Hopkins, L.L., Libsch, J.F., Rostoker, W., Zenz, C., 1974, Vanadium, National Academy of Sciences, Washington DC, USA.
  • Cam M. C., Cros G. H., Serrano J. J., Lazaro R., McNeill J.H., 1993, Long-term effectiveness of oral vanadyl sulphate in streptozotocin-diabetic rates. Diabetologia, 36, 218–224.
  • Candura, S. M., Manzo, L., Marraccini, P., Coccini, T., Tonini, M., 1994, Investigation into vanadate-induced potentiation of smooth muscle contractility in the rabbit isolated ileum, Life Sci., 54, 237–244.
  • Cevik, S. 2001, Synthesis and characterization of new vanadium oxide phases imcorporating polyoxo ligands. PhD Thesis, Illinois Institute of Technology, Chicago, Illinois.
  • Cevik, S., Poyraz, M., Sarı, M. and Büyükgüngör, O. 2007, A novel three dimensional organic–inorganic hybrid based porous phase: synthesis and characterization of reduced oxovanadium pyromellitate, [VIV2O2(H2O)2(C6H2(COO)4)]. Journal of Chemical Crystallography, 37, 497–502.
  • Chaurand, P., Rose, J., Briois, V., Olivi, L., Hazemann, J.-L., Proux, O., Domas, J., Bottero, J.-Y., 2007, Environmental impacts of steel slag reused in road construction: A crystallographic and molecular (XANES) approach, J. Hazard. Mater., 139, 537–542.
  • Chen, Z. L. and Owens G., 2008, Trends in speciation analysis of vanadium in environmental samples and biological fluids—A review, Analytica Chimica Acta, 607, 1–14.
  • Crans, D. C., Smee, J. J., Gaidamauskas E. Yang, L. 2004, The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds, Chem. Rev., 104, 849–902.
  • Cruz, T. F., Morgan A., Min, W., 1995, In vitro and in vivo antineoplastic effects of orthovanadate, Mol. Cell. Biochem. 153, 161–166.
  • Dill, J. A., Lee, K. M., Mellinger, K. H., Bates, D. J., Burka, L. T., Roycroft, J. H., 2004, Lung Deposition and Clearance of Inhaled Vanadium Pentoxide in Chronically Exposed F344 Rats and B6C3F1 Mice, Toxico. Sci. 77, 6-18.
  • Dimond E. G., Caravaca J., Benchimol, A. 1963, Vanadium: excretion, toxicity, lipid effect in man. Am. J. Clin. Nutr.12,49–53.
  • Domingo, J. L., Llobet, J. M., Tomas, J. M, Corbella, J., 1986, Influence of chelating agents on the toxicity, distribution and excretion of vanadium in mice, J. Appl. Toxicol. 6, 337– 341.
  • Fawcett, J. P., Farquhar ,S. J., Thou, T., Shand, B. I., 1997, Oral vanadyl sulphate does not affect blood cells, viscosity or biochemistry in humans, Pharmacol. Toxicol., 80, 202–206.
  • Fine, S. A. and Kinsella, K. J., 1999, Compositions and methods for treatment for glucose metabolism disorders, Patent Numarası: US 6852760 B1, Akesis Pharmaceuticals, Inc., USA.
  • Goldfine, A. B., Somonson, D.C., Folli F., Patti, M.E., Kany, C. R., 1995, Metabolic effects of sodium metavanadate in humans dependent diabetes mellitus in vivo and in vitro studies, J. Clin. Endocrinol. Metab., 80, 3311–3320. non-insulin
  • Gomez, M., Domingo, J. L., Llobet, J. M., Paternain, J. L., 1988, Effectiveness of chelation therapy with time after acute vanadium intoxication J. Appl. Toxicol. 8, 439–444.
  • Goyer, R. A. and Clarkson, T. W. 1996, Toxic effects of metals. in The Basic Science of Poisons, (Ed. Klaassen, C. D.) Chapter 23, McGraw-Hill Health Professions Division, USA.
  • Gummow, B., 2011, Vanadium: environmental pollution and health effects, In: Nriagu, J. O., (ed.) Encyclopedia of Environmental Health, 628-636.
  • Hansen, T. V., Aaseth, J., Alexander, J., 1982, The effect of chelating agents on vanadium distribution in the rat body and on uptake by human erythrocytes, Arch. Toxicol, 50,195–202.
  • Harland, B.F., Harden-Williams B. A., 1994 Is vanadium of human nutritional importance yet? J. Am. Diet. Assoc., 94, 891-894.
  • Hodgson, A. B., Baskerville, R., Burke, L. M., Stear, S.J., Castelli, I. M., 2013, A–Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance, Br J Sports Med. 47, 247-248.
  • Ivancsits, S., Pilger, A., Diem, E., Schaffer, A., Rüdiger, H. W., 2002, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Mutation Research 519, 25– 35.
  • Janiszewska G., Lachowicz L., Jaskolski D., Gromadzinska E. , 1994, Vanadium inhibition of human parietal lobe ATPases. Int. J. Biochem. 26, 551–553.
  • Jones, M. M., Basinger, M. A.,1983, Chelate antidotes for sodium vanadate and vanadyl sulfate intoxication in mice, J. Toxicol. Environ. Health. 12, 749–756.
  • Kiviluoto M., 1980, Observations on the lungs of vanadium workers, Br. J. Ind .Med., 37, 363–366.
  • Kiviluoto M., Pyy L., Pakarinen A., 1981, Clinical laboratory results of vanadium exposed workers. Arch. Environ. Health. 36, 109–113.
  • Leonard, A., Gerber, G., B., 1994, Mutagenicity, carcinogenicity and teratogenicity of vanadium compounds Mut. Res. 317, 81–88.
  • Llobet JM, Colomina MT, Sirvent JJ, Domingo JL, Corbella J. 1993, Reproductive toxicity evaluation of vanadium in male mice, Toxicol. 80, 199–206.
  • Meish H. U. and Bielig H.J. Chemistry and biochemistry of vanadium, Basic Res. Cardiol., 75, 413–417.
  • Moskalyka, R.R. and Alfantazib, 2003, A.M., Processing of vanadium: a review, Miner. Eng., 16, 793–805.
  • Mukherjeea, B., Patraa, B., Mahapatraa, S., Banerjeea, P., Tiwarib, A. Chatterjeea, M. 2004 Vanadium—an element of atypical biological significance, Toxicol. Lett., 150, 135–143.
  • Nechay B. R., Mechanisms of action of vanadium, 1984, AnnuRev. Pharmacol. Toxicol., 24, 501–524.
  • Nielsen F. G. 1991, Nutritional requirements for boron, silicon, vanadium, nickel, and arsenic: Current knowledge and speculation, FASEB J. 5, 2661–2667.
  • Oyama, S. T. and Somorjai, G. A., 1990, Effect of structure in selective oxide catalysis: oxidation reactions of ethanol and ethane on vanadium oxide, J. Phys. Chem., 94, 5022–5028.
  • Proescher, F., Seil, H. A., Stillians, A. W, 1971, A contribution to the action of vanadium with particular reference to syphilis with a clinical contribution, Am. J. Syphilis, 1, 347–405.
  • Rehder, D., 1992, Structure and function of vanadium compounds in living organisms, Biometals, 5, 3-12.
  • Rehder, D. 1991, The Bioinorganic Chemistry of Vanadium, Angew. Chemie Int. Ed. Eng. 30, 148–167.
  • Sakurai, H., Yoshikawa, Y. and Yasui, H., 2008, Current state for the development of metallopharmaceutics and anti- diabetic metal complexes, Chem. Soc. Rev., 37, 2383-2392.
  • Słojewski M., 2011, Major and trace elements in lithogenesis, Cent. European J. Urol., 64(2), 58–61.
  • Stern, A., Yin, X., Tsang, S. S., Davison, A, Moon, J., 1993, Vanadium as a modulator of cellular regulatory cascades and oncogene expression, Biochem. Cell. Biol. 71, 103–112.
  • Wei C, Al Bayati MA, Culbertson MR, Rosenblatt LS, Hansen LD. 1982, Acute toxicity of ammonium metavanadate in mice. J. Toxicol. Environ. Health. 10, 673–687.
  • Yamaki, R. T., Paniago, E. B., Carvalho, S., Howarth, O. W. and Kam W., 1997, Interaction of N-hydroxyacetamide with vanadate in aqueous solution, J. Chem. Soc., Dalton Trans., 4817–4821.
  • Zhang, G., Zhao, Y., Liu, F., Ling, J., Lin, J., Zhang, C. 2013, Determination of essential and toxic elements in Cordyceps kyushuensis Kawam by inductively coupled plasma mass spectrometry, J. Pharmaceut. Biomed., 72, 172-176.
There are 49 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Sabri Çevik This is me

Publication Date August 1, 2014
Submission Date August 8, 2015
Published in Issue Year 2014 Volume: 14 Issue: 2

Cite

APA Çevik, S. (2014). Vanadyum (021202) (9-18). Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 14(2), 9-18.
AMA Çevik S. Vanadyum (021202) (9-18). Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. August 2014;14(2):9-18.
Chicago Çevik, Sabri. “Vanadyum (021202) (9-18)”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 14, no. 2 (August 2014): 9-18.
EndNote Çevik S (August 1, 2014) Vanadyum (021202) (9-18). Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 14 2 9–18.
IEEE S. Çevik, “Vanadyum (021202) (9-18)”, Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, vol. 14, no. 2, pp. 9–18, 2014.
ISNAD Çevik, Sabri. “Vanadyum (021202) (9-18)”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 14/2 (August 2014), 9-18.
JAMA Çevik S. Vanadyum (021202) (9-18). Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2014;14:9–18.
MLA Çevik, Sabri. “Vanadyum (021202) (9-18)”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, vol. 14, no. 2, 2014, pp. 9-18.
Vancouver Çevik S. Vanadyum (021202) (9-18). Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2014;14(2):9-18.