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Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery

Year 2016, Volume: 16 Issue: 1, 68 - 75, 30.04.2015

Fulya Taktak

https://doi.org/10.5578/fmbd.26306
Cited By: 4

Abstract

In this study, poly(2‐dimethylamino)ethyl methacrylate (PDMAEMA)    gels were prepared via in situ
polymerization reaction. Synthesized hydrogel was characterized with FTIR spectroscopy and SEM. The
pH‐ and temperature dependentswelling / deswelling behavior was investigated. The hydrogelshowed
highest value of swelling at pH 2. The rising temperature led to a decrease in swelling ratio due to the
fact that hydrophobic interactions between polymer segments become dominant. Furthermore, it was
observed that PDMAEMA hydrogel exhibited rapid deswelling rate in response to temperature and pH.
The drug release profile of PDMAEMA hydrogel has been reported by using Ibuprofen as a model drug.

Keywords

Hydrogel Controlled drug delivery Rapid response Deswelling

Year 2016, Volume: 16 Issue: 1, 68 - 75, 30.04.2015

Fulya Taktak

https://doi.org/10.5578/fmbd.26306
Cited By: 4

Abstract

There are 0 citations in total.

Details

Subjects Engineering
Journal Section Articles
Authors

Fulya Taktak

Publication Date April 30, 2015
Submission Date March 18, 2016
Published in Issue Year 2016 Volume: 16 Issue: 1

Cite

APA Taktak, F. (2015). Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 16(1), 68-75. https://doi.org/10.5578/fmbd.26306
AMA Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. April 2015;16(1):68-75. doi:10.5578/fmbd.26306
Chicago Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16, no. 1 (April 2015): 68-75. https://doi.org/10.5578/fmbd.26306.
EndNote Taktak F (April 1, 2015) Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16 1 68–75.
IEEE F. Taktak, “Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery”, Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, vol. 16, no. 1, pp. 68–75, 2015, doi: 10.5578/fmbd.26306.
ISNAD Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16/1 (April 2015), 68-75. https://doi.org/10.5578/fmbd.26306.
JAMA Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2015;16:68–75.
MLA Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, vol. 16, no. 1, 2015, pp. 68-75, doi:10.5578/fmbd.26306.
Vancouver Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2015;16(1):68-75.

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