Which Factors Affect the Functional Situation and Quality of Life in Patients with Ankylosing Spondylitis?

Abstract

Objectives: This study was performed to determine the possible predictive factors affecting the functional situation and quality of life in patients with ankylosing spondylitis (AS).

Materials and Methods: A total of 88 volunteer Turkish patients with AS were included in the study. We evaluated the Bath AS Functional Index (BASFI), Bath AS Disease Activity Index (BASDAI), Bath AS Metrology Index (BASMI) and AS Quality of Life Questionnaire (ASQoL) in patients. The ages, genders, levels of education, morning stiffness duration, smoking statuses, statues of doing the home exercises instructed were interrogated and mobility measurements of patients were performed and all of these values were recorded.

Results: BASFI was found to be correlated with smoking (p=0.019), morning stiffness (p=0.001), BMI (p=0.020), exercise (p=0.002), BASMI (p<0.001) and BASDAI (p<0.001). According to the categorical regression, BASDAI (Beta=0.574, p<0.001) was independently associated with the BASFI score.  ASQoL was found to have correlation with the level of education (p=0.030), smoking (p=0.049), morning stiffness (p=0.004) and exercise (p=0.007), BASDAI (p<0.001) and BASFI (p<0.001). It was found that the effect of BASFI was significant on the ASQoL(p=0.007).

Conclusion:  Even though the duration of the disease appears to be an unchangeable factor, smoking, duration of morning stiffness, the compliance with home-based exercise program and mobility measurements appear to be relatively changeable factors. Therefore, we believe that specialists who follow patients with AS can influence quality of life and functions of the patients by educating and inspiring them at every visit.    

Keywords

• Ankylosing spondylitis,Bath Ankylosing Spondylitis Metrology Index,Bath Ankylosing Spondylitis Functional Index,Bath Ankylosing Spondylitis Disease Activity Index,Ankylosing Spondylitis Quality of Life Questionnair

Ankilozan Spondilit Hastalarında Yaşam Kalitesini ve Fonksiyonel Durumu Hangi Faktörler Etkiler?

Öz

Giriş: Bu çalışma, Ankilozan spondilit (AS) hastalarında fonksiyonel durumu ve yaşam kalitesini etkileyen olası faktörleri belirlemek amacıyla yapıldı.

Materyal ve Metot: Çalışmaya AS'li toplam 88 adet gönüllü Türk hasta dahil edildi. Hastalarda Bath AS Fonksiyonel İndeks (BASFI), Bath AS Hastalık Aktivite İndeksi (BASDAI), Bath AS Metrology İndeksi (BASMI) ve AS Yaşam Kalitesi Anketi (ASQoL) değerlendirildi. Yaş, cinsiyet, eğitim düzeyi, sabah tutukluğu süresi, sigara içme durumu, evde egzersiz yapma durumları sorgulandı ve mobilite ölçümleri yapıldı ve bunlar kaydedildi. 

Bulgular: BASFI skoru sigara içme (p=0,019), egzersiz (p=0,002), sabah tutukluğu (p=0,001), vücud kütle indeksi (p=0,020), BASMI (p0,001) ve BASDAI (p0,001) ile korele bulundu. Kategorik regresyon analizine göre ise BASDAI BASFI skoru ile ilişkili bulundu (:0.574, p0,001). ASQoL ise sabah tutukluğu (p=0,004), eğitim durumu (p=0,030), sigara içme (p=0,049), egzersiz (p=0,007), BASDAI (p0,001) ve BASFI (p0,001) korele bulundu. ASQoL üzerinde BASFI’nin belirgin etkisi olduğu saptandı (p=0,007).

Sonuç: Hastalık süresi değiştirilemediği halde, sigara içme, sabah tutukluğunun süresi, evde egzersiz programına uyum ve hareketlilik ölçümleri nispeten değiştirilebilir faktörler gibi gözükmektedir. Bu nedenle, AS'li hastaları takip eden hekimlerin her ziyarette, bu konularda eğitim vererek ve bunu vurgulayarak hastaların yaşam kalitelerini ve fonksiyonlarını etkileyebileceklerine inanıyoruz.

Anahtar Kelimeler

• Ankilozan spondilit,Bath Ankilozan Spondilit Metroloji Indeksi,Bath Ankilozan Spondilit Fonksiyonel İndeks,Bath Ankilozan Spondilit Hastalık Aktivite İndeksi,Ankilozan Spondilit Yaşam Kalitesi Anketi

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