Diyabetik Retinopatisi Olmayan Tip 1 Diyabet Olgularında Retinal Mikrovasküler Yapıların İncelenmesi

Year 2018, , 628 - 636, 27.12.2018

Nagihan Uğurlu , Ayşe Güzin Taşlıpınar Fatma Yülek Didem Özdemir Reyhan Ersoy Bekir Çakır

https://doi.org/10.17098/amj.501136

Abstract

Amaç: Sunulan çalışmanın amacı retinopati tespit edilmemiş tip 1 diyabet olgularında, optik koherens

tomografi anjiyografi (OCTA) bulgularının değerlendirilmesidir.

Materyal ve Metot: Çalışmaya 11 tip 1 diyabet olgusunun 17 gözü ve 18 sağlıklı gönüllü olgunun 36 gözü

dahil edildi. Optik koherens tomografi anjiyografi görüntüleri, mikrovasküler değişikliklerin varlığı

açısından değerlendirildi ve yüzeysel kapiller pleksus (SKP) ve derin kapiller pleksus (DKP) seviyelerinde

foveal avasküler zone (FAZ) alanı ve vasküler densite (VD) ölçümleri yapıldı.

Bulgular: Optik Koherens Tomografi Anjiyografi incelemelerinde, 11 tip 1 diyabet olgusunun 7’sinde

mikrovasküler değişiklikler izlendi. Diyabetik grup ve kontrol grubu arasında SKP ve DKP seviyelerinde

yapılan faz ölçümlerinde anlamlı bir fark izlenmedi (sırasıyla p=0,647, p=0,874). Diyabetik grup ve kontrol

grubu arasında SKP ve DKP seviyelerinde yapılan VD ölçümleri arasında da anlamlı bir fark yoktu (p>0,05).

Sonuç: Klinik olarak diyabetik retinopati tanısı almamış diyabetik olgularda, retinal mikrovasküler yapıda

harabiyet gelişebilir. Optik koherens tomografi anjiyografi, erken evrede gelişen mikrovasküler bulguların

tanınmasında faydalı olan, hızlı, girişimsel olmayan ve güvenli bir görüntüleme yöntemidir.

Keywords

Tip 1 diabetes mellitus, diyabetik retinopati, optik koherens tomografi

Evaluation of Retinal Microvascular Structures in Type 1 Diabetic Patients without Diabetic Retinopathy

Abstract

Objectives:
The aim of the present study is to evaluate the optical coherence tomography
angiography (OCTA) images in patients with type 1 diabetes who have not been
diagnosed with retinopathy.

Materials
and Methods: The study included 17 eyes of 11
patients with type 1 diabetes and 36 eyes of 18 healthy volunteers. Optical
coherence tomography angiography images were evaluated for the presence of
microvascular changes and measurement of foveal avascular zone (FAZ) area and
vessel density (VD) measurements in the superficial capillary plexus (SCP) and
deep capillary plexus (DCP) were performed.

Results:
Optical coherence tomography angiography revealed microvascular changes in 7 of
11 type 1 diabetes cases. There was no significant difference between the FAZ
measurements between the diabetic group and the control group at the SCP and
DCP levels (p=0,647, p=0,874 respectively). There was also no significant
difference in VD measurements between the diabetic group and the control group
(p> 0.05).
Conclusion: In diabetic patients who
are not clinically diagnosed with diabetic retinopathy, retinal microvascular
damage may occur. Optical coherence tomography angiography is a rapid,
noninvasive, and safe imaging modality that is useful in the recognition of
microvascular findings that develop at an early stage.

Keywords

Type 1 diabetes mellitus, diabetic retinopathy, optical coherence tomography

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