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Evaluation of Risk Factors for Erectile Dysfunction in Diabetic Men

Year 2015, Volume: 15 Issue: 2, - , 02.05.2015
https://doi.org/10.17098/amj.66012

Abstract

Objectives: Erectile Dysfunction (ED) is sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual performance. ED is three times more frequent in diabetics. ED is associated with a reduced quality of life in diabetics. Also regarding the impact of ED on quality of life detection of the factors that are associated with ED is important to better management of the disease. In our study we aimed evaluate risk factors for erectile dysfunction in diabetic men.   

Materials and Method: A cross sectional study was carried out in type 2 patients who attended the outpatient clinic of Diabetes Kartal Training and Research hospital. Between the 1th July and 15th July, 80 consecutive patients were included to the study. According to the exclusion criterias, 65 diabetic patients were included. Control group is constituted by age matched 40 non diabetic patients who attended the family medicine and internal medicine outpatient clinics. All patients filled out a form which includes socio-demographic characteristics. All patients’ blood pressure, waist circumference, body mass index (BMİ) was measured. HbA1c, lipid profile, urea, creatinine and complete blood count were obtained. In all patients, erectile dysfunction was questioned with International Index of Erectile Function questionnaire (IIEF).

Results: In diabetic patients, the prevalence of erectile dysfunction was 76.9 %, in control group it was 37.5 %. The difference was statistically significant (p<0,001). Moreover in diabetics severe form of erectile dysfunction was mostly seen. In diabetics to identify independent predictors of ED multivariate logistic regression analysis was used. As a result, office systolic blood pressure > 130 mm Hg which was measured in outpatient clinic (p = 0,006),hyperlipidemia history (p = 0,008), waist circumference (p= 0,015), heart disease history (p = 0,025), HbA1c (p = 0,025) and triglyceride levels (p = 0,030) and diuretic use (p = 0,039) were significantly and independently associated with ED.

Conclusion: Our study results support that ED is more common in diabetic men than normal population. Abdominal obesity, hyperlipidemia and coronary heart disease associated with diabetes are risk factors for ED. Regarding the impact of ED on quality of life; we conclude that men with diabetes who have risk factors for ED should be assessed routinely.


 

References

  • NIH consensus development panel on impotence. JAMA 1993;270:83-90.
  • Sharifi F, Asghari M, Jaberi Y, et al. Independent Predictors of Erectile Dysfunction in Type 2 Diabetes Mellitus: Is It TrueWhat They Say about Risk Factors? ISRN Endocrinology 2012;2 (doi:10.5402/2012/502353).
  • İnal G. Erektil disfonksiyon ve diyabet. Androloji Bülteni 2005;20:1-3.
  • Yamasaki H, Ogawa K, Sasaki H, et al. Prevalence and risk factors of erectile dysfunction in Japanese men with type 2 diabetes. Diabetes Res Clin Pract 2004;66 (Suppl-1):173-7.
  • Kendirci M, Kadıoğlu A. Diyabet ve erektil disfonksiyon. Aktüel Tıp Diyabet Forumu 2002;7:34-43.
  • De Berardis G, Franciosi M, Belfiglio M, et al. Erectile dysfunction and quality of life in type 2 diabetic patients: A serious problem too often overlooked. Diabetes Care 2002;25:284-91.
  • Malavige LS, Levy JC. Erectile dysfunction in diabetes mellitus. J Sex Med 2009;6:1232-47.
  • Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrik I, Mishra A. The International Index of Erectile Function (IIEF). A multidimensional scale for assessment of erectile dysfunction. Urology 1997;49:822-36.
  • Kamenov ZA. A Comprehensive Review of Erectile Dysfunction in Men with Diabetes. Exp Clin Endocrinol Diabetes 2015;123:141-58.
  • Sasaki H, Yamasaki H, Ogawa K et al. Prevalance and risk factors of erectile dysfunction in Japanese diabetics. Diabetes Researh and Clinical Practice 2005;70:81-9.
  • Goyal A, Singh P, Ahuja A. Prevalence and Severity of Erectile Dysfunction as Assessed by IIEF-5 in North Indian Type 2 Diabetic Males and Its Correlation with Variables. J Clin Diagn Res 2013;7:2936-8.
  • Sargın M, Sargın H, Türkbörü Ü, Alp R. Prevalence and risk factors of erectile dysfunction in Type 2 diabetic men: A hospital based study. Endokrinolojide Yönelişler 2004;13:128-30.
  • Giugliano F, Maiorino M, Bellastella G, Gicchino M, Giugliano D, Espoksito K. Determinants of erectile dysfunction in type 2 diabetes. Int J Impot Res 2010;22:204-9. 14. Mutagaywa RK, Lutale J, Aboud M, Kamala associated factors among diabetic men attending diabetic clinic at Muhimbili National Hospital in Dar-es-Salaam, Tanzania. Pan Afr Med J 2014;26:227. BA.
  • Prevalence of erectile dysfunction and
  • Cander S, Coban S, Altuner S et al. Prevalence and correlates of erectile dysfunction in type 2 diabetes mellitus: a cross-sectional single-center study among Turkish patients. Metab Syndr Relat Disord 2014;12:324-9.
  • Kalter-Leibovici O, Wainstein J, Ziv A et al. Clinical, socioeconomic and lifestyle parameters associated with erectile dysfunction among diabetic men. Diabetes Care 2005;28:1739-44.
  • Ahmed I, Aamir Au, Anwar E, Ali SS, Ali A, Ali A. Erectile dysfunction and type 2 diabetes mellitus in northern Pakistan. J Pak Med Assoc 2013;63:1486-90.
  • Akkus E, Kadioglu A, Esen A et al. Prevalence and correlates of erectile dysfunction in Turkey: a population based study. Eur Urol 2002;41:298-304.
  • Al-Hunayan A, Al-Mutart, Kehinde E. et al. The prevalence and predictors of erectile dysfunction in men with newly diagnosed with Type 2 diabetes mellitus. BJU International 2007;99:130-4
  • Bal K, Oder M, Sahin AS et al. Prevalence of metabolic syndrome and its association with erectile dysfunction among urologic patients: metabolic backgrounds of erectile dysfunction. Urology 69:356-60.
  • Janiszewski PM, Janssen I, Ross R. Abdominal obesity and physical inactivity are associated with erectile dysfunction independent of body mass index. J Sex Med 2009;6:1990-8.
  • Harris MI, Klein R, Welborn TA, Knuiman MW. Onset of NIDDM occurs at least 4-7 yr before clinical diagnosis. Diabetes Care 1992;15:815-9.

Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi

Year 2015, Volume: 15 Issue: 2, - , 02.05.2015
https://doi.org/10.17098/amj.66012

Abstract

Amaç: Erektil disfonksiyon, cinsel birleşme için gerekli olan penil ereksiyona ulaşmakta ve sürdürmekte yetersizlik olarak tanımlanır. Diyabetik hastalarda erektil disfonksiyon (ED) normal populasyona göre 3 kat daha sık görülmektedir. Diyabetli erkeklerde erektil disfonksiyonun eşlik etmesi yaşam kalitesinde azalmaya neden olmaktadır. Bu nedenle diyabetli erkeklerde erektil disfonksiyon risk faktörlerini saptamak hastalığın yönetimi için önem arz etmektedir. Bu çalışmada diyabeti olan erkeklerde erektil disfonksiyon risk faktörlerini incelemek istedik.

Materyal ve Metot: Çalışmaya Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Diyabet Polikliniği tarafından takip edilen 1 Temmuz – 15 Temmuz 2012 tarihleri arasında poliklinik başvurusu yapan tip 2 diyabeti olan ardışık 80 hasta alındı. Dışlanma kriterlerine göre hastalar değerlendirildi ve 65 hasta çalışmaya dahil edildi. Kontrol grubu, Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi dahiliye ve aile hekimliği polikliniklerine başvuran, yaş açısından çalışma grubuyla eşleştirilmiş, diyabeti olmayan 40 erkek hastadan oluşturuldu. Çalışmaya alınan tüm hastalara sosyodemografik özelliklerini belirleyici sorular içeren bir anket formu doldurtuldu. Tüm katılımcıların kan basıncı, bel çevresi, boyu ve vücut ağırlığı ölçüldü, beden kitle indeksi (BKİ) hesaplandı. Tam kan sayımı, HbA1c düzeyi, lipid profili, üre, kreatinin testleri yapıldı. Erektil disfonksiyon ereksiyon işlevi uluslararası değerlendirme formu (İEFF) ile sorgulandı.

Bulgular: ED sıklığı diyabetik grupta % 76,9 ve kontrol grubunda % 37,5 olarak bulundu. Aradaki fark istatistiki olarak anlamlıydı (p<0,001). Ayrıca diyabetik grupta ED kontrol grubuna göre daha ağır formlarda ortaya çıkıyordu. Diyabetik hastalarda ED sıklığı ile ilişkili faktörleri incelemek için lojistik regresyon analizi kullanılmıştır. Sonuç olarak diyabetik hastalarda ED varlığı ve poliklinikte yapılan ofis ölçümünde sistolik tansiyonun >130 mmHg olması (p = 0,006), hiperlipidemi öyküsü (p = 0,008), bel çevresi (p= 0,015), kalp hastalığı öyküsü (p = 0,025), HbA1c seviyesi (p = 0,025), trigliserit düzeyi (p = 0,030), ve diüretik kullanımı (p = 0,039) ile arasında anlamlı derecede ilişki olduğu saptandı.

Sonuç: Çalışmamızın sonuçları diyabetik hastalarda ED’nin normal populasyona göre daha sık görüldüğünü desteklemektedir. Diyabete eşlik eden abdominal obezite, hiperlipidemi ve koroner arter hastalığı diyabetik erkeklerde ED için birer risk faktörüdür. ED’nun yaşam kalitesini çok büyük oranda etkilediği düşünüldüğünde tip 2 diyabeti olan erkeklerin özellikle de eşlik eden risk faktörleri varsa rutin tarama yapılması gerektiğini düşünmekteyiz.

 

 

References

  • NIH consensus development panel on impotence. JAMA 1993;270:83-90.
  • Sharifi F, Asghari M, Jaberi Y, et al. Independent Predictors of Erectile Dysfunction in Type 2 Diabetes Mellitus: Is It TrueWhat They Say about Risk Factors? ISRN Endocrinology 2012;2 (doi:10.5402/2012/502353).
  • İnal G. Erektil disfonksiyon ve diyabet. Androloji Bülteni 2005;20:1-3.
  • Yamasaki H, Ogawa K, Sasaki H, et al. Prevalence and risk factors of erectile dysfunction in Japanese men with type 2 diabetes. Diabetes Res Clin Pract 2004;66 (Suppl-1):173-7.
  • Kendirci M, Kadıoğlu A. Diyabet ve erektil disfonksiyon. Aktüel Tıp Diyabet Forumu 2002;7:34-43.
  • De Berardis G, Franciosi M, Belfiglio M, et al. Erectile dysfunction and quality of life in type 2 diabetic patients: A serious problem too often overlooked. Diabetes Care 2002;25:284-91.
  • Malavige LS, Levy JC. Erectile dysfunction in diabetes mellitus. J Sex Med 2009;6:1232-47.
  • Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrik I, Mishra A. The International Index of Erectile Function (IIEF). A multidimensional scale for assessment of erectile dysfunction. Urology 1997;49:822-36.
  • Kamenov ZA. A Comprehensive Review of Erectile Dysfunction in Men with Diabetes. Exp Clin Endocrinol Diabetes 2015;123:141-58.
  • Sasaki H, Yamasaki H, Ogawa K et al. Prevalance and risk factors of erectile dysfunction in Japanese diabetics. Diabetes Researh and Clinical Practice 2005;70:81-9.
  • Goyal A, Singh P, Ahuja A. Prevalence and Severity of Erectile Dysfunction as Assessed by IIEF-5 in North Indian Type 2 Diabetic Males and Its Correlation with Variables. J Clin Diagn Res 2013;7:2936-8.
  • Sargın M, Sargın H, Türkbörü Ü, Alp R. Prevalence and risk factors of erectile dysfunction in Type 2 diabetic men: A hospital based study. Endokrinolojide Yönelişler 2004;13:128-30.
  • Giugliano F, Maiorino M, Bellastella G, Gicchino M, Giugliano D, Espoksito K. Determinants of erectile dysfunction in type 2 diabetes. Int J Impot Res 2010;22:204-9. 14. Mutagaywa RK, Lutale J, Aboud M, Kamala associated factors among diabetic men attending diabetic clinic at Muhimbili National Hospital in Dar-es-Salaam, Tanzania. Pan Afr Med J 2014;26:227. BA.
  • Prevalence of erectile dysfunction and
  • Cander S, Coban S, Altuner S et al. Prevalence and correlates of erectile dysfunction in type 2 diabetes mellitus: a cross-sectional single-center study among Turkish patients. Metab Syndr Relat Disord 2014;12:324-9.
  • Kalter-Leibovici O, Wainstein J, Ziv A et al. Clinical, socioeconomic and lifestyle parameters associated with erectile dysfunction among diabetic men. Diabetes Care 2005;28:1739-44.
  • Ahmed I, Aamir Au, Anwar E, Ali SS, Ali A, Ali A. Erectile dysfunction and type 2 diabetes mellitus in northern Pakistan. J Pak Med Assoc 2013;63:1486-90.
  • Akkus E, Kadioglu A, Esen A et al. Prevalence and correlates of erectile dysfunction in Turkey: a population based study. Eur Urol 2002;41:298-304.
  • Al-Hunayan A, Al-Mutart, Kehinde E. et al. The prevalence and predictors of erectile dysfunction in men with newly diagnosed with Type 2 diabetes mellitus. BJU International 2007;99:130-4
  • Bal K, Oder M, Sahin AS et al. Prevalence of metabolic syndrome and its association with erectile dysfunction among urologic patients: metabolic backgrounds of erectile dysfunction. Urology 69:356-60.
  • Janiszewski PM, Janssen I, Ross R. Abdominal obesity and physical inactivity are associated with erectile dysfunction independent of body mass index. J Sex Med 2009;6:1990-8.
  • Harris MI, Klein R, Welborn TA, Knuiman MW. Onset of NIDDM occurs at least 4-7 yr before clinical diagnosis. Diabetes Care 1992;15:815-9.
There are 22 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Buket Tekin Vatansever

Sakin Tekin This is me

Tülay Karabayraktar

Berfu Çınkıt This is me

Şule Temizkan This is me

Ekrem Orbay This is me

Mehmet Sargın

Publication Date May 2, 2015
Published in Issue Year 2015 Volume: 15 Issue: 2

Cite

APA Tekin Vatansever, B., Tekin, S., Karabayraktar, T., Çınkıt, B., et al. (2015). Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi. Ankara Medical Journal, 15(2). https://doi.org/10.17098/amj.66012
AMA Tekin Vatansever B, Tekin S, Karabayraktar T, Çınkıt B, Temizkan Ş, Orbay E, Sargın M. Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi. Ankara Med J. May 2015;15(2). doi:10.17098/amj.66012
Chicago Tekin Vatansever, Buket, Sakin Tekin, Tülay Karabayraktar, Berfu Çınkıt, Şule Temizkan, Ekrem Orbay, and Mehmet Sargın. “Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi”. Ankara Medical Journal 15, no. 2 (May 2015). https://doi.org/10.17098/amj.66012.
EndNote Tekin Vatansever B, Tekin S, Karabayraktar T, Çınkıt B, Temizkan Ş, Orbay E, Sargın M (May 1, 2015) Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi. Ankara Medical Journal 15 2
IEEE B. Tekin Vatansever, S. Tekin, T. Karabayraktar, B. Çınkıt, Ş. Temizkan, E. Orbay, and M. Sargın, “Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi”, Ankara Med J, vol. 15, no. 2, 2015, doi: 10.17098/amj.66012.
ISNAD Tekin Vatansever, Buket et al. “Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi”. Ankara Medical Journal 15/2 (May 2015). https://doi.org/10.17098/amj.66012.
JAMA Tekin Vatansever B, Tekin S, Karabayraktar T, Çınkıt B, Temizkan Ş, Orbay E, Sargın M. Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi. Ankara Med J. 2015;15. doi:10.17098/amj.66012.
MLA Tekin Vatansever, Buket et al. “Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi”. Ankara Medical Journal, vol. 15, no. 2, 2015, doi:10.17098/amj.66012.
Vancouver Tekin Vatansever B, Tekin S, Karabayraktar T, Çınkıt B, Temizkan Ş, Orbay E, Sargın M. Diyabetik Erkeklerde Erektil Disfonksiyon Risk Faktörlerinin Değerlendirilmesi. Ankara Med J. 2015;15(2).