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Kemik İliği Nakli Hastalarında Nutrisyonel Risk Saptanması ve Etkileyen Faktörler

Year 2022, , 21 - 30, 31.01.2022
https://doi.org/10.46237/amusbfd.939853

Abstract

Amaç: Bu çalışma geçmiş yıllardaki hasta verilerimiz doğrultusunda elde edilen sonuçlarla, gelecekte nakil yapılacak hastalar için beslenme desteğinde yeni yöntemler geliştirebilmek amacıyla retrospektif olarak planlandı.
Yöntem: Retrospektif olarak planlanan çalışmada Ocak 2015 ile Haziran 2017 tarihleri arasında özel bir hastanenin erişkin kemik iliği nakli ünitesinde tedavisi yapılmış hematolojik maligniteli 118 kayıtlı hasta dosyasının 116 tanesi çalışmaya alındı, 2 hasta dosyası veri eksikliği nedeniyle çalışmadan çıkarıldı. Hasta verilerini toplarken hemşire gözlem notları ve hekim notları değerlendirildi. Veriler kişisel özellikler formu ve klinik parametreler formuna kaydedildi. Veriler doğrultusunda Nutrisyonel Risk Taraması formu doldurularak risk puanları hesaplandı. Anlamlılık p<0.05 düzeyinde değerlendirildi.
Bulgular: Yabancı uyruklu hastalarda (t=4,08, p<0,0001), lösemi tanısı ile tedavi görenlerde (F=7,25, p=0,001), alojenik kemik iliği nakli olanlarda (t=3,66, p<0,0001), bulantı-kusma olanlarda (t=3,00, p=0,003), oral alımı kısıtlananlarda (t=2,91, p=0,004), nutrisyonel desteğe ihtiyacı olanlarda (t=-3,64, p=0,005), mukozite bağlı ağrısı olanlarda (t=-3,87, p<0,0001) nutrisyonel risk tarama puanının daha yüksek olduğu saptandı.
Sonuç: Hastaların büyük çoğunluğunda kilo kaybı geliştiği, nutrisyonel risk tarama puanının yabancı uyruklu hastalarda, bulantı kusması olanlarda ve allojenik nakillerde daha yüksek olduğu belirlendi. Bu veriler doğrultusunda özellikle bu hasta gruplarında beslenme alışkanlıklarının önceden değerlendirilmesi, hastaların sosyo-kültürel durumlarına uygun yemek seçimlerinin sağlanması ve hemşirelerin beslenmeyle ilgili kararlarda aktif rol alması önerilebilir.

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References

  • 1. Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., et al. (2017). ESPEN guidelines on nutrition in cancer patients. Clinical nutrition (Edinburgh, Scotland), 36(1), 11–48. https://doi.org/10.1016/j.clnu.2016.07.015
  • 2. Baumgartner, A., Bargetzi, M., Bargetzi, A., Zueger, N., Medinger, M., Passweg, J., et al. (2017). Nutritional support practices in hematopoietic stem cell transplantation centers: A nationwide comparison. Nutrition (Burbank, Los Angeles County, Calif.), 35, 43–50. https://doi.org/10.1016/j.nut.2016.10.007
  • 3. Fuji, S., Einsele, H., Savani, B. N., & Kapp, M. (2015). Systematic Nutritional Support in Allogeneic Hematopoietic Stem Cell Transplant Recipients. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(10), 1707–1713. )
  • 4. Rieger, C. T., Wischumerski, I., Rust, C., & Fiegl, M. (2015). Weight Loss and Decrease of Body Mass Index during Allogeneic Stem Cell Transplantation Are Common Events with Limited Clinical Impact. PloS one, 10(12), e0145445. https://doi.org/10.1371/journal.pone.0145445
  • 5. Jaime-Pérez, J. C., Colunga-Pedraza, P. R., Gutiérrez-Gurrola, B., Brito-Ramírez, A. S., Gutiérrez-Aguirre, H., Cantú-Rodríguez, O. G., et al. (2013). Obesity is associated with higher overall survival in patients undergoing an outpatient reduced-intensity conditioning hematopoietic stem cell transplant. Blood Cells, Molecules, and Diseases, 51(1), 61-65.
  • 6. Muhsiroğlu, Ö. (2018). Hematopoietik kök kücre nakli yapılan hastalarda beslenme durumunun değerlendirilmesi ve deslenmenin nakil ile ilişkili parametrelere etkisinin incelenmesi (Doktora Tezi). Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü, ANKARA.
  • 7. Doney, K., McMillen, K., Buono, L., Deeg, H. J., & Gooley, T. (2019). Impact of Body Mass Index on Outcomes of Hematopoietic Stem Cell Transplantation in Adults. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 25(3), 613–620. https://doi.org/10.1016/j.bbmt.2018.10.006
  • 8. Farhadfar, N., Kelly, D. L., Mead, L., Nair, S., Colee, J., Irizarry Gatell,et al.(2020). Dietary Intake and Diet Quality of Hematopoietic Stem Cell Transplantation Survivors. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26(6), 1154–1159. https://doi.org/10.1016/j.bbmt.2020.02.017
  • 9. Lazarow, H., Nicolo, M., Compher, C., Kucharczuk, C. R., Stadtmauer, E. A., & Landsburg, D. J. (2019). Nutrition-Related Outcomes for Autologous Stem Cell Transplantation Patients. Clinical lymphoma, myeloma & leukemia, 19(7), e393–e398. https://doi.org/10.1016/j.clml.2019.04.002
  • 10. Garzón Herazo, J. R., Mauricio Muñoz Velandia, O., Solano, J. C., Molina Pimienta, L., & Figueroa Lemus, W. J. (2020). The nutrition risk index is associated with bacteraemia within 30 days after autologous stem cell transplantation in patients with multiple myeloma. Transplant Infectious Disease, e13302.
  • 11. Ferreira, E. E., Guerra, D. C., Baluz, K., de Resende Furtado, W., & da Silva Bouzas, L. F. (2014). Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study. Revista brasileira de hematologia e hemoterapia, 36(6), 414–419. https://doi.org/10.1016/j.bjhh.2014.07.014
  • 12. Skaarud, K. J., Hjermstad, M. J., Bye, A., Veierød, M. B., Gudmundstuen, A. M., Lundin, K. E., et al. (2018). Effects of individualized nutrition after allogeneic hematopoietic stem cell transplantation following myeloablative conditioning; a randomized controlled trial. Clinical nutrition ESPEN, 28, 59-66.
  • 13. Akbulut, G. (2013). Medical nutritional therapy in hematopoietic stem cell transplantation (HSCT). International Journal of Hematology and Oncology, 29(4), 055-065.
  • 14. Kamiya, T., Hira, D., Hoshino, N., Kurihara, M., Nakagawa, M., Sasaki, M., et al. (2019). Low Body Mass Index and Myeloablative Conditioning Regimen Prolong the Duration of Parenteral Nutrition During Hematopoietic Stem Cell Transplantation. Annals of Nutrition and Metabolism, 74(2), 107-114.
  • 15. Bolayır, B. (2014). Hospitalize hastalarda nutrisyonel değerlendirme testi NRS2002'nin (Nutritional Risk Screening-2002) geçerlilik ve güvenilirliğinin değerlendirilmesi. (Yayımlanmamış Uzmanlık Tezi). Hacettepe Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, ANKARA.
  • 16. Beşirli, H. (2010). Yemek, kültür ve kimlik. Milli Folklor, 22(87), 159-169.
  • 17. Güler, S. (2010). Türk mutfak kültürü ve yeme içme alışkanlıkları. Dumlupınar Üniversitesi Sosyal Bilimler Dergisi, 26(S 1), 24-30.
  • 18. Rzepecki, P., Barzal, J., Sarosiek, T., Oborska, S., & Szczylik, C. (2007). Nutritional assessment during allogeneic hematopoietic stem cell transplantation: single centre experience. Journal-Balkan Union Of Oncology, 12(2), 253.
  • 19. Bechard, L. J., Guinan, E. C., Feldman, H. A., Tang, V., & Duggan, C. (2007). Prognostic factors in the resumption of oral dietary intake after allogeneic hematopoietic stem cell transplantation (HSCT) in children. JPEN. Journal of parenteral and enteral nutrition, 31(4), 295–301. https://doi.org/10.1177/0148607107031004295
  • 20. Lipkin, A. C., Lenssen, P., & Dickson, B. J. (2005). Nutrition issues in hematopoietic stem cell transplantation: state of the art. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 20(4), 423–439. https://doi.org/10.1177/0115426505020004423
  • 21. Guièze, R., Lemal, R., Cabrespine, A., Hermet, E., Tournilhac, O., Combal, C., et al. (2014). Enteral versus parenteral nutritional support in allogeneic haematopoietic stem-cell transplantation. Clinical nutrition (Edinburgh, Scotland), 33(3), 533–538. https://doi.org/10.1016/j.clnu.2013.07.012
  • 22. Fang, Y., Liu, M. J., Zhang, W. W., Xie, C., & Liu, Z. Z. (2020). Nutrition Support Practices of Hematopoietic Stem Cell Transplantation Centers in Mainland China. Current Medical Science, 40(4), 691- 698.

Determination of Nutritional Risk in Bone Marrow Transplantation Patients and Influencing Factors

Year 2022, , 21 - 30, 31.01.2022
https://doi.org/10.46237/amusbfd.939853

Abstract

Objective: The aim of this study was to analyse the data of transplant patients retrospectively in order to develop new methods of nutritional support for the future.
Methods: Files of 116 bone marrow translant patients who were treated at private Hospital between January 2015 and June 2017 were analysed. Demographic characteristics, clinical parameters, nurse observation notes, physician notes were examined.
Results: It was found that the nutritional risk screening score was higher in patients who needed nutritional support, with pain due to mucositis , in foreign nationals , had nausea / vomiting , in allogeneic transplants, had oral intake is restricted.
Conclusion: There was a significant difference between the nutritional risk screening score and age groups, in patients with foreign nationality, nausea /vomiting, and allogeneic transplants. In this group of patients, it may be advisable to evaluate the nutritional habits in advance, to provide appropriate food choices according to the socio-cultural status of the patients and to take an active role in nutrition decisions.

Project Number

Yok

References

  • 1. Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., et al. (2017). ESPEN guidelines on nutrition in cancer patients. Clinical nutrition (Edinburgh, Scotland), 36(1), 11–48. https://doi.org/10.1016/j.clnu.2016.07.015
  • 2. Baumgartner, A., Bargetzi, M., Bargetzi, A., Zueger, N., Medinger, M., Passweg, J., et al. (2017). Nutritional support practices in hematopoietic stem cell transplantation centers: A nationwide comparison. Nutrition (Burbank, Los Angeles County, Calif.), 35, 43–50. https://doi.org/10.1016/j.nut.2016.10.007
  • 3. Fuji, S., Einsele, H., Savani, B. N., & Kapp, M. (2015). Systematic Nutritional Support in Allogeneic Hematopoietic Stem Cell Transplant Recipients. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(10), 1707–1713. )
  • 4. Rieger, C. T., Wischumerski, I., Rust, C., & Fiegl, M. (2015). Weight Loss and Decrease of Body Mass Index during Allogeneic Stem Cell Transplantation Are Common Events with Limited Clinical Impact. PloS one, 10(12), e0145445. https://doi.org/10.1371/journal.pone.0145445
  • 5. Jaime-Pérez, J. C., Colunga-Pedraza, P. R., Gutiérrez-Gurrola, B., Brito-Ramírez, A. S., Gutiérrez-Aguirre, H., Cantú-Rodríguez, O. G., et al. (2013). Obesity is associated with higher overall survival in patients undergoing an outpatient reduced-intensity conditioning hematopoietic stem cell transplant. Blood Cells, Molecules, and Diseases, 51(1), 61-65.
  • 6. Muhsiroğlu, Ö. (2018). Hematopoietik kök kücre nakli yapılan hastalarda beslenme durumunun değerlendirilmesi ve deslenmenin nakil ile ilişkili parametrelere etkisinin incelenmesi (Doktora Tezi). Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü, ANKARA.
  • 7. Doney, K., McMillen, K., Buono, L., Deeg, H. J., & Gooley, T. (2019). Impact of Body Mass Index on Outcomes of Hematopoietic Stem Cell Transplantation in Adults. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 25(3), 613–620. https://doi.org/10.1016/j.bbmt.2018.10.006
  • 8. Farhadfar, N., Kelly, D. L., Mead, L., Nair, S., Colee, J., Irizarry Gatell,et al.(2020). Dietary Intake and Diet Quality of Hematopoietic Stem Cell Transplantation Survivors. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26(6), 1154–1159. https://doi.org/10.1016/j.bbmt.2020.02.017
  • 9. Lazarow, H., Nicolo, M., Compher, C., Kucharczuk, C. R., Stadtmauer, E. A., & Landsburg, D. J. (2019). Nutrition-Related Outcomes for Autologous Stem Cell Transplantation Patients. Clinical lymphoma, myeloma & leukemia, 19(7), e393–e398. https://doi.org/10.1016/j.clml.2019.04.002
  • 10. Garzón Herazo, J. R., Mauricio Muñoz Velandia, O., Solano, J. C., Molina Pimienta, L., & Figueroa Lemus, W. J. (2020). The nutrition risk index is associated with bacteraemia within 30 days after autologous stem cell transplantation in patients with multiple myeloma. Transplant Infectious Disease, e13302.
  • 11. Ferreira, E. E., Guerra, D. C., Baluz, K., de Resende Furtado, W., & da Silva Bouzas, L. F. (2014). Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study. Revista brasileira de hematologia e hemoterapia, 36(6), 414–419. https://doi.org/10.1016/j.bjhh.2014.07.014
  • 12. Skaarud, K. J., Hjermstad, M. J., Bye, A., Veierød, M. B., Gudmundstuen, A. M., Lundin, K. E., et al. (2018). Effects of individualized nutrition after allogeneic hematopoietic stem cell transplantation following myeloablative conditioning; a randomized controlled trial. Clinical nutrition ESPEN, 28, 59-66.
  • 13. Akbulut, G. (2013). Medical nutritional therapy in hematopoietic stem cell transplantation (HSCT). International Journal of Hematology and Oncology, 29(4), 055-065.
  • 14. Kamiya, T., Hira, D., Hoshino, N., Kurihara, M., Nakagawa, M., Sasaki, M., et al. (2019). Low Body Mass Index and Myeloablative Conditioning Regimen Prolong the Duration of Parenteral Nutrition During Hematopoietic Stem Cell Transplantation. Annals of Nutrition and Metabolism, 74(2), 107-114.
  • 15. Bolayır, B. (2014). Hospitalize hastalarda nutrisyonel değerlendirme testi NRS2002'nin (Nutritional Risk Screening-2002) geçerlilik ve güvenilirliğinin değerlendirilmesi. (Yayımlanmamış Uzmanlık Tezi). Hacettepe Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, ANKARA.
  • 16. Beşirli, H. (2010). Yemek, kültür ve kimlik. Milli Folklor, 22(87), 159-169.
  • 17. Güler, S. (2010). Türk mutfak kültürü ve yeme içme alışkanlıkları. Dumlupınar Üniversitesi Sosyal Bilimler Dergisi, 26(S 1), 24-30.
  • 18. Rzepecki, P., Barzal, J., Sarosiek, T., Oborska, S., & Szczylik, C. (2007). Nutritional assessment during allogeneic hematopoietic stem cell transplantation: single centre experience. Journal-Balkan Union Of Oncology, 12(2), 253.
  • 19. Bechard, L. J., Guinan, E. C., Feldman, H. A., Tang, V., & Duggan, C. (2007). Prognostic factors in the resumption of oral dietary intake after allogeneic hematopoietic stem cell transplantation (HSCT) in children. JPEN. Journal of parenteral and enteral nutrition, 31(4), 295–301. https://doi.org/10.1177/0148607107031004295
  • 20. Lipkin, A. C., Lenssen, P., & Dickson, B. J. (2005). Nutrition issues in hematopoietic stem cell transplantation: state of the art. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 20(4), 423–439. https://doi.org/10.1177/0115426505020004423
  • 21. Guièze, R., Lemal, R., Cabrespine, A., Hermet, E., Tournilhac, O., Combal, C., et al. (2014). Enteral versus parenteral nutritional support in allogeneic haematopoietic stem-cell transplantation. Clinical nutrition (Edinburgh, Scotland), 33(3), 533–538. https://doi.org/10.1016/j.clnu.2013.07.012
  • 22. Fang, Y., Liu, M. J., Zhang, W. W., Xie, C., & Liu, Z. Z. (2020). Nutrition Support Practices of Hematopoietic Stem Cell Transplantation Centers in Mainland China. Current Medical Science, 40(4), 691- 698.
There are 22 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Research Articles
Authors

Seckin Erdal 0000-0002-9279-9686

Elif Şimşek This is me 0000-0001-8265-9527

Efnan Keflioğlu This is me 0000-0001-6930-6655

Buket Öztürk This is me 0000-0003-2509-4851

Gülçin Başol This is me 0000-0002-5626-3534

Nupel Çolak This is me 0000-0002-5061-3214

Gülbeyaz Can 0000-0002-5368-0893

Project Number Yok
Publication Date January 31, 2022
Published in Issue Year 2022

Cite

APA Erdal, S., Şimşek, E., Keflioğlu, E., Öztürk, B., et al. (2022). Kemik İliği Nakli Hastalarında Nutrisyonel Risk Saptanması ve Etkileyen Faktörler. Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 6(1), 21-30. https://doi.org/10.46237/amusbfd.939853