The Effect of Weight Loss by Acupuncture Therapy on Fecal Microbiota Composition in Obese Female Patients

Year 2025, Volume: 9 Issue: 1, 12 - 22, 31.01.2025

Tuba Batur , Fatma Hümryra Yerlikaya , Hayriye Baltaoğlu Alp , Mehmet Aköz

https://doi.org/10.46237/amusbfd.1414224

Abstract

Objective: The aim of this study was to investigate the possible effects of acupuncture therapy on anthropometric and biochemical parameters, as well as on gut microbiota in obese females and to describe any changes that occurred.
Method: This prospectively designed study was approved by the xxx Faculty of Medicine Ethics Committee for Research on Medicine and Non-Medical Devices, dated 11.04.2019 and numbered 2019/1820. This study was performed on voluntary obese female individuals who applied to xxx Center between May 2019 and December 2019 to lose weight. The study was conducted with 15 individuals who displayed the following inclusion criteria: aged 34–45, female gender, body mass index (BMI)≥30 kg/m2, not taking antibiotic medication in the last six months, no known systemic disease (diabetes mellitus, hypertension, chronic kidney disease, etc.), no smoking or alcohol use, not pregnant, not using supplements such as probiotics, antioxidants, vitamins, etc., and not using systemic drugs.
Results: The ages and anthropometric and biochemical measurements of a total of 15 individuals (acupuncture group, n=9; diet group, n=6) included in the study as a consequence of two different treatment methods are summarized in Table 1. There was no significant difference observed in pre-treatment (0 month) levels of age, body weight, BMI, waist circumference, glucose, insulin, and HOMA-IR of the groups (p>0.05).
Conclusion: Considering the detected results of relationship between PA level sleep quality and well-being in the present study, we suggest that regular and adequate PA in every period of life, especially such a sedentary life process may have positive impacts on the sleep quality, energy and well-being, and reduce conditions such as depression and anxiety for individuals with DM.

Keywords

Acupuncture, Losing weight, Microbiota, Obesity

Project Number

191518008

Obez Kadın Hastalarda Akupunktur Tedavisi ile Kilo Kaybının Gaita Mikrobiyota Kompozisyonu Üzerine Etkisi

Abstract

Amaç: Bu çalışmanın amacı, akupunktur tedavisinin antropometrik ve biyokimyasal parametreler ile obez kadınlarda bağırsak mikrobiyotası üzerindeki olası etkilerini araştırmak ve meydana gelen değişiklikleri tanımlamaktır.
Yöntem: Prospektif olarak tasarlanan bu çalışma, Necmettin Erbakan Üniversitesi Tıp Fakültesi İlaç ve Tıbbi Olmayan Cihaz Araştırmaları Etik Kurulu'nun 11.04.2019 tarih ve 2019/1820 numarasıyla onaylandı. Bu çalışma Mayıs 2019 ile Aralık 2019 tarihleri arasında Necmettin Erbakan Üniversitesi GETAT Merkezine kilo vermek amacıyla başvuran gönüllü obez kadın bireyler üzerinde gerçekleştirilmiştir. Çalışmaya 34-45 yaş aralığında, kadın cinsiyette, vücut kitle indeksi (BMI) ≥30 kg/m2, son altı ayda antibiyotik kullanmamış, bilinen sistemik hastalığı (diyabet) bulunmayan 15 kişi katılmıştır. Dışlanma kriterleri; Diyabet Mellitus, hipertansiyon, kronik böbrek hastalığı vb.) olması, sigara ve alkol kullanması, hamile olmak, probiyotik, antioksidan, vitamin vb. takviyeleri kullanması ve sistemik ilaç kullanması olarak belirlenmiştir. Toplam 15 kişi çalışmaya katılmıştır. Hastalar 2 gruba ayrılarak akupunktur ve diyet grubu oluşturulmuştur. Grupların demografik verileri ile antropometrik ve biyokimyasal ölçümleri aynı laboratuvar ve aynı hemşire tarafından yapıldı.
Bulgular: Çalışmaya dahil edilen toplam 15 kişinin (akupunktur grubu, n=9; diyet grubu, n=6) iki farklı tedavi yöntemi sonucu yaşları ile antropometrik ve biyokimyasal ölçümleri Tablo 1'de özetlenmiştir.
Sonuç: Grupların tedavi öncesi (0 ay) yaş, vücut ağırlığı, BMI, bel çevresi, glukoz, insülin ve HOMA-IR düzeylerinde farklılık gözlendi (p>0.05).

Keywords

Akupunktur, Kilo verme, Mikrobiyota, Obezite

Ethical Statement

2019/1820 sayılı karar ile Necmettin Erbakan üniversitesi Meram Tıp Etik kurulundan alınmıştır.

Supporting Institution

Necmettin Erbakan üniversitesi BAP Koordinatörlüğü

Project Number

191518008

Thanks

Necmettin Erbakan üniversitesi BAP Koordinatörlüğü

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