Determining the relationship between gastrointestinal symptoms and comfort in inflammatory bowel patients

Year 2024, , 139 - 146, 29.05.2024

Aylin Bilgin

https://doi.org/10.21673/anadoluklin.1322030

Abstract

Aim: This study aimed to reveal the effect of gastrointestinal symptoms on comfort levels in patients diagnosed with inflammatory bowel disease.

Methods: A cross-sectional study design was used. 115 patients diagnosed with inflammatory bowel disease between January 15, 2023, and May 15, 2023, were included in this study. Comfort level was evaluated using the General Comfort Scale Short Form. The data were analyzed using descriptive statistics, and regression analyses.

Results: The mean age in the study was The mean age in the study was 41.29 (standard deviation (SD)= 12.81) year. The mean comfort level was 98.93 (SD=19.06). There was a difference between gastrointestinal symptom burden scores according to gender (t = 3.048, p = 0.003), marital status There was a difference between gastrointestinal symptom burden scores according to gender (independent sample t-test (t) = 3.048, p = 0.003), and the presence of chronic disease (t = -4.115, p < 0.001). There is a weak negative relationship between age and comfort level There is a weak negative relationship between age and comfort level (pearson correlation (r) = -0.191, p = 0.041).

Conclusion: This study emphasized that gastrointestinal symptom burden is an important determinant of comfort level in patients diagnosed with inflammatory bowel disease and comfort decreases as gastrointestinal symptom load increases.

Keywords

Crohn disease, inflammatory bowel diseases, patient comfort, symptom assessment, ulcerative colitis

İnflamatuvar bağırsak hastalarında gastrointestinal semptomlar ile konfor arasındaki ilişkinin belirlenmesi

Abstract

Amaç: Bu çalışma, inflamatuar bağırsak hastalığı tanısı olan hastalarda gastrointestinal semptomların konfor düzeyine etkisini ortaya koymayı amaçladı.

Yöntemler: Kesitsel bir çalışma tasarımı kullanıldı. 15 Ocak 2023 ile 15 Mayıs 2023 tarihleri arasında inflamatuar bağırsak hastalığı tanısı almış 115 hasta bu çalışmaya dahil edildi. Konfor düzeyi, Genel Konfor Ölçeği Kısa Formu kullanılarak değerlendirildi. Veriler, tanımlayıcı istatistikler ve regresyon analizleri kullanılarak analiz edildi.

Bulgular: Çalışmada yaş ortalaması 41,29 (standart sapma (SD)= 12,81) idi. Ortalama konfor düzeyi 98.93 (SD=19.06) idi. Cinsiyet (bağımsız örneklem t testi (t)=3.048, p=0.003), medeni durum (t=-2.156, p=0.033) ve kronik hastalık varlığına (t=-4.115, p<0.001) göre gastrointestinal semptom yükü puanları arasında fark saptandı. Yaş ile konfor düzeyi arasında zayıf bir negatif ilişki bulundu Yaş ile konfor düzeyi arasında zayıf bir negatif ilişki bulundu (pearson korelasyon (r) = -0,191, p = 0,041).

Sonuç: Bu çalışmada inflamatuar bağırsak hastalığı tanısı olan hastalarda gastrointestinal semptom yükünün konfor düzeyinin önemli bir belirleyicisi olduğu ve gastrointestinal semptom yükü arttıkça konforun azaldığı vurgulanmıştır.

Keywords

Crohn hastalığı, hasta konforu, inflamatuar bağırsak hastalıkları, semptom değerlendirmesi, ülseratif kolit

References

• Singh AK, Jena A, Kumar‐M P, Sharma V, Sebastian S. Risk and outcomes of coronavirus disease in patients with inflammatory bowel disease: a systematic review and meta‐analysis. United European Gastroenterol J. 2021;9(2):159-76.
• Seyedian SS, Nokhostin F, Malamir MD. A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease. J Med Life. 2019;12(2):113-22.
• Chang JT. Pathophysiology of inflammatory bowel diseases. N Engl J Med Overseas Ed. 2020;383(27):2652-64.
• Kaplan GG, Windsor JW. The four epidemiological stages in the global evolution of inflammatory bowel disease. Nat Rev Gastroenterol Hepatol. 2021;18(1):56-66.
• Çakir ÖÖ. The incidence and the demographic and clinical characteristics of patients with inflammatory bowel disease in our region. The Turkish Journal of Academic Gastroenterology. 2019;18(2):49-58.
• Uran BÖ. Symptom management of inflammatory bowel diseases with current guideline suggestions. Journal of Uludağ University Medical Faculty. 2020;46(1):101-11.
• Öztürk N, Yıldırım Y. Drug compliance and quality of life in patients with inflammatory bowel disease. Bandırma Onyedi Eylül University Journal of Health Sciences and Research.2020;2(3):192-9.
• Perler BK, Ungaro R, Baird G, et al. Presenting symptoms in inflammatory bowel disease: descriptive analysis of a community-based inception cohort. BMC Gastroenterol. 2019;19:1-8.
• Barberio B, Zamani M, Black CJ, Savarino EV, Ford AC. Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2021;6(5):359-70.
• Jones JL, Nguyen GC, Benchimol EI, et al. The impact of inflammatory bowel disease in Canada 2018: quality of life. J Can Assoc Gastroenterol. 2019;2(Supplement_1):42-8.
• Melo GAA, Aguiar LL, Silva RA, Quirino GdS, Pinheiro AKB, Caetano JÁ. Factors related to impaired comfort in chronic kidney disease patients on hemodialysis. Rev Bras Enferm. 2019;72:889-95.
• Kolcaba K, Tilton C, Drouin C. Comfort theory: a unifying framework to enhance the practice environment. J Nurs Adm. 2006;36(11):538-44.
• Boudiab LD, Kolcaba K. Comfort theory. ANS Adv Nurs Sci. 2015;38(4):270-8.
• Krinsky R, Murillo I, Johnson J. A practical application of Katharine Kolcaba’s comfort theory to cardiac patients. Appl Nurs Res. 2014;27(2):147-50.
• Şenturk SG. The importance of self-management strategies and the role of nurses in the management of chronic diseases. Eurasian JHS. 2021;4(1):9-13.
• Terzi B, Kaya N. Comfort Theory and Analysis. Journal of Anatolia Nursing and Health Sciences. 2017;20(1):67-74.
• Kılıç S. Sampling methods. Journal of Mood Disorders. 2013;3(1):44-6.
• Iordache MM, Tocia C, Aschie M, et al. Intestinal permeability and depression in patients with inflammatory bowel disease. J Clin Med. 2022;11(17):5121.
• Yanartaş Ö, Biçakci E, Şenkal Z, et al. Assessment of psychiatric symptoms and quality of life in patients with inflammatory bowel disease. Journal of Mood Disorders. 2014;4(3):115-21.
• Parlak E, Dagli U, Alkim C, et al. Pattern of gastrointestinal and psychosomatic symptoms across the menstrual cycle in women with inflammatory bowel disease. Turk J Gastroenterol. 2003;14(4):250-6.
• Revicki DA, Wood M, Wiklund I, Crawley J. Reliability and validity of the Gastrointestinal Symptom Rating Scale in patients with gastroesophageal reflux disease. Qual Life Res. 1997;7:75-83.
• Turan N, Asti TA, Kaya N. Reliability and validity of the Turkish version of the Gastrointestinal Symptom Rating Scale. Gastroenterol Nurs. 2017;40(1):47-55.
• Sarıtaş Çıtlık S, Çevik S, Gürkan Ö. Turkish validity and reliability study of the general comfort scale-short form. Nursing Form Diabetes, Obesity and Hypertension (Special Issue). 2018;10:16-23.
• Mishra P, Pandey CM, Singh U, Gupta A, Sahu C, Keshri A. Descriptive statistics and normality tests for statistical data. Ann Card Anaesth. 2019;22(1):67.
• Tabachnick BG, Fidell LS, Ullman JB. Using multivariate statistics (Vol. 5). Boston, MA: pearson; 2007.
• Lee AD, Spiegel BM, Hays RD, et al. Gastrointestinal symptom severity in irritable bowel syndrome, inflammatory bowel disease and the general population. Neurogastroenterol Motil. 2017;29(5):e13003.
• Jerndal P, Ringström G, Agerforz P, et al. Gastrointestinal‐specific anxiety: an important factor for severity of GI symptoms and quality of life in IBS. Neurogastroenterol Motil. 2010;22(6):646-e179.
• Nilsson D, Ohlsson B. Gastrointestinal symptoms and irritable bowel syndrome are associated with female sex and smoking in the general population and with unemployment in men. Front Med. 2021;8:646658.
• Almario CV, Ballal ML, Chey WD, Nordstrom C, Khanna D, Spiegel BM. Burden of gastrointestinal symptoms in the United States: results of a nationally representative survey of over 71,000 Americans. Am J Gastroenterol. 2018;113(11):1701.
• Aydın Özkan S, Kayan Şenol D, Aslan E. Comfort Level And Effectıve Factors In Thırd Trımester Pregnancy. E-Journal of Dokuz Eylul University Nursing Faculty. 2020;13(2):92-9.
• Demir B, Bulbuloglu S. The effect of immunosuppression therapy on activities of daily living and comfort level after liver transplantation. Transpl Immunol. 2021;69:101468.
• Boudiab LD, Kolcaba K. Comfort theory. ANS Adv Nurs Sci. 2015;38(4):270-278.
• Nuccio T, Nuccio P. Give them comfort: Controlling COPD symptoms at the end of life. The Journal for Resp Care Pract. 2009;86(6):30-33.