Otizm Spektrum Bozuklukları Olan Bir Türk Popülasyonda Erkek Genital Anomalileri Bulguları

Year 2019, , 72 - 77, 13.06.2019

Şahin Bodur , Hesna Gül , Miray Çetinkaya , Candan Taşkıran Yetiş Işıldar

https://doi.org/10.21673/anadoluklin.460738

Cited By: 1

Abstract

 Amaç: Otizm spektrum bozukluğu (OSB) heterojen bir
nörogelişimsel bozukluktur. Etiyo­lojisinde genetik ve erken dönemde maruz
kalınan çevresel faktörler önemli bir rol oynar. Bu faktörler, ayrıca OSB’li
çocuklarda konjenital anomalilerin prevalansını da etkiler. Bu ça­lışmada Türk
toplumunda OSB’li erkek hastalarda genital anomali prevalansını saptamak
amaçlanmıştır.

Gereç ve Yöntemler: OSB’li 11–316
aylık 524 çocuğun verileri geriye dönük olarak incelendi. OSB tanısı, genel
olarak ölçüm araçları ile değil, klinik muayeneler ile konmuştu.

Bulgular: Hastaların 432’si
(%82,4) erkek, 92’si (%17,6) kızdı. 432 (%4,4) erkek hastanın 19’u herhangi bir
genital anomaliye sahipti. Bu 19 hastanın 10’una (%52) kriptorşidizm (çalışma­mızda
görülen en yaygın genital anomali) tanısı konduğu saptandı.

Tartışma ve Sonuç: Bazı
limitasyonları olmakla birlikte, bu çalışma Türk toplumunda OSB’li erkek çocuklarda
genital anomali komorbiditesini araştıran büyük örneklemli az sayıdaki çalışmadan
biridir ve incelenen grupta erkek genital anomali insidansının yüksek olduğunu
göstermiştir.

Keywords

erkek genital anomalileri;, ; hipospadias, kriptorşidizm, OSB

Findings of male genital anomalies in a Turkish population with Autism Spectrum Disorders.

Abstract

Aims: Autism spectrum disorder
(ASD) is a set of heterogeneous neurodevelopmental con­ditions, and genetics
has a key role in the etiology, in connection with developmentally early
environmental factors. These factors also affect the prevalence of congenital
anomalies in children with ASD. This study aimed to determine the prevalence of
genital anomalies in male patients with ASD in the Turkish population.

Materials and Methods: Data of
524 children with ASD aged between 11 and 316 months were examined
retrospectively. The diagnosis was mostly established by clinical expression
and examination, rather than assessment using the formal tools.

Results: Four hundred and
thirty-two (82.4%) of the children were male and 92 (%17.6) were female. Only
19 of the 432 (4.4%) boys were diagnosed with a genital anomaly. Ten of the 19
patients (52%) was diagnosed with cryptorchidism, which was the most common
genital anomaly in our study.

Discussion and Conclusion: Despite having some limitations, this study is
one of the few studies with a large population that investigate the comorbidity
of genital anomalies in boys with ASD in the Turkish population, and showed
that male genital anomalies had a high incidence in the sample included.

Keywords

ASD, Male Genital anomalies, Cryptorchidism, hypospadia

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