İdiyopatik Santral Erken Ergenlik Tanılı Bir Grup Hastanın Başvuru ve Büyüme Özellikleri

Year 2021, , 277 - 281, 27.09.2021

Şeyma Sönmez Şahin , Ayla Güven

https://doi.org/10.21673/anadoluklin.815696

Abstract

Amaç: Bu çalışmada idiyopatik santral erken ergenlik (SEE) tanılı hastalarda etiyoloji, prognoz, klinik özellikler ve tedavi yanıtı üzerine bir değerlendirme amaçlanmıştır.
Yöntem: Çocuk endokrinoloji polikliniğimizde Haziran 2001—Eylül 2015 döneminde idiyopatik SEE tanısı konmuş olan toplam 175 hastanın tıbbi kayıtları geriye dönük olarak incelenmiştir.
Bulgular: Hastaların büyük kısmı kız ve 6 yaşından büyük idi. Gonadotropin salgılatıcı hormon analogları ile tedavinin kilo aldırmadığı, erken başvuru ve erken tedavi ile öngörülen boyda artış sağlandığı saptandı.
Sonuç: İdiyopatik SEE’li hastalarda erken tanı ve tedavi büyüme potansiyelinin korunmasında önemli bir rol oynamaktadır.

Keywords

erken ergenlik, erken ergenlik tedavisi, gonadotropin salgılatıcı hormon analogları, hedef boy, öngörülen boy

The Admission and Growth Characteristics of a Group of Patients Diagnosed with Idiopathic Central Precocious Puberty

Abstract

Aim: In this study, we aimed to evaluate the etiology, prognosis, clinical characteristics, and treatment response in patients diagnosed with idiopathic central precocious puberty (CPP).
Methods: We retrospectively reviewed the medical records of a total of 175 patients who were diagnosed with idiopathic CPP at our pediatric endocrinology outpatient clinic between June 2001 and September 2015.
Results: Most of the patients were girls and older than 6 years of age. We found that treatment with gonadotropin-releasing hormone analogues did not cause weight gain, and that younger age at admission and early treatment resulted in an increase in predicted height.
Conclusion: Early diagnosis and treatment play an important role in the preservation of growth potential in patients with idiopathic CPP.

Keywords

gonadotropin-releasing hormone analogues, precocious puberty, precocious puberty treatment, predicted height, target height

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