Case Report
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Erkek bir ergende metilfenidat ile indüklenen hiperhidrozis

Year 2017, Volume: 22 Issue: 1, 50 - 53, 30.12.2016
https://doi.org/10.21673/anadoluklin.252082

Abstract

Hiperhidrozis (aşırı terleme) dikkat eksikliği ve hiperaktivite bozukluğu nedeniyle metilfenidat tedavisi alna çocuklarda nadiren bildirilmiş bir ilaç yan etkisidir. Dikkat eksikliği ve hiperaktivite bozukluğu tanılı çocuk ve ergenlerde aşırı doz metilfenidat alımına bağlı hiperhidrozis bildirilen birkaç vaka örneği vardır.Biz bu olgu sunumumuzda dikkat eksikliği ve hiperaktivite bozukluğu tedavisi için uzun etkili metilfenidat ( Concerta ) kullanımı sonrası gelişen hiperhidrozis yan etkisini bildirdik.

References

  • Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al.,A method for estimating the probability of adverse drug reactions.,:239–45.,1981,30
  • Cheshire WP, Fealey RD. Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management. Drug Saf. 2008;31(2):109–26
  • . Coskun M, Kaya I. Painful muscle cramps possibly associated with withdrawal from methylphenidate. J Child Adolesc Psychopharmacol. 2016;26(7):658–9.
  • Coskun M, Adak I, Akaltun I. Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine. J Clin Psychopharmacol. 2014;34(4):537–8.
  • Coskun M. Methylphenidate induced obsessive-compulsive symptoms treated with sertraline. Bull Clin Psychopharmacol. 2011;21(3):275–6.
  • Kaya I, Coskun M. Diffuse maculopapular rash with increasing dosage of methylphenidate. J Clin Psychopharmacol. 2016;36(1):106–7.
  • Coskun M, Tutkunkardas MD, Zoroglu S. OROS methylphenidate-induced skin eruptions. J Child Adolesc Psychopharmacol. 2009;19(5):593–4.
  • Coskun M, Zoroglu S. A report of two cases of sexual side effects with OROS methylphenidate. J Child Adolesc Psychopharmacol. 2009;19(4):477–9.
  • Coskun M, Zoroglu S. Tactile and visual hallucinations in a child with methylphenidate and fluoxetine combination. J Clin Psychopharmacol. 2008;28(6):723–5.
  • Green WH. Sympathomimetic amines and central nervous system stimulants. Child and Adolescent Clinical Psychopharmacology, 4. ed. Philadelphia: Lippincott Williams & Wilkins; 2007:55–90.
  • Patel V, Krishna AS, Lefevre C, Kaagaza M, Wittkamp M. Methylphenidate Overdose causing secondary polydipsia and severe hyponatremia in an 8-year-old boy. Pediatr Emerg Care. DOI: 10.1097/PEC.0000000000000788
  • Hassanian-Moghaddam H, Ranjbar M, Farnaghi F, Zamani N, Alizadeh AM, Sarjami S. Stimulant Toxicity in Children: A Retrospective Study on 147 Patients. Pediatr Crit Care Med. 2015;16(8):290–6.
  • Khajehpiri Z, Mahmoudi-Gharaei J, Faghihi T, Karimzadeh I, Khalili H, Mohammadi M. Adverse reactions of methylphenidate in children with attention deficit-hyperactivity disorder: report from a referral center. J Res Pharm Pract. 2014;3(4):130–6
  • . The US Food and Drug Administration [Internet]. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021121s015s017l.pdf [accessed 22 July 2016].

Methylphenidate Induced Hyperhidrosis in an Adolescent Boy

Year 2017, Volume: 22 Issue: 1, 50 - 53, 30.12.2016
https://doi.org/10.21673/anadoluklin.252082

Abstract

Hyperhidrosis (excessive sweating) is a rarely
reported side effect of methylphenidate treatment in young subjects with attention-deficit/
hyperactivity disorder. There are few reports of hyperhidrosis
associated with methylphenidate overdose in children and adolescents with
diagnosis of . Here we report a case of an adolescent boy who
developed hyperhidrosis after taking osmotic-controlled release oral delivery
system  methylphenidate (Concerta) 
for his 
attention-deficit/ hyperactivity disorder

References

  • Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al.,A method for estimating the probability of adverse drug reactions.,:239–45.,1981,30
  • Cheshire WP, Fealey RD. Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management. Drug Saf. 2008;31(2):109–26
  • . Coskun M, Kaya I. Painful muscle cramps possibly associated with withdrawal from methylphenidate. J Child Adolesc Psychopharmacol. 2016;26(7):658–9.
  • Coskun M, Adak I, Akaltun I. Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine. J Clin Psychopharmacol. 2014;34(4):537–8.
  • Coskun M. Methylphenidate induced obsessive-compulsive symptoms treated with sertraline. Bull Clin Psychopharmacol. 2011;21(3):275–6.
  • Kaya I, Coskun M. Diffuse maculopapular rash with increasing dosage of methylphenidate. J Clin Psychopharmacol. 2016;36(1):106–7.
  • Coskun M, Tutkunkardas MD, Zoroglu S. OROS methylphenidate-induced skin eruptions. J Child Adolesc Psychopharmacol. 2009;19(5):593–4.
  • Coskun M, Zoroglu S. A report of two cases of sexual side effects with OROS methylphenidate. J Child Adolesc Psychopharmacol. 2009;19(4):477–9.
  • Coskun M, Zoroglu S. Tactile and visual hallucinations in a child with methylphenidate and fluoxetine combination. J Clin Psychopharmacol. 2008;28(6):723–5.
  • Green WH. Sympathomimetic amines and central nervous system stimulants. Child and Adolescent Clinical Psychopharmacology, 4. ed. Philadelphia: Lippincott Williams & Wilkins; 2007:55–90.
  • Patel V, Krishna AS, Lefevre C, Kaagaza M, Wittkamp M. Methylphenidate Overdose causing secondary polydipsia and severe hyponatremia in an 8-year-old boy. Pediatr Emerg Care. DOI: 10.1097/PEC.0000000000000788
  • Hassanian-Moghaddam H, Ranjbar M, Farnaghi F, Zamani N, Alizadeh AM, Sarjami S. Stimulant Toxicity in Children: A Retrospective Study on 147 Patients. Pediatr Crit Care Med. 2015;16(8):290–6.
  • Khajehpiri Z, Mahmoudi-Gharaei J, Faghihi T, Karimzadeh I, Khalili H, Mohammadi M. Adverse reactions of methylphenidate in children with attention deficit-hyperactivity disorder: report from a referral center. J Res Pharm Pract. 2014;3(4):130–6
  • . The US Food and Drug Administration [Internet]. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021121s015s017l.pdf [accessed 22 July 2016].
There are 14 citations in total.

Details

Subjects Health Care Administration
Journal Section CASE REPORT
Authors

İbrahim Adak

İlyas Kaya

Murat Coşkun

Publication Date December 30, 2016
Acceptance Date December 26, 2016
Published in Issue Year 2017 Volume: 22 Issue: 1

Cite

Vancouver Adak İ, Kaya İ, Coşkun M. Methylphenidate Induced Hyperhidrosis in an Adolescent Boy. Anatolian Clin. 2016;22(1):50-3.

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