Disseminated Peritoneal Leiomyomatosis with Malignant Transformation

Year 2018, Volume: 23 Issue: 1, 51 - 54, 18.01.2018

Semra Gürünlüoğlu Nusret Akpolat Nihal Bozdağ Kaplan

https://doi.org/10.21673/anadoluklin.322502

Abstract

Disseminated peritoneal leiomyomatosis is a rare disease characterized by presence of multiple smooth muscle nodules throughout the peritoneal cavity. It may mimic malignancies and may rarely undergo malignant transformation. In this paper, we present a 36-year-old female patient who had been diagnosed with cellular leiomyoma after myomectomy. The patient was diagnosed with leiomyomatosis following the pathological examination of the excised nodules that recurred during the clinical follow-up and with leiomyosarcoma during the subsequent recurrences.

Keywords

peritoneum, leiomyomatosis, malignant, myomectomy

Malign Transformasyon Gösteren Dissemine Peritoneal Leiyomiyomatoz

Abstract

Dissemine peritoneal leiyomiyomatoz nadir bir hastalıktır. Peritoneal kavite boyunca multipl düz kas nodüllerinin varlığı ile karakterizedir. Dissemine maligniteleri taklit edebilir. Nadiren de malign transformasyon gösterebilir. Bu yazıda miyomektomi sonrasında selüler leiyomiyom tanısı alan 36 yaşında bir kadın hasta sunulmaktadır. Hasta, klinik takip sırasında tekrarlayan ve eksize edilen nodüllerin patolojik incelemelerinde peritoneal leiyomiyomatoz, sonraki nükslerde leiyomiyosarkom tanısı almıştır.

Keywords

periton, leiyomiyomatoz, malign, miyomektomi

References

• KAYNAKLAR 1. Herrero J, Kamali P, Kirschbaum M. Leiomyomatosis peritonealis disseminata associated with endometriosis:a case report and literature review. European Journal of Obstetrics & Gynecology and Reproductive Biology 76 (1998) 189-191 2. Ordulu Z, Cin PD, Chong WWS, Choy KW, Lee C, Muto MG, Quade BJ, Morton CC. Disseminated peritoneal leiomyomatosis after laparoscopic supracervical histerectomy with characteristic molecular cytogenetic findings of uterine leiomyoma. Genes Chromosomes & Cancer 49: 1152-1160 (2010) 3. Thian YL, Tan KH, Kwek JW, Wang J, Chern B, Yam KL. Leiomyomatosis peritonealis disseminata and subcutaneous myoma- a rare complication of laparoscopic myomectomy. Abdominal İmaging (2009); 34:235-238 4. Sharma P, Chaturvedi KU, Gupta R, Nigam S. Leiomyomatozis peritonealis disseminata with malignant change in a postmenapausal women. Gynecologic Oncology 95 (2004); 742-7 5. Bekkers RLM, Willemsen WNP, Schijf CPT, Massuger LFAG, Bulten J, and Merkus J MWM. Leiomyomatosis Peritonealis Disseminata: Does Malignant Transformation Occur? A Literature Review. Gynecologic Oncology 75, 158–163 (1999) 6. İver Lausen, Ole JJensen, Elo Andersen, and Finn Lindhal. Disseminated peritoneal leiomyomatosis with malignant change in a male. Virshows Archiv A Pathol. Anat (1990) 417: 173-175 7. Randrianjafisamindrakotroka NS, Baldauf JJ, Philippe E, Ritter J, Collin D and Kaemmerlen C. Leiomyomatosis Peritonealis Disseminata Report on Two Cases and Differential Diagnosis with Peritoneal Metastases of a Low-grade Stromal Sarcoma of the Ovary. Path. Res. Pract. 191, 1252-1257 (1995) 8. Kumar S, Sharma JB, Verma D, Gupta P, Roy KK, Malhotra N. Disseminated peritoneal leiomyomatosis: an unusual complication of laparoscopic myomektomi. Arch gynecolobstet (2008); 278:93-95