The Role of Exercise as a Treatment and Preventive Strategy during Covid-19 Pandemic

Year 2020, Issue: Special Issue on COVID 19, 238 - 245, 20.03.2020

Meltem Yalçın , Elif Koçak , Mehtap Kacar

https://doi.org/10.21673/anadoluklin.731902

Cited By: 3

Abstract

On 11 March 2020, World Health Organization has made the assessment that COVID-19 can be characterized as a pandemic. COVID-19 is a usually self-limited infection but it can be present a severe and fatal disease in patients with comorbitidies and the elderly. The characteristics of the virus and general health condition of the host determine disease progression. Scientists have been investigating on the pathophysiology of this disease, diagnostic tools, effective treatment protocols, and the development a vaccine. Preventive strategies are as important as the treatment modalities. This review focuses on the pathophysiological mechanisms of COVID-19, in addition to the roles of exercise in the immunomodulatory mechanisms, host defense systems, and also prevention and treatment of COVID-19. Exercise exerts many important effects such as immunomodulation, augmented defense system on the immune system via mainly muscle derived myokines and increased cardiorespiratory endurance. COVID- 19 pandemic once again demonstrated the importance of prophylactic approaches such as healthy life, maintaining and strengthening of health, and immune system modulation. This pandemic may start a period in which humanity prioritizes healthy living principles, functional foods, maintaining health and welfare approaches, and increased effort to develop and maintain them.

Keywords

Covid-19 pandemic, , pathophysiology, , immune system, exercise, myokines

Covid-19 Salgınında Egzersizin Bir Tedavi ve Önleyici Strateji Olarak Rolü

Abstract

11 Mart 2020’de Dünya Sağlık Örgütü (WHO) COVID-19 küresel salgınını ilan etti. COVID-19 genellikle kendi kendini sınırlayan bir enfeksiyon olduğu halde yaşlılarda ve komorbiditesi olan bireylerde çok daha ciddi ve ölümcül seyretmektedir. Virüsün özellikleri ve konağın genel sağlık durumu hastalığın nasıl seyredeceğini belirlemektedir. Bilim adamları bu hastalığın fizyopatolojisini açıklamak, teşhis yöntemlerini, etkili tedavi protokollerini ve aşısını geliştirmek için çalışıyorlar. Önleyici stratejiler tedavi yöntemleri kadar önemlidir. Bu derleme COVID-19 fizyopatolojisine, ve egzersizin immünomodülatör mekanizmalarda, konakçı savunma sistemlerinde ve COVID-19’un önlenmesinde ve tedavisindeki rollerine odaklanmaktadır. Egzersiz kardiyopulmoner dayanıklılığı ve kaslardan miyokinlerin üretimini artırarak immün sistemi güçlendirir ve immün yanıtı düzenler. COVID-19 salgını, sağlıklı yaşam, sağlığın korunması ve güçlendirilmesi ve bağışıklık sistemi modülasyonu gibi profilaktik yaklaşımların önemini bir kez daha göstermiştir. Bu salgın, insanoğlunun sağlıklı yaşam prensiplerini, fonksiyonel gıdaları, sağlığını korumayı ve refah yaklaşımlarını daha ön planda tuttuğu, ve bunları geliştirme ve sürdürme çabalarının arttığı bir dönemi başlatabilir.

Keywords

Covid-19 pandemisi, fizyopatoloji, immun sistem, egzersiz, myokin

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