Gonokokkal enfeksiyonlar ve tedavisi

Birgul Kacmaz

doi:10.38053/agtd.590724

Review

Gonokokkal enfeksiyonlar ve tedavisi

Year 2019, Volume: 1 Issue: 4, 105 - 109, 22.09.2019

Birgul Kacmaz

https://doi.org/10.38053/agtd.590724

Abstract

ÖZ

Gonore Neisseria gonorrhoeae’nin neden olduğu ikinci en sık rapor edilen
cinsel yolla bulaşan enfeksiyondur. 25 yaşın altındakiler ve yüksek riskli
cinsel davranışları olanlar risk altındadır. Esas olarak enfeksiyon üretra,
serviks, rektum, farenks ve konjunktivanın mukoz membranlarını tutar.
Erkeklerde üretrite, kadınlarda servisite neden olur. Erkekler genellikle
semptomatiktir. Dizüri ve penil akıntı en sıklıkla görülür. Kadınların %95’i
semptomsuzdur. Semptomatik olgularda ise klinik genelikle hafiftir ve akut
sistiti veya vaginiti taklit eder. Gram boyama, kültür ve nükleik asit
amplifikasyon testleri ile tanı konulabilir. Hastalar genellikle Chlamidya trachomatis ile birlikte
enfektedir. Bu nedenle kombine tedavi önerilmektedir. Komplike olmayan
servikal, üretral, anorektal ve farengeal infeksiyonların tedavisinde
seftriaksonla (250 mg intramuskuler tek doz) birlikte ya azitromisin (1 g oral
tek doz), veya doksisiklin (100 mg günde iki kez yedi gün) etkindir.

Keywords

Gonore, klinik özellikler, tanı, tedavi

References

1. Workowski KA, Bolan GA. Sexually transmitted disease treatment quidelines, 2015. MMWR Recomm Rep. 2015; 64: 1-137.
2. Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance, 2016. Atlanta, GA: US Department of Health and Human Services; 2017.
3. Satterwhite CL, Torrone E, Meites E, Dunne EF, Mahajan R, Ocfemia MC, Su J, Xu F, Weinstock H. Sexually transmitted infections among US women and men: prevalence and incidence estimates, 2008. Sex Transm Dis. 2013; 40:187-93.
4. T.C. Sağlık Bakanlığı Bulaşıcı Hastalıkların İhbarı ve Bildirim Sistemi standart tanı, sürveyans ve laboratuvar rehberi-2004.
5. Zarakolu P, Sakızlıgil B, Cakır B, Unal S. The point prevalence of gonorrhoea among registered sex workers in Ankara, Turkey. Int J STD AIDS 2002; 13: 52.
6. Türkiye’de Cinsel Yolla Bulaşan Enfeksiyonlar ve HIV Sürveyansı Hizmet Projesi. Özet raporu, Nisan 2007, Avrupa Birliği, ICON-INSTITUT Public Sector GmbH, Ankara Hacettepe Üniversitesi, Antwerp Institute of Tropical Medicine.
7. Workowski KA, Berman S. Centers for Disease Control and Prevention (CDC). Sexually transmitted diseases treatment guidelines, 2010 MMWR Recomm Rep 2010; 59: 1-110.
8. U. S. Preventive Services Task Force. Screening for gonorrhea: recommendation statement. Ann Fam Med 2005; 3; 263-7.
9. Kılıç A, Başustaoğlu AC. Neisseria türleri. In: Topçu Wilke A (eds) Enfeksiyon Hastalıkları ve Mikrobiyolojisi. Nobel Tıp Kitabevleri 4. Baskı, İstanbul, 2017: 1841-50.
10. MM, Jeanne, AA Michael. Neisseria gonorrhoeae (Gonorrhea). In: Bennett JE, Dolin R, Blaser JB (ed). Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 8th edition. Philadelphia: Elsevier, 2015:2446-61.
11. Mayor MT, Roett MA, Udurihi KA. Diagnosis and management of gonococcal infections. Am Fam Physician 2012; 86: 931-8.
12. Huppert JS, Biro F, Lan D, Mortensen JE, Reed J, Slap GB. Urinary symptoms in adolescent females: STI or UTI? J Adolesc Health 2007; 40: 418-24.13. Judson FN, Ruder MA. Effect of hysterectomy on genital infections. Br J Vener Dis 1979; 55: 434-8.
14. Javanbakht M, Gorbach P, Stirland A, Chien M, Kerndt P, Guerry S. Prevalence and correlates of rectal Chlamydia and gonorrhea among female clients at sexually transmitted disease clinics. Sex Transm Dis 2012; 39: 917-22.
15. de Vries HJ, Zingoni A, White JA, Rosss JD, Kreater A. 2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens Int J STD AIDS 2013; 25: 465-74.
16. UpToDate, www.uptodate.com, Marrazzo J, Bloom A. Jul 23, 2018.
17. Pogany L, Romanowski B, Robinson J, et al. Management of gonococcal infection among adults and youth. Can Fam Physician 2015; 61: 869-73.
18. Zarakolu P, Sakızlıgil B, Ünal S: Ankara ilindeki seks çalışanlarından izole edilen Neisseria gonorrhoeae suşlarının antimikrobiyallere karşı direnç durumu. Mikrob Bülteni 2006; 40: 69-74.
19. Aydın D, Küçükbasmacı Ö, Gönüllü N, Aktaş Z. Susceptibilities of Neisseria gonorrhoeae and Ureaplasma urealyticum Isolates from male patients with urethritis to several antibiotics including telithromycin. Chemotherapy 2005; 51: 89-92.

Year 2019, Volume: 1 Issue: 4, 105 - 109, 22.09.2019

Birgul Kacmaz

https://doi.org/10.38053/agtd.590724

Abstract

References

1. Workowski KA, Bolan GA. Sexually transmitted disease treatment quidelines, 2015. MMWR Recomm Rep. 2015; 64: 1-137.
2. Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance, 2016. Atlanta, GA: US Department of Health and Human Services; 2017.
3. Satterwhite CL, Torrone E, Meites E, Dunne EF, Mahajan R, Ocfemia MC, Su J, Xu F, Weinstock H. Sexually transmitted infections among US women and men: prevalence and incidence estimates, 2008. Sex Transm Dis. 2013; 40:187-93.
4. T.C. Sağlık Bakanlığı Bulaşıcı Hastalıkların İhbarı ve Bildirim Sistemi standart tanı, sürveyans ve laboratuvar rehberi-2004.
5. Zarakolu P, Sakızlıgil B, Cakır B, Unal S. The point prevalence of gonorrhoea among registered sex workers in Ankara, Turkey. Int J STD AIDS 2002; 13: 52.
6. Türkiye’de Cinsel Yolla Bulaşan Enfeksiyonlar ve HIV Sürveyansı Hizmet Projesi. Özet raporu, Nisan 2007, Avrupa Birliği, ICON-INSTITUT Public Sector GmbH, Ankara Hacettepe Üniversitesi, Antwerp Institute of Tropical Medicine.
7. Workowski KA, Berman S. Centers for Disease Control and Prevention (CDC). Sexually transmitted diseases treatment guidelines, 2010 MMWR Recomm Rep 2010; 59: 1-110.
8. U. S. Preventive Services Task Force. Screening for gonorrhea: recommendation statement. Ann Fam Med 2005; 3; 263-7.
9. Kılıç A, Başustaoğlu AC. Neisseria türleri. In: Topçu Wilke A (eds) Enfeksiyon Hastalıkları ve Mikrobiyolojisi. Nobel Tıp Kitabevleri 4. Baskı, İstanbul, 2017: 1841-50.
10. MM, Jeanne, AA Michael. Neisseria gonorrhoeae (Gonorrhea). In: Bennett JE, Dolin R, Blaser JB (ed). Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 8th edition. Philadelphia: Elsevier, 2015:2446-61.
11. Mayor MT, Roett MA, Udurihi KA. Diagnosis and management of gonococcal infections. Am Fam Physician 2012; 86: 931-8.
12. Huppert JS, Biro F, Lan D, Mortensen JE, Reed J, Slap GB. Urinary symptoms in adolescent females: STI or UTI? J Adolesc Health 2007; 40: 418-24.13. Judson FN, Ruder MA. Effect of hysterectomy on genital infections. Br J Vener Dis 1979; 55: 434-8.
14. Javanbakht M, Gorbach P, Stirland A, Chien M, Kerndt P, Guerry S. Prevalence and correlates of rectal Chlamydia and gonorrhea among female clients at sexually transmitted disease clinics. Sex Transm Dis 2012; 39: 917-22.
15. de Vries HJ, Zingoni A, White JA, Rosss JD, Kreater A. 2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens Int J STD AIDS 2013; 25: 465-74.
16. UpToDate, www.uptodate.com, Marrazzo J, Bloom A. Jul 23, 2018.
17. Pogany L, Romanowski B, Robinson J, et al. Management of gonococcal infection among adults and youth. Can Fam Physician 2015; 61: 869-73.
18. Zarakolu P, Sakızlıgil B, Ünal S: Ankara ilindeki seks çalışanlarından izole edilen Neisseria gonorrhoeae suşlarının antimikrobiyallere karşı direnç durumu. Mikrob Bülteni 2006; 40: 69-74.
19. Aydın D, Küçükbasmacı Ö, Gönüllü N, Aktaş Z. Susceptibilities of Neisseria gonorrhoeae and Ureaplasma urealyticum Isolates from male patients with urethritis to several antibiotics including telithromycin. Chemotherapy 2005; 51: 89-92.

There are 18 citations in total.

Details

Primary Language	Turkish
Subjects	Health Care Administration
Journal Section	Review
Authors	Birgul Kacmaz 0000-0002-5190-7249
Publication Date	September 22, 2019
Published in Issue	Year 2019 Volume: 1 Issue: 4

Cite

APA	Kacmaz, B. (2019). Gonokokkal enfeksiyonlar ve tedavisi. Anadolu Güncel Tıp Dergisi, 1(4), 105-109. https://doi.org/10.38053/agtd.590724
AMA	Kacmaz B. Gonokokkal enfeksiyonlar ve tedavisi. Anatolian Curr Med J. September 2019;1(4):105-109. doi:10.38053/agtd.590724
Chicago	Kacmaz, Birgul. “Gonokokkal Enfeksiyonlar Ve Tedavisi”. Anadolu Güncel Tıp Dergisi 1, no. 4 (September 2019): 105-9. https://doi.org/10.38053/agtd.590724.
EndNote	Kacmaz B (September 1, 2019) Gonokokkal enfeksiyonlar ve tedavisi. Anadolu Güncel Tıp Dergisi 1 4 105–109.
IEEE	B. Kacmaz, “Gonokokkal enfeksiyonlar ve tedavisi”, Anatolian Curr Med J, vol. 1, no. 4, pp. 105–109, 2019, doi: 10.38053/agtd.590724.
ISNAD	Kacmaz, Birgul. “Gonokokkal Enfeksiyonlar Ve Tedavisi”. Anadolu Güncel Tıp Dergisi 1/4 (September 2019), 105-109. https://doi.org/10.38053/agtd.590724.
JAMA	Kacmaz B. Gonokokkal enfeksiyonlar ve tedavisi. Anatolian Curr Med J. 2019;1:105–109.
MLA	Kacmaz, Birgul. “Gonokokkal Enfeksiyonlar Ve Tedavisi”. Anadolu Güncel Tıp Dergisi, vol. 1, no. 4, 2019, pp. 105-9, doi:10.38053/agtd.590724.
Vancouver	Kacmaz B. Gonokokkal enfeksiyonlar ve tedavisi. Anatolian Curr Med J. 2019;1(4):105-9.

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