DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI

İbrahim Üçgül; Sultan Aras

DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI

Öz

Deselülerize edilmiş doku ve organlar çeşitli doku mühendisliği ve rejeneratif tıp uygulamalarında başarıyla kullanılmaktadır. Ekstraselüler matristen elde edilen biyolojik bir iskele, işlem görecek dokudan hücreleri etkin bir şekilde ortadan kaldıran çeşitli deselülerizasyon yöntemleri ile üretilebilir. Kullanılan deselülerizasyon yöntemleri dokuların ve organların yapısına göre değişir. Hücrelerin bir dokudan çıkarılması, dokunun kaynağına ve kullanılan spesifik fiziksel, kimyasal ve enzimatik yöntemlere bağlıdır. Bu yöntemlerin her biri geri kalan hücre dışı matrisin (ECM) yapısındaki biyokimyasal bileşimini, dokunun ince yapısını (ultrastrüktürünü) ve mekanik davranışını etkiler. Bu makalede en sık kullanılan deselülerizasyon yöntemleri tanıtılarak ve bu yöntemlerin biyolojik doku iskelesi materyali üzerindeki etkileri ele alınmaktadır.

Anahtar Kelimeler

Deselülerizasyon,Ekstraselüler Matris,Doku mühendisliği (TE)

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Details

Primary Language

Turkish

Subjects

Engineering

Journal Section

Review

Authors

İbrahim Üçgül
SÜLEYMAN DEMİREL ÜNİVERSİTESİ
Türkiye

Sultan Aras
Türkiye

Publication Date

December 29, 2017

Submission Date

November 16, 2017

Acceptance Date

November 28, 2017

Published in Issue

Year 1970 Volume: 2 Number: 2

IZ

https://izlik.org/JA26ZX46LR

Cite

RIS / Bibtex

APA

Üçgül, İ., & Aras, S. (2017). DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi, 2(2), 19-34. https://izlik.org/JA26ZX46LR

AMA

1.Üçgül İ, Aras S. DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi. 2017;2(2):19-34. https://izlik.org/JA26ZX46LR

Chicago

Üçgül, İbrahim, and Sultan Aras. 2017. “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”. Anka E-Dergi 2 (2): 19-34. https://izlik.org/JA26ZX46LR.

EndNote

Üçgül İ, Aras S (December 1, 2017) DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi 2 2 19–34.

IEEE

[1]İ. Üçgül and S. Aras, “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”, Anka E-Dergi, vol. 2, no. 2, pp. 19–34, Dec. 2017, [Online]. Available: https://izlik.org/JA26ZX46LR

ISNAD

Üçgül, İbrahim - Aras, Sultan. “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”. Anka E-Dergi 2/2 (December 1, 2017): 19-34. https://izlik.org/JA26ZX46LR.

JAMA

1.Üçgül İ, Aras S. DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi. 2017;2:19–34.

MLA

Üçgül, İbrahim, and Sultan Aras. “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”. Anka E-Dergi, vol. 2, no. 2, Dec. 2017, pp. 19-34, https://izlik.org/JA26ZX46LR.

Vancouver

1.İbrahim Üçgül, Sultan Aras. DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi [Internet]. 2017 Dec. 1;2(2):19-34. Available from: https://izlik.org/JA26ZX46LR