DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI

İbrahim Üçgül; Sultan Aras

DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI

Öz

Deselülerize edilmiş doku ve organlar çeşitli doku mühendisliği ve rejeneratif tıp uygulamalarında başarıyla kullanılmaktadır. Ekstraselüler matristen elde edilen biyolojik bir iskele, işlem görecek dokudan hücreleri etkin bir şekilde ortadan kaldıran çeşitli deselülerizasyon yöntemleri ile üretilebilir. Kullanılan deselülerizasyon yöntemleri dokuların ve organların yapısına göre değişir. Hücrelerin bir dokudan çıkarılması, dokunun kaynağına ve kullanılan spesifik fiziksel, kimyasal ve enzimatik yöntemlere bağlıdır. Bu yöntemlerin her biri geri kalan hücre dışı matrisin (ECM) yapısındaki biyokimyasal bileşimini, dokunun ince yapısını (ultrastrüktürünü) ve mekanik davranışını etkiler. Bu makalede en sık kullanılan deselülerizasyon yöntemleri tanıtılarak ve bu yöntemlerin biyolojik doku iskelesi materyali üzerindeki etkileri ele alınmaktadır.

Anahtar Kelimeler

Deselülerizasyon,Ekstraselüler Matris,Doku mühendisliği (TE)

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Mühendislik

Bölüm

Derleme

Yazarlar

İbrahim Üçgül
SÜLEYMAN DEMİREL ÜNİVERSİTESİ
Türkiye

Sultan Aras
Türkiye

Yayımlanma Tarihi

29 Aralık 2017

Gönderilme Tarihi

16 Kasım 2017

Kabul Tarihi

28 Kasım 2017

Yayımlandığı Sayı

Yıl 1970 Cilt: 2 Sayı: 2

IZ

https://izlik.org/JA26ZX46LR

Kaynak Göster

RIS / Bibtex

APA

Üçgül, İ., & Aras, S. (2017). DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi, 2(2), 19-34. https://izlik.org/JA26ZX46LR

AMA

1.Üçgül İ, Aras S. DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi. 2017;2(2):19-34. https://izlik.org/JA26ZX46LR

Chicago

Üçgül, İbrahim, ve Sultan Aras. 2017. “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”. Anka E-Dergi 2 (2): 19-34. https://izlik.org/JA26ZX46LR.

EndNote

Üçgül İ, Aras S (01 Aralık 2017) DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi 2 2 19–34.

IEEE

[1]İ. Üçgül ve S. Aras, “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”, Anka E-Dergi, c. 2, sy 2, ss. 19–34, Ara. 2017, [çevrimiçi]. Erişim adresi: https://izlik.org/JA26ZX46LR

ISNAD

Üçgül, İbrahim - Aras, Sultan. “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”. Anka E-Dergi 2/2 (01 Aralık 2017): 19-34. https://izlik.org/JA26ZX46LR.

JAMA

1.Üçgül İ, Aras S. DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi. 2017;2:19–34.

MLA

Üçgül, İbrahim, ve Sultan Aras. “DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI”. Anka E-Dergi, c. 2, sy 2, Aralık 2017, ss. 19-34, https://izlik.org/JA26ZX46LR.

Vancouver

1.İbrahim Üçgül, Sultan Aras. DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi [Internet]. 01 Aralık 2017;2(2):19-34. Erişim adresi: https://izlik.org/JA26ZX46LR