Enfeksiyon Kaynağı Vektörlerden Korunma

Abstract

Vektör kaynaklı hastalıklar, dünya genelinde ciddi halk sağlığı sorunları arasında yer almaktadır. İklim değişikliği başta olmak üzere küreselleşme ve kentleşme gibi faktörler, vektörlerin biyocoğrafik dağılımını ve dolayısı ile hastalık etkenlerinin yayılımını doğrudan etkilemektedir. Vektörlerden korunma, bu hastalıkların önlenmesinde en etkili stratejidir. Bu derlemede; kene, sivrisinek ve kum sineği gibi önemli eklem bacaklı vektörlerden korunmaya yönelik bireysel, kimyasal, biyolojik ve çevresel müdahale yöntemleri ele alınmış, vektör kontrol stratejilerinin ve halkın bilinçlendirilmesinin önemi vurgulanmıştır.

Keywords

• Vektör
• Vektör-kaynaklı enfeksiyonlar
• Korunma

Prevention of Vector-Borne Infection Sources

Abstract

Vector-borne diseases are among the serious public health concerns worldwide. Climate change, globalization, and urbanization influence the biogeographical distribution of vectors and consequently affect the transmission dynamics of vector-borne pathogens. Vector protection is the most effective strategy for the prevention of these diseases. In this review; individual, chemical, biological and environmental intervention methods for prevention against key arthropod vectors such as ticks, mosquitoes, and sand flies are discussed, as well as the necessity of vector control measures and public awareness is emphasized.

Keywords

• Vector
• Vector-borne infections
• Prevention

References

1. 1. Bourtzis K, Dobson SL, Xi Z, et al. Harnessing Mosquito-Wolbachia Symbiosis for Vector and Disease Control. Acta Trop. 2014;132(Suppl):S150-63.
2. 2. Chikungunya. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/chikungunya, (erişim tarihi: 12.04.2025).
3. 3. Crimean-Congo haemorrhagic fever. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/crimean-congo-haemorrhagic-fever#:~:text=Crimean%2DCongo%20haemorrhagic%20fever%20(CCHF)%20is%20a%20widespread%20disease,rate%20of%2010%E2%80%9340%25, (erişim tarihi: 12.04.2025).
4. 4. Çetin H, Özbel Y. Kum Sinekleri (Yakarca, Tatarcık) ve Kontrol Yöntemleri. Turkiye Parazitol Derg. 2017;41:102-13.
5. 5. de Souza WM, Weaver SC. Effects of climate change and human activities on vector-borne diseases. Nat Rev Microbiol. 2024; 22, 476-91. https://doi.org/10.1038/s41579-024-01026-0.
6. 6. Dengue and severe dengue. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue, (erişim tarihi: 12.04.2025).
7. 7. Ebani VV, Mancianti F. Entomopathogenic fungi and bacteria in a veterinary perspective. Biology. 2021; 10: 479. https://doi.org/10.3390/ biology10060479.
8. 8. Ergünay K, Polat C, Özkul A. Vector-borne viruses in Turkey: A systematic review and bibliography. Antiviral Res. 2020;183:104934.

9. 9. Geographic distribution of Crimean-Congo Haemorrhagic Fever. World Health Organization, https://www.who.int/multi-media/details/geographic-distribution-of-crimean-congo-haemorrhagic-fever (erişim tarihi: 22.04.2025).
10. 10. Ghazanfar MU, Raza M, Raza W, et al. Trichoderma as potential biocontrol agent, its exploitation in agriculture: a review. Plant Protection. 2018; 2(3): 109-135.
11. 11. Hyalomma marginatum - current known distribution: October 2023. European Centre for Disease Prevention and Control (ECDC), https://ecdc.europa.eu/en/disease-vectors/surveillance-and-disease-data/tick-maps, (erişim tarihi: 25.04.2025).
12. 12. Invasive mosquitoes. European Centre for Disease Prevention and Control (ECDC), https://www.ecdc.europa.eu/en/disease-vectors/surveillance-and-disease-data/invasive-mosquito-maps, (erişim tarihi: 25.04.2025).
13. 13. Jamil M, Latif N, Gul J, et al. A review: An insight into the potential of biological control of ticks in domestic and wild animals. AJLS. 2022;5(2):51-67. doi:10.34091/AJLS.5.2.6 13.
14. 14. Kean J, Rainey SM, McFarlane M, et al. Fighting Arbovirus Transmission: Natural and Engineered Control of Vector Competence in Aedes Mosquitoes. Insects. 2015;6:236-78.
15. 15. Leishmaniasis. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/leishmaniasis, (erişim tarihi: 12.04.2025).
16. 16. Makwarela TG, Seoraj-Pillai N, Nangammbi TC. Tick Control Strategies: Critical Insights into Chemical, Biological, Physical, and Integrated Approaches for Effective Hard Tick Management. Veterinary Sciences. 2025;12(2):114. https://doi.org/10.3390/vetsci12020114
17. 17. Malaria. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/malaria, (erişim tarihi: 12.04.2025).
18. 18. Marciano AF, Mascarin F, Franco R, et al. Innovative granular formulation of Metarhizium robertsii microsclerotia and blastospores for cattle tick control. Sci Rep. 2021;11:4972. https://doi.org/10.1038/ s41598-021-84142-8.
19. 19. Mascarin G, Lopes R, Delaliber I, et al. Current status and perspectives of fungal entomopathogens used for microbial control of arthropod pests in Brazil. J Invertebr Pathol. 2019;165:46-53. https://doi. org/10.1016/j.jip.2018.01.001.
20. 20. Moretti R, Lim JT, Ferreira AGA, et al. Exploiting Wolbachia as a Tool for Mosquito-Borne Disease Control: Pursuing Efficacy, Safety, and Sustainability. Pathogens. 2025;14(3):285. doi: 10.3390/pathogens14030285.
21. 21. Mutebi JP, Gimnig J. Mosquitoes, Ticks & Other Arthropods, “Centers for Disease Control and Prevention: CDC Yellow Book 2024: Health Information for International Travel”. Oxford University Press (2023).
22. 22. Native mosquitoes. European Centre for Disease Prevention and Control (ECDC), https://www.ecdc.europa.eu/en/disease-vectors/surveillance-and-disease-data/native-mosquito-maps, (erişim tarihi: 25.04.2025).
23. 23. Özbel Y, Töz S, Kitapçıoğlu G, Şark Çıbanı Kutanöz Leishmaniasis, 1. baskı, Meta Basım Matbaacılık Hizmetleri, İzmir (2019).
24. 24. Phlebotomine sand flies - Factsheet for experts. European Centre for Disease Prevention and Control (ECDC), https://www.ecdc.europa.eu/en/disease-vectors/facts/phlebotomine-sand-flies, (erişim tarihi: 25.04.2025).
25. 25. Pimentel AC, Cesar CS, Martins M, Cogni, R. The Antiviral Effects of the Symbiont Bacteria Wolbachia in Insects. Front Immunol. 2020;11:626329.
26. 26. Smith Jr, Jackson P. Effects of insecticidal placement on non-target arthropods in the peanut ecosystem. Peanut Sci. 1975;2(2):87-90. https://doi.org/10.3146/i0095-3679-2-2-13
27. 27. Sullivan CF, Parker BL, Skinner M. A review of commercial Metarhizium-and Beauveria-based biopesticides for the biological control of ticks in the USA. Insects. 2022;13(3):260. doi:10.3390/ insects13030260.
28. 28. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Chikungunya Ateşi, “Doğanay M, Şahin M, Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 170-3, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
29. 29. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Dengue virüsü enfeksiyonu, “Doğanay M, Şahin M, Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 161-169, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
30. 30. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Kırım Kongo kanamalı ateşi, “Doğanay M, Şahin M,Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 81-96, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
31. 31. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Leishmaniasis. “Doğanay M, Şahin M, Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 182-92, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
32. 32. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Lyme hastalığı, “Doğanay M, Şahin M, Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 205-8, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
33. 33. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Sarı Humma. “Doğanay M, Şahin M, Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 174-9, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
34. 34. T.C. Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü. Tularemi, “Doğanay M, Şahin M, Topluoğlu S (eds): Türkiye Zoonotik Hastalıklar Eylem Planı (2019-2023)” kitabında s. 71-80, Artı6 Medya Tanıtım Matbaa Ltd. Şti., Ankara (2019).
35. 35. Thomson MC, Stanberry LR. Climate change and vectorborne diseases. N Engl J Med, 2022;387:1969-78.
36. 36. Uzun S, Gurel MS, Harman M. Kutanoz layşmanyazis tanı ve tedavi rehberi, Turk Dermatoloji Dergisi Tanı ve Tedavi Rehberleri Serisi, Galenos Yayınevi, İstanbul (2017).
37. 37. Vector-borne diseases. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/vector-borne-diseases, (erişim tarihi: 12.04.2025).
38. 38. Velez ID, Uribe A, Barajas J, et al. Large-Scale Releases and Establishment of wMel Wolbachia in Aedes aegypti Mosquitoes throughout the Cities of Bello, Medellín and Itagüí, Colombia. PLoS Neglected Trop Dis. 2023;17:e0011642.
39. 39. West Nile virus. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/west-nile-virus, (erişim tarihi: 12.04.2025).
40. 40. Wężyk D, Bajer A, Dwużnik-Szarek D. How to get rid of ticks - a mini-review on tick control strategies in parks, gardens, and other human-related environments. Ann Agric Environ Med. 2025;32(1):1-8. doi: 10.26444/aaem/189930.
41. 41. World Health Organization. Control of the leishmaniases: report of a meeting of the WHO Expert Commitee on the Control of Leishmaniases, Geneva, 22-26 March 2010. World Health Organization, Geneva (2010).
42. 42. World Health Organization. Pesticides and their application for the control of vectors and pests of public health importance, 6th ed., World Health Organization, Geneva (2006).
43. 43. Yellow fever. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/yellow-fever, (erişim tarihi: 12.04.2025).
44. 44. Yen PS, Failloux AB. A Review: Wolbachia-Based Population Replacement for Mosquito Control Shares Common Points with Genetically Modified Control Approaches. Pathogens. 2020;9:404.
45. 45. Zika virus. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/zika-virus, (erişim tarihi: 12.04.2025).