İleri Evre Küçük Hücreli Dışı Akciğer Kanserinde Palyatif Amaçlı Tek Doz 10 Gy Tedavi Şemasının Etkinliği

Abstract

Amaç: Biz bu çalışmamızda, ileri evre küçük hücreli dışı akciğer kanserli 17 hastada tek doz 10 Gy tedavisinin palyatif etkinliğini araştırmayı amaçladık. Materyal Metod:Daha önce tedavi görmemiş, genel durumu kötü, ileri evre küçük hücreli dışı 15 hastaya kobalt teleterapi cihazı ile tek fraksiyonda 10 Gy palyatif RT uygulanmıştır. Sonuçlar: Tedavi sonrası öksürük yakınması olan 15 hastanın 8’inde komplet (%53), 3’ünde parsiyel (%20); hemoptizisi olan 8 hastanın tümünde komplet (%100) cevap alındı. Göğüs ağrısı olan 11 hastanın 3’ünde parsiyel (%27) parsiyel cevap alınırken 8 hasta cevapsızdı (%72). Nefes darlığı olan 9 hastanın 5’inde parsiyel (%55) cevap gözlenirken 4 hasta tedaviye cevap vermedi (%45). İleri evre, performansı kötü küçük hücreli dışı akciğer kanserli hastalarda özellikle hemoptizi palyasyonu için tek doz 10 Gy radyoterapi uygulanması rasyonel olabili

Keywords

• Küçük hücreli dışı
• akciğer kanseri
• palyasyon

The Effectivenes of Single Fraction 10 Gy Treatment Planning in Patients with Advanced Non-Small Cell Lung Cancer

Abstract

Purpose: In our study we evaluated the effectivenes of single fraction of 10 Gy radiotherapy on non-small cell lung cancer patients who had symptoms such as cough, pain, hemoptysis and dyspnea. Material and Method: Previously untreated fifteen patients who had advanced non-small cell lung cancer and poor prognostic criterions were irradiated by cobalt 60 with 10 Gy doses in single fraction Results: We observed complete response in 8 patients (%53) and partial response in 3 patients (%20) of total number of 15 having cough symptom. We also had complete response in all the patients with hemoptysis, 8 patients out of 8 (%100). Of 11 patients with chest pain we had 3 were partially responsive (% 55) and 4 non responsive (%45) Delivering single dose radiotherapy can be rational for palliation symptoms especially hemoptysis in advanced non-small cell lung cancer patients who have poor performance status

Keywords

• Non-small cell
• lung cancer
• palliation

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