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Year 2017, Volume: 16 Issue: 1, 35 - 40, 01.05.2017

Hasan Çalışkan Fırat Akat Nezahat Zaloğlu

https://doi.org/10.1501/Ashd_0000000124

Abstract

Anxiety is an emotional situation that include fear and apprehension. To understand the underlying mechanism of anxiety and in order to improve new therapeutic agents, the unconditioned animal anxiety tests are conducted. In this this review, open field test, elevated plus maze and light dark box tests are investigated which are unconditioned tests in general use

Keywords

Anxiety Elevated plus maze Light dark box Open field test Unconditioned anxiety tests

References

  • Andreatini R, Bacellar LF Braz J. The relationship between anxiety and depression in animal models: a study using the forced swimming test and elevated plus-maze. Med Biol Res. 1999; 32(9):1121-6.
  • Arantes R, Tejada J, Bosco GG, Morato S, Roque AC. Mathematical methods to model rodent behavior in the elevated plus-maze. J Neurosci Methods. 2013; 220(2):141-8.
  • Bagewadı HG, Ak AK, Shıvaramegowda RM. An Experimental Study to Evaluate the Effect of Memantine in Animal Models Anxiety in Swiss Albino Mice. J Clin Diagn Res. 2015; 9(8):1-5.
  • Belzung C, Misslin R, Vogel E, Dodd RH, Chapouthier G. Anxiogenic effects of methyl-beta- carboline-3-carboxylate in a light/dark choice situation. Pharmacol Biochem Behav. 1987; 28(1): 29
  • Bourin M, Petit-Demoulière B, Dhonnchadha BN, Hascoet M (2007) . Animal models of anxiety in mice. Fundam Clin Pharmacol. 2007; 21(6): 567-74.
  • Cagni P, Barros M. Cannabinoid type 1 receptor ligands WIN 55,212-2 and AM 251 alter anxiety-like behaviors of marmoset monkeys in an open-field test. Behav Brain Res. 2013; 240: 91-94
  • Candland DK, Nagy ZM. The open field: some comperative data. Annals New York Academy of Sciences. 1969; 159: 831-851.
  • Carobrez AP, Bertoglio LJ. Ethological and temporal analyses of anxiety-like behavior: The elevated plus-maze model 20 years on. Neuroscience and Biobehavioral Reviews. 2005; 29: 1193–1205.
  • Crawley J, Goodwin FK. Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav. 1980; 13(2):167-170.
  • Ehrlıch A, Burns N. Exploratory behaviour of the black footed ferret. Canadian Journal of psychology. ; 12: 235-241. Fıset C, Rıoux FM, Surette ME, Fıset S. Prenatal Iron Deficiency in Guinea Pigs Increases Locomotor Activity but Does Not Influence Learning and Memory. PLoS One. 2015; 10(7): 0133168.
  • Hall CS. Emotional behavior in rat: Defaction and urination as measure of individual diffirences in emotionality. Journal of comparative Psychology. 1934; 18: 385-403.
  • Handley SL, Mıthanı S. Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ’fear’-motivated behaviour. Naunyn Schmiedebergs Arch. Pharmacol. 1984; 327:1-5.
  • Imaizumi M, Miyazaki S, Onodera K. Effects of xanthine derivatives in a light/dark test in mice and contribution of adenosine receptors. Methods Find. Exp. Clin. Pharmacol. 1994; 16: 639–644.
  • Kalueff AV, Tuohımaa P. Experimental modeling of anxiety and depression. Acta Neurobiol Exp. 2004; : 439-448.
  • Korte SM, De Boer SF. A robust animal model of state anxiety: fear-potentiated behaviour in the elevated plus-maze. Eur J Pharmacol. 2003; 463(1-3): 163-175.
  • Kumar V, Bhat ZA, Kumar D. Animal models of anxiety: a comprehensive review. 2013; 68(2): 175
  • Martinek Z, Lat J. Long term stability of individual differences in exploratory behavior and rate of habituation in dogs. Physiol Bohemoslov. 1969; 18: 217–225.
  • Meıjer E, Van Nes A, Back W, Van Der Staay FJ. Clinical effects of buprenorphine on open field behaviour and gait symmetry in healthy and lame weaned piglets. Vet J. 2015; 206(3): 303.
  • Montgomery KC. The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol. 1955; 48(4): 254-260.
  • Mushtaq MY, Marçal RM, Champagne DL, Van Der Kooy F, Verpoorte R, ChoI YH. Effect of acute stresses on zebra fish (Danio rerio) metabolome measured by NMR-based metabolomics. Planta Med. ; 80(14): 1227-1233.
  • Oldham J, Morlock H. The effects of open field size on activity in the mongolian gerbil. Psycohonomic Science. 1970; 20: 290.
  • Pedernera-Romano C, Ruız De La Torre JL, Badıella L, Manteca X. Effect of perphenazine enanthate on open-field test behaviour and stress-induced hyperthermia in domestic sheep. Pharmacol Biochem Behav. 2010; 94(3): 329-332.
  • Pellow S, Chopin P, File SE, Briley M. Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci Methods. 1985; 14: 149-167.
  • Porsolt RD, Le Pıchon M, Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature. 1977; , 266(5604): 730-732.
  • Porsolt RD, Anton G, Blavet N, Jalfre M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol. 1978a; 47(4): 379-391.
  • Porsolt RD, Bertın A, Jalfre M. “Behavioural despair” in rats and mice: strain differences and the effects of imipramine. Eur J Pharmacol. 1978b; 51: 291-294.
  • Prut I, Belzung C. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. European Journal of Pharmacology. 2003; 463: 3-33.
  • Sayapina NV, Batalova TA, Chaıka VV et al. Multi-walled carbon nanotubes increase anxiety levels in rats and reduce exploratory activity in the open field test. Dokl Biol Sci. 2015; 464(1): 223-225.
  • Soubrie P. Open field chez le rat: interrelations entre locomotion exploration et emotivite. J. Pharmacol. ; 2: 457-472. Stahl SM (2015). Stahl’ın Temel Psikofarmakolojisi, Sinirbilimsel Temeli ve Pratik Uygulaması. Ed:
  • Prof.Dr. Tunç Alkın. S. : 388-420. Wall PM, Messier C. Methodological and conceptual issues in the use of the elevated plus-maze as a psychological measurement instrument of animal anxiety-like behavior. Neurosci Biobehav Rev. 2001; (3): 275-286.
  • Walsh RN, Cummimis RA. The open-field test A critical review. Psychological Bulletin. 1976; 83: 482
  • Zimbardo PF, Montgomery KC. Effects of free environment rearing upon exploratory behavior. Psychological Repoils. 1957; 3: 589-594.

Şartsız Hayvan Anksiyete Testleri

Year 2017, Volume: 16 Issue: 1, 35 - 40, 01.05.2017

Hasan Çalışkan Fırat Akat Nezahat Zaloğlu

https://doi.org/10.1501/Ashd_0000000124

Abstract

Anksiyete korku ve endişe gibi emosyonları içeren bir durumdur. Anksiyetenin altında yatan mekanizmayı anlamak, yeni tedavi seçenekleri oluşturmak amacıyla hayvan anksiyete testleri kullanılmaktadır. Bu derlemede şartsız anksiyete testi olarak sıklıkla kullanılan açık alan testi, yükseltilmiş artı labirent testi ve aydınlık karanlık kutusu testi incelenmiştir

Keywords

Açık alan testi Anksiyete Aydınlık karanlık kutusu Yükseltilmiş artı labirent Şartsız anksiyete testleri

References

  • Andreatini R, Bacellar LF Braz J. The relationship between anxiety and depression in animal models: a study using the forced swimming test and elevated plus-maze. Med Biol Res. 1999; 32(9):1121-6.
  • Arantes R, Tejada J, Bosco GG, Morato S, Roque AC. Mathematical methods to model rodent behavior in the elevated plus-maze. J Neurosci Methods. 2013; 220(2):141-8.
  • Bagewadı HG, Ak AK, Shıvaramegowda RM. An Experimental Study to Evaluate the Effect of Memantine in Animal Models Anxiety in Swiss Albino Mice. J Clin Diagn Res. 2015; 9(8):1-5.
  • Belzung C, Misslin R, Vogel E, Dodd RH, Chapouthier G. Anxiogenic effects of methyl-beta- carboline-3-carboxylate in a light/dark choice situation. Pharmacol Biochem Behav. 1987; 28(1): 29
  • Bourin M, Petit-Demoulière B, Dhonnchadha BN, Hascoet M (2007) . Animal models of anxiety in mice. Fundam Clin Pharmacol. 2007; 21(6): 567-74.
  • Cagni P, Barros M. Cannabinoid type 1 receptor ligands WIN 55,212-2 and AM 251 alter anxiety-like behaviors of marmoset monkeys in an open-field test. Behav Brain Res. 2013; 240: 91-94
  • Candland DK, Nagy ZM. The open field: some comperative data. Annals New York Academy of Sciences. 1969; 159: 831-851.
  • Carobrez AP, Bertoglio LJ. Ethological and temporal analyses of anxiety-like behavior: The elevated plus-maze model 20 years on. Neuroscience and Biobehavioral Reviews. 2005; 29: 1193–1205.
  • Crawley J, Goodwin FK. Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav. 1980; 13(2):167-170.
  • Ehrlıch A, Burns N. Exploratory behaviour of the black footed ferret. Canadian Journal of psychology. ; 12: 235-241. Fıset C, Rıoux FM, Surette ME, Fıset S. Prenatal Iron Deficiency in Guinea Pigs Increases Locomotor Activity but Does Not Influence Learning and Memory. PLoS One. 2015; 10(7): 0133168.
  • Hall CS. Emotional behavior in rat: Defaction and urination as measure of individual diffirences in emotionality. Journal of comparative Psychology. 1934; 18: 385-403.
  • Handley SL, Mıthanı S. Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ’fear’-motivated behaviour. Naunyn Schmiedebergs Arch. Pharmacol. 1984; 327:1-5.
  • Imaizumi M, Miyazaki S, Onodera K. Effects of xanthine derivatives in a light/dark test in mice and contribution of adenosine receptors. Methods Find. Exp. Clin. Pharmacol. 1994; 16: 639–644.
  • Kalueff AV, Tuohımaa P. Experimental modeling of anxiety and depression. Acta Neurobiol Exp. 2004; : 439-448.
  • Korte SM, De Boer SF. A robust animal model of state anxiety: fear-potentiated behaviour in the elevated plus-maze. Eur J Pharmacol. 2003; 463(1-3): 163-175.
  • Kumar V, Bhat ZA, Kumar D. Animal models of anxiety: a comprehensive review. 2013; 68(2): 175
  • Martinek Z, Lat J. Long term stability of individual differences in exploratory behavior and rate of habituation in dogs. Physiol Bohemoslov. 1969; 18: 217–225.
  • Meıjer E, Van Nes A, Back W, Van Der Staay FJ. Clinical effects of buprenorphine on open field behaviour and gait symmetry in healthy and lame weaned piglets. Vet J. 2015; 206(3): 303.
  • Montgomery KC. The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol. 1955; 48(4): 254-260.
  • Mushtaq MY, Marçal RM, Champagne DL, Van Der Kooy F, Verpoorte R, ChoI YH. Effect of acute stresses on zebra fish (Danio rerio) metabolome measured by NMR-based metabolomics. Planta Med. ; 80(14): 1227-1233.
  • Oldham J, Morlock H. The effects of open field size on activity in the mongolian gerbil. Psycohonomic Science. 1970; 20: 290.
  • Pedernera-Romano C, Ruız De La Torre JL, Badıella L, Manteca X. Effect of perphenazine enanthate on open-field test behaviour and stress-induced hyperthermia in domestic sheep. Pharmacol Biochem Behav. 2010; 94(3): 329-332.
  • Pellow S, Chopin P, File SE, Briley M. Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci Methods. 1985; 14: 149-167.
  • Porsolt RD, Le Pıchon M, Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature. 1977; , 266(5604): 730-732.
  • Porsolt RD, Anton G, Blavet N, Jalfre M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol. 1978a; 47(4): 379-391.
  • Porsolt RD, Bertın A, Jalfre M. “Behavioural despair” in rats and mice: strain differences and the effects of imipramine. Eur J Pharmacol. 1978b; 51: 291-294.
  • Prut I, Belzung C. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. European Journal of Pharmacology. 2003; 463: 3-33.
  • Sayapina NV, Batalova TA, Chaıka VV et al. Multi-walled carbon nanotubes increase anxiety levels in rats and reduce exploratory activity in the open field test. Dokl Biol Sci. 2015; 464(1): 223-225.
  • Soubrie P. Open field chez le rat: interrelations entre locomotion exploration et emotivite. J. Pharmacol. ; 2: 457-472. Stahl SM (2015). Stahl’ın Temel Psikofarmakolojisi, Sinirbilimsel Temeli ve Pratik Uygulaması. Ed:
  • Prof.Dr. Tunç Alkın. S. : 388-420. Wall PM, Messier C. Methodological and conceptual issues in the use of the elevated plus-maze as a psychological measurement instrument of animal anxiety-like behavior. Neurosci Biobehav Rev. 2001; (3): 275-286.
  • Walsh RN, Cummimis RA. The open-field test A critical review. Psychological Bulletin. 1976; 83: 482
  • Zimbardo PF, Montgomery KC. Effects of free environment rearing upon exploratory behavior. Psychological Repoils. 1957; 3: 589-594.
There are 32 citations in total.

Details

Other ID JA58PY24CH
Journal Section Research Article
Authors

Hasan Çalışkan This is me

Fırat Akat This is me

Nezahat Zaloğlu This is me

Publication Date May 1, 2017
Submission Date May 1, 2017
Published in Issue Year 2017 Volume: 16 Issue: 1

Cite

APA Çalışkan, H., Akat, F., & Zaloğlu, N. (2017). Şartsız Hayvan Anksiyete Testleri. Ankara Sağlık Hizmetleri Dergisi, 16(1), 35-40. https://doi.org/10.1501/Ashd_0000000124
AMA Çalışkan H, Akat F, Zaloğlu N. Şartsız Hayvan Anksiyete Testleri. ASHD. May 2017;16(1):35-40. doi:10.1501/Ashd_0000000124
Chicago Çalışkan, Hasan, Fırat Akat, and Nezahat Zaloğlu. “Şartsız Hayvan Anksiyete Testleri”. Ankara Sağlık Hizmetleri Dergisi 16, no. 1 (May 2017): 35-40. https://doi.org/10.1501/Ashd_0000000124.
EndNote Çalışkan H, Akat F, Zaloğlu N (May 1, 2017) Şartsız Hayvan Anksiyete Testleri. Ankara Sağlık Hizmetleri Dergisi 16 1 35–40.
IEEE H. Çalışkan, F. Akat, and N. Zaloğlu, “Şartsız Hayvan Anksiyete Testleri”, ASHD, vol. 16, no. 1, pp. 35–40, 2017, doi: 10.1501/Ashd_0000000124.
ISNAD Çalışkan, Hasan et al. “Şartsız Hayvan Anksiyete Testleri”. Ankara Sağlık Hizmetleri Dergisi 16/1 (May 2017), 35-40. https://doi.org/10.1501/Ashd_0000000124.
JAMA Çalışkan H, Akat F, Zaloğlu N. Şartsız Hayvan Anksiyete Testleri. ASHD. 2017;16:35–40.
MLA Çalışkan, Hasan et al. “Şartsız Hayvan Anksiyete Testleri”. Ankara Sağlık Hizmetleri Dergisi, vol. 16, no. 1, 2017, pp. 35-40, doi:10.1501/Ashd_0000000124.
Vancouver Çalışkan H, Akat F, Zaloğlu N. Şartsız Hayvan Anksiyete Testleri. ASHD. 2017;16(1):35-40.