Akromegali Hastalarında Kolon Polip İnsidansı ve Poliplerin Klinik Özelliklerle İlişkisi
Öz
ÖZET
Akromegali Hastalarında Kolon Polip İnsidansı ve Poliplerin Klinik Özelliklerle İlişkisi
Amaç: Akromegalilerde kolon polip insidansının saptanması ve kolon polipi olan ve olmayan hastaların demografik özelliklerinin, endokrinolojik ve klinik parametrelerinin karşılaştırılması amaçlandı.
Materyal ve Metot: KTÜ Tıp Fakültesinde, 70 Akromegali hastası, retrospektif olarak kolonoskopik bulgularına göre incelendi.
Bulgular: 70 Akromegali olgusunun 18’inde (%25,7) kolonda polip saptandı.
Kolon polipleri ile sigara, hemoglobin, MCV ve bazal IGF-1 düzeyi arasında anlamlı bir ilişki saptandı. Bazal IGF-1 düzeyi, kolon polipi olan Akromegali hastalarında daha düşük bulundu (p= 0.045).
Sonuç: Akromegali hastalarında kolon polip insidansı %25,7 olarak saptandı, normal popülasyona göre artmış olduğu gözlendi.
Anahtar Sözcükler: Akromegali; Kolon Polip; IGF-1
SUMMARY
Colonic Polyp İncidence in Patients with Acromegaly and Its Relationship with Clinical
Characterictics
Aim: It was aimed to determine the incidance of colon polyps in Acromegaly and to
compare the demographic characteristics, endocrinological and clinical parameters of patients
with and without colon polyps.
Material and Method: 70 patients with Acromegaly at KTU Faculty of Medicine were evaluated retrospectively according to their colonoscopic findings.
Results: Colon polyps were detected in 18 (25.7%) of 70 Acromegaly cases. There was a significant correlation was found between colon polyps and smoking, hemoglobin, MCV and basal IGF-1 levels. Basal IGF-1 levels were found to be low in patients with colon polyps (p=0.045).
Conclusion: The incidance of polyps in patients with Acromegaly was found to be 25,7%, it was observed to be increased compared to the normal population.
Key Words: Acromegaly; Colon Polyp; IGF-1
Anahtar Kelimeler
References
- . Sobin, L.H., The histopathology of bleeding from polyps and carcinomas of the large intestine. Cancer, 1985. 55(3): p. 577-81.
Details
Primary Language
Turkish
Subjects
Clinical Sciences , Internal Diseases
Journal Section
Clinical Research
Publication Date
January 26, 2024
Submission Date
March 31, 2023
Acceptance Date
August 26, 2023
Published in Issue
Year 2024 Volume: 4 Number: 3