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Buprenorfin/Naloksan Tek Dozuna Bağlı Yan Etkiler: Olgu Bildirimi

Year 2021, Volume: 2 Issue: 3, 27 - 29, 31.12.2021

Abstract

Opioid bağımlılığı tüm dünyada pek çok insanı etkileyen kronik, tekrarlayıcı bir durumdur ve yaygınlığı gittikçe artmaktadır. Opioid yoksunluğundan arındırma ve opioid yerine koyma tedavilerinde buprenorfin/nalokson kombinasyonu içeren dilaltı tabletlerin kullanılmaya başlanmıştır. Buprenorfin bir kısmi opioid agonistidir. Bu nedenle normal kişilerde kullanımında başta opioid benzeri etkiler gösterebilir.
Olgu: Otuz yedi yaşında erkek hasta halsizlik, titreme, huzursuzluk ve yerinde duramama şikayetleri ile acil servise başvurdu. Özgeçmişinde herhangi bir hastalığı olmayan hastanın yaklaşık 2 saat önce baş ağrısı olmuş. Kendisine yanındaki arkadaşı tarafından bir ağrı kesici olduğunu bildiği bir ilaç verilmiş. İlacı aldıktan yaklaşık yarım saat sonra şikayetleri başlamış. Yapılan araştırmada alınan ilacın Buprenorfin/Naloksan kombinasyonu olan opioid bağımlılık tedavisinde kullanılan ilaç olduğu anlaşıldı. Hastaya sıvı tedavisi başlandı. Monitörize edildi. 24 saat takip için hasta servise yatırıldı.
Sonuç: Morfin, Eroin gibi uyuşturucu maddelerin kullanımının günümüzde artmasıdır. Bu yazıdaki amacımız maddelerin ve bağımlılık tedavisinde kullanılan ilaçların ilk doz alımında karşılaşacağımız durumları sorgulamak ve acil serviste yaklaşımı üzerinde durmaktır.
Abstract
Opioid addiction affects many people all over the world chronic, relapsing condition and prevalence is increasing. Detoxification and opioid substitution treatment in opioid withdrawal from Buprenorfin/Naloksan combination sublingual tablets have been used in that contains. Buprenorphine, is an opioid partial agonist. Therefore, in normal subjects the use of opioid –like effects may show.
Case Report:
Thirty-seven-year-old male patient with fatigue, tremors, irritability and restlessness was admitted to the emergency room with complaints of. He didn’t have previously known a disease of patient. Two hours before the headache started.Know that was given a drug by his friend next to him is a pain reliever. After about half an hour after taking the medication, the complaints started. We investigated.After we understood that it is a drug that Buprenerfin/Naloksan combination. The fluid therapy was started to patient. The patient was admitted to the service to monitor for 24 hours.
Result: Our aim to present this case today is an increase in the use of drugs such as morphine, heroin.The first dose of drugs used in the treatment of addicition to the these substances and situations that we encounter in the emergency room on the approach to stop and inquire about it.

References

  • 1. McLellan AT, Lewis DC, O’Brien CP, et al.: Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. JAMA 2000;284:1689-1695
  • 2. Veilleux JC, Colvin PJ, Anderson J, et al.: A review of opioid dependence treatment: pharmacological and psychosocial interventions to treat opioid addiction. Clin Psychol Rev 2010;30:155-166
  • 3. Gowing, L. R., & Ali, R. L. (. Opioid bağımlılığı tedavisinde detoksifikasyonun yeri. Current Opinion in Psychiatry 2006;2(3), 138-143
  • 4. Cavid Guliyev Predictive Factors for Treatment Success in the Early Period of Buprenorphine/Naloxone Maintenance Treatment for Opiate AddictionThe Turkish Journal on Addictions 2015; 2(1) : 5-27
  • 5. Tellioglu, T. Buprenorphine: A new alternative in the treatment of opioid addiction. Klinik Psikofarmakoloji Bülteni 2010, 20(3), 263-265
  • 6. Sidarth Wakhlu. Buprenorphine: A review.Journol of Opioid Management. Vol 5, No 1 (2009)
  • 7. Fiellin DA, O’Connor PG: Clinical practice. Office-based treatment of opioid-dependent patients. N Engl J Med 2002;347:817-823
  • 8. Ling W; Wesson DR; Charuvastra C; Klett CJ A controlled trial comparing buprenorphine and methadone maintenance in opioid dependence. Arch Gen Psychiatry 1996;53:401-7.
  • 9. Strain EC; Stitzer ML; Liebson IA; Bigelow GE Comparison of buprenorphine and methadone in the treatment of opioid dependence. Am J Psychiatry 1994; 151:1025-30
Year 2021, Volume: 2 Issue: 3, 27 - 29, 31.12.2021

Abstract

References

  • 1. McLellan AT, Lewis DC, O’Brien CP, et al.: Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. JAMA 2000;284:1689-1695
  • 2. Veilleux JC, Colvin PJ, Anderson J, et al.: A review of opioid dependence treatment: pharmacological and psychosocial interventions to treat opioid addiction. Clin Psychol Rev 2010;30:155-166
  • 3. Gowing, L. R., & Ali, R. L. (. Opioid bağımlılığı tedavisinde detoksifikasyonun yeri. Current Opinion in Psychiatry 2006;2(3), 138-143
  • 4. Cavid Guliyev Predictive Factors for Treatment Success in the Early Period of Buprenorphine/Naloxone Maintenance Treatment for Opiate AddictionThe Turkish Journal on Addictions 2015; 2(1) : 5-27
  • 5. Tellioglu, T. Buprenorphine: A new alternative in the treatment of opioid addiction. Klinik Psikofarmakoloji Bülteni 2010, 20(3), 263-265
  • 6. Sidarth Wakhlu. Buprenorphine: A review.Journol of Opioid Management. Vol 5, No 1 (2009)
  • 7. Fiellin DA, O’Connor PG: Clinical practice. Office-based treatment of opioid-dependent patients. N Engl J Med 2002;347:817-823
  • 8. Ling W; Wesson DR; Charuvastra C; Klett CJ A controlled trial comparing buprenorphine and methadone maintenance in opioid dependence. Arch Gen Psychiatry 1996;53:401-7.
  • 9. Strain EC; Stitzer ML; Liebson IA; Bigelow GE Comparison of buprenorphine and methadone in the treatment of opioid dependence. Am J Psychiatry 1994; 151:1025-30
There are 9 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Olgu Sunumu
Authors

Keziban Uçar Karabulut 0000-0001-9188-0266

Publication Date December 31, 2021
Submission Date January 13, 2021
Acceptance Date April 14, 2021
Published in Issue Year 2021 Volume: 2 Issue: 3

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