REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI

Gökhan Özkan; Ali Toptaş

doi:10.17567/ataunidfd.290567

REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI

Abstract

Rekürrent aftöz stomatit, yaygın, ağrılı, etiyolojisi kesin olarak bilinmeyen ve tekrar eden oral ülserlerden oluşur. Oral ülserler farklı sayı ve büyüklükte ortaya çıkabilir. Klinik olarak; minör, majör ve herpetiform olmak üzere üç alt grup altında toplanır. Bu ülserler, tek başına ortaya çıkabildiği gibi, bazı sistemik hastalıklarla beraber de görülebilir. Tedavisi genellikle semptomatiktir. Tedavisinde analjezikler, antiseptikler, antibiyotikler, kortikosteroidler ve lazer gibi ilaç ve yöntemler önerilir. Bu derlemede, rekürrent aftöz stomatitin olası etiyolojik faktörleri, klinik bulguları ve güncel tedavi alternatifleri tanımlanmaktadır.

Anahtar Kelimeler: Rekürrent aftöz stomatit, oral ülserler, tedavi

RECURRENT APHTHOUS STOMATITIS: RECENT THERAPEUTIC APPROACHES

ABSTRACT

Recurrent aphthous stomatitis compose of widespread, painful and recurring oral ulcers of unknown etiology. Oral ulcers may occur in different number and size. Clinically, it is divided into three subgroups as minor, major and herpetiformis. These ulcers can occur alone or can be seen with some systemic diseases. The treatment is usually symptomatic. Analgesics, antiseptics, antibiotics, corticosteroids and laser theraphy are recommended in the treatment. In this review, the possible etiological factors, clinical presentation and the current treatment alternatives of recurrent apthous stomatitis is described.

Key words: Recurrent aphthous stomatitis, oral ulcers, treatment

Keywords

Rekürrent aftöz stomatit,oral ülserler

References

Çağlayan F, Yılmaz AB. Rekürrent aftöz stomatitis. Atatürk Üniv. Diş Hek. Fak. Derg 2009; 19: 47-54.
2. Chavan M, Jain H, Diwan N, Khedkar S, Shete A, Durkar S. Recurrent aphthous stomatitis: a review. J Oral Pathol Med 2012; 41: 577-83.
3. Riera Matute G, Riera Alonso E. [Recurrent aphthous stomatitis in Rheumatology]. Reumatol Clin 2011; 7: 323-8.
4. Ozbayrak S. Ağız Hastalıkları Atlası. 1.bs. Esenyurt-Istanbul; Doğan Ofset: 2003. s. 18-23.
5. Slebioda Z, Szponar E, Kowalska A. Recurrent aphthous stomatitis: genetic aspects of etiology. Postepy Dermatol Alergol 2013; 30: 96-102.
6. Slebioda Z, Szponar E, Kowalska A. Etiopathogenesis of recurrent aphthous stomatitis and the role of immunologic aspects: literature review. Arch Immunol Ther Exp (Warsz) 2014; 62: 205-15.
7. Gallo Cde B, Mimura MA, Sugaya NN. Psychological stress and recurrent aphthous stomatitis. Clinics (Sao Paulo) 2009; 64: 645-8.
8. Wardhana, Datau EA. Recurrent aphthous stomatitis caused by food allergy. Acta Med Indones 2010; 42: 236-40.

9. Preeti L, Magesh K, Rajkumar K, Karthik R. Recurrent aphthous stomatitis. J Oral Maxillofac Pathol 2011; 15: 252-6
19. Yakar T, Serin E, Coşar AM, Arslan Taş D, Ataç FB. The relationship of recurrent aphthous stomatitis and Helicobacter pylori, cytokine gene polymorphism and cobalamin. Turk J Gastroenterol 2015; 26: 304-8.
20. Liang MW, Neoh CY. Oral aphthosis: management gaps and recent advances. Ann Acad Med Singapore 2012; 41: 463-70.
21. Kozlak ST, Walsh SJ, Lalla RV. Reduced dietary intake of vitamin B12 and folate in patients with recurrent aphthous stomatitis. J Oral Pathol Med 2010; 39: 420-3.
22. Ozler GS. Zinc deficiency in patients with recurrent aphthous stomatitis: a pilot study. J Laryngol Otol 2014; 128: 531-3.
23. Patil S, Reddy SN, Maheshwari S, Khandelwal S, Shruthi D, Doni B. Prevalence of recurrent aphthous ulceration in the Indian Population. J Clin Exp Dent 2014; 6: e36-40.
Rhee SH, Kim YB, Lee ES. Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptoms. J Korean Med Sci 2005; 20: 971-6.
25. Seoudi N, Bergmeier LA, Drobniewski F, Paster B, Fortune F. The oral mucosal and salivary microbial community of Behcet's syndrome and recurrent aphthous stomatitis. J Oral Microbiol 2015; 7: 27150.
26. Shakeri R, Zamani F, Sotoudehmanesh R, Amiri A, Mohamadnejad M, Davatchi F, Karakani AM, Malekzadeh R, Shahram F. Gluten sensitivity enteropathy in patients with recurrent aphthous stomatitis. BMC Gastroenterol 2009; 9: 44.
27. Scully C, Hodgson T. Recurrent oral ulceration: aphthous-like ulcers in periodic syndromes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106: 845-52.
28. Albrektson M, Hedstrom L, Bergh H. Recurrent aphthous stomatitis and pain management with low-level laser therapy: a randomized controlled trial. Oral Surg Oral Med Oral Pathol Oral Radiol 2014; 117: 590-4.
29. Lalla RV, Choquette LE, Feinn RS, Zawistowski H, Latortue MC, Kelly ET, Baccaglini L. Multivitamin therapy for recurrent aphthous stomatitis: a randomized, double-masked, placebo-controlled trial. J Am Dent Assoc 2012; 143: 370-6.
. Borhan-Mojabi K, Mirmiran F, Nassiri-Asl M, Nazeman P, Jahanihashemi H. Therapeutic Effects of "Ibuprofen, Diphenhydramine and Aluminium MgS" on Recurrent Aphthous Stomatitis: A Randomized Controlled Trial. J Dent (Tehran) 2014; 11: 167-71.
31. Deshmukh RA, Bagewadi AS. Comparison of effectiveness of curcumin with triamcinolone acetonide in the gel form in treatment of minor recurrent aphthous stomatitis: A randomized clinical trial. Int J Pharm Investig 2014; 4: 138-41.
32. Sharda N, Shashikanth MC, Kant P, Jain M. Levamisole and low-dose prednisolone in the treatment of reccurent aphthous stomatitis. J Oral Pathol Med 2014; 43: 309-16.
33. Darshan DD, Kumar CN, Kumar AD, Manikantan NS, Balakrishnan D, Uthkal MP. Clinical study to know the efficacy of Amlexanox 5% with other topical Antiseptic, Analgesic and Anesthetic agents in treating minor RAS. J Int Oral Health 2014; 6: 5-11.
34. Pakfetrat A, Mansourian A, Momen-Heravi F, Delavarian Z, Momen-Beitollahi J, Khalilzadeh O, Basir-Shabestari S. Comparison of colchicine versus prednisolone in recurrent aphthous stomatitis: A double-blind randomized clinical trial. Clin Invest Med 2010; 33: E189-95.
35. Sharquie KE, Najim RA, Al-Hayani RK, Al-Nuaimy AA, Maroof DM. The therapeutic and prophylactic role of oral zinc sulfate in management of recurrent aphthous stomatitis (ras) in comparison with dapsone. Saudi Med J 2008; 29: 734-8.
36. Sattayut S, Trivibulwanich J, Pipithirunkarn N, Danvirutai N. A clinical efficacy of using CO2 laser irradiating to transparent gel on aphthous stomatitis patients. Laser Ther 2013; 22: 283-9.
37. Tezel A, Kara C, Balkaya V, Orbak R. An evaluation of different treatments for recurrent aphthous stomatitis and patient perceptions: Nd:YAG laser versus medication. Photomed Laser Surg 2009; 27: 101-6.

Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Gökhan Özkan

Ali Toptaş This is me

Publication Date

November 24, 2016

Submission Date

January 21, 2016

Acceptance Date

March 3, 2016

Published in Issue

Year 2016

DOI

https://doi.org/10.17567/ataunidfd.290567

IZ

https://izlik.org/JA69SU83TT

Cite

RIS / Bibtex

APA

Özkan, G., & Toptaş, A. (2016). REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, 60-64. https://doi.org/10.17567/ataunidfd.290567

AMA

1.Özkan G, Toptaş A. REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. Published online November 1, 2016:60-64. doi:10.17567/ataunidfd.290567

Chicago

Özkan, Gökhan, and Ali Toptaş. 2016. “REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, November 1, 60-64. https://doi.org/10.17567/ataunidfd.290567.

EndNote

Özkan G, Toptaş A (November 1, 2016) REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 60–64.

IEEE

[1]G. Özkan and A. Toptaş, “REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI”, Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, pp. 60–64, Nov. 2016, doi: 10.17567/ataunidfd.290567.

ISNAD

Özkan, Gökhan - Toptaş, Ali. “REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. November 1, 2016. 60-64. https://doi.org/10.17567/ataunidfd.290567.

JAMA

1.Özkan G, Toptaş A. REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2016;:60–64.

MLA

Özkan, Gökhan, and Ali Toptaş. “REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Nov. 2016, pp. 60-64, doi:10.17567/ataunidfd.290567.

Vancouver

1.Gökhan Özkan, Ali Toptaş. REKÜRRENT AFTÖZ STOMATİT: GÜNCEL TEDAVİ YAKLAŞIMLARI. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2016 Nov. 1;60-4. doi:10.17567/ataunidfd.290567