Casein Phosphopeptide- Amorphous Calcium Phosphate in Dentistry: A Literature Review

Abstract

Casein is a phosphoprotein in bovine milk and accounts for almost 80 percent of its total protein. Casein fosfopeptit (CPP) is produced as a result of decomposition of casein with trypsin enzyme using a selective deposition method. CPP can remarkably stabilize calcium phosphate in a state-forming CPPamorphous calcium phosphate (ACP) complex. CPPACP is located in topical gels, sugar-free chewing gum and mint dragees at the present day. In this paper, the effectiveness of CPP-ACP and usage in dentistry are presented with a wide review of the literature.

Keywords

• CPP-ACP, dentistry

Diş Hekimliğinde Kazein Fosfopeptit Amorf Kalsiyum Fosfat: Bir Literatür Derlemesi

Abstract

Kazein, süt proteinlerinin yaklaşık %80’ini oluşturan bir fosfoproteindir. Kazein fosfopeptit ise (CPP), seçici çökelme yöntemi kullanarak kazeinin tripsin enzimi ile parçalanması sonucunda elde edilir. CPP, kalsiyum fosfatı CPP-amorf kalsiyum fosfat (ACP) kompleksi şeklinde stabilize edebilir. CPP-ACP, günümüzde topikal jeller, şekersiz sakızlar ve naneli drajeler içinde bulunmaktadır. Bu yazıda CPP-ACP’nin etkinliği ve diş hekimliğinde kullanım alanları geniş bir literatür derlemesi ile sunulmuştur.

Keywords

• CPP-ACP, diş hekimliği

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44. Ordu Üniversitesi Diş Hekimliği Fakültesi Pedodonti Anabilim Dalı 52200 Ordu Telefon: [phone] e-mail: [e-mail]