SQUAMOUS CELL CARCINOMA ARRISING FROM ORAL LICHEN PLANUS: A CASE REPORT

Abstract

Lichenoid reactions represent a family of lesions with different etiologic factors and common clinical and histologic appearance. Lichen planus is a relatively common chronic mucocutaneous lichenoid lesion and the most important complication is malignant transformation. One of the malignant transformation is squamous cell carcinoma. Squamous cell carcinoma is the most common malignancy affecting the oral cavity. The aim of this case report is to present clinical, radiological and histopathological features of squamous cell carcinoma arising from oral lichen planus in a 76-year-old man

Keywords

• lichen planus, oral cancer, squamous cell carcinoma

ORAL LİKEN PLANUSTAN GELİŞEN SKUAMÖZ HÜCRELİ KARSİNOM: VAKA RAPORU

Abstract

Likenoid reaksiyonlar, farklı etiyolojik faktörlere bağlı olarak görülen, ortak klinik ve histolojik özelliklere sahip lezyonlardır. Liken planuslar, oral bölgede nispeten sık görülen mukokütanöz likenoid lezyonlardan biridir ve en önemli komplikasyonları malign transformasyon göstermeleridir. Malign transformasyonlarından biri de skuamöz hücreli karsinomlardır. Skuamöz hücreli karsinom, oral kaviteyi etkileyen en sık görülen malignitedir. Bu vaka raporunun amacı, 76 yaşında erkek hastada oral liken planustan gelişen skuamöz hücreli karsinomun klinik, radyolojik ve histopatolojik özelliklerini sunmaktır.

Keywords

• liken planus, oral kanser, skuamöz hücreli karsinom

References

1. Greenberg MS GM, Ship JA. Burket’s Oral Medicine. 11th ed. BC Decker Inc: Hamilton; 2008.
2. Mignogna MD, Lo Muzio L, Lo Russo L, Fedele S, Ruoppo E, Bucci E. Clinical guidelines in early detection of oral squamous cell carcinoma arising in oral lichen planus: a 5-year experience. Oral oncology 2001;37:262-7.
3. Mattsson U, Jontell M, Holmstrup P. Oral lichen planus and malignant transformation: is a recall of patients justified? Critical reviews in oral biology and medicine : an official publication of the American 2002;13:390-6. of Oral Biologists
4. Johnson NW, Jayasekara P, Amarasinghe AA. Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology. Periodontology 2000 2011;57:19-37.
5. Lubek JE, Clayman L. An update on squamous carcinoma of the oral cavity, oropharynx, and maxillary sinus. Oral and maxillofacial surgery clinics of North America 2012;24:307-16, x.
6. Eisenberg E. Clinicopathologic patterns of oral lichenoid lesions. Oral Maxillofac Surg Clin North Am 1994;6:445.
7. Cortés-Ramírez D-A,
8. Gainza-Cirauqui M-L,

9. Echebarria-Goikouria M-A, Aguirre-Urizar JM. Oral
10. lichenoid disease as a premalignant condition: the
11. controversies and the unknown. Med Oral Patol
12. Oral Cir Bucal 2009;14:E118-E22.
13. Sharma P, Saxena S, Aggarwal P. Trends in the epidemiology of oral squamous cell carcinoma in Western UP: an institutional study. Indian journal of dental research : official publication of Indian Society for Dental Research 2010;21:316-9.
14. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA: a cancer journal for clinicians 2010;60:277-300.
15. Gil Z, Carlson DL, Boyle JO, Kraus DH, Shah JP, Shaha AR, et al. Lymph node density is a significant predictor of outcome in patients with oral cancer. Cancer 2009;115:5700-10.
16. Seoane J, Varela-Centelles PI, Walsh TF, Lopez- Cedrun JL, Vazquez I. Gingival squamous cell carcinoma: diagnostic delay or rapid invasion? Journal of periodontology 2006;77:1229-33.
17. Bulut E, Yılmaz F, Bekçioğlu B, Günhan Ö. Posterior Alveoler Krette Dişeti Yerleşimli Skuamöz Hücreli Karsinoma: Olgu Sunumu. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 2013;23: 239-43
18. Hong SX, Cha IH, Lee EW, Kim J. Mandibular invasion of lower gingival carcinoma in the molar region: its clinical implications on the surgical management. International journal of oral and maxillofacial surgery 2001;30:130-8.
19. Çakur B, Sümbüllü MA, Durna D, Çanakçı CF. Dento-alveolar kırık teşhisinde dental volümetrik bilgisayarlı tomografi. Atatürk Üniv Diş Hek Fak Derg 2012;22:57-60.
20. Sobin LH GM, Wittekind C. TNM classification of malignant tumours. Oxford: Wiley & Sons 2009.
21. Patel SG, Lydiatt WM. Staging of head and neck cancers: is it time to change the balance between the ideal and the practical? Journal of surgical oncology 2008;97:653-7.
22. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. Cancer statistics, 2008. CA: a cancer journal for clinicians 2008;58:71-96.
23. Sun ZJ, Zhang L, Hall B, Bian Y, Gutkind JS, Kulkarni chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model. Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18:5304-13. and
24. Licitra L, Locati LD, Bossi P. Optimizing approaches to head and neck cancer. Metastatic head and neck cancer: new options. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19 Suppl 7:vii200-3.
25. Massano J, Regateiro FS, Januario G, Ferreira A. Oral squamous cell carcinoma: review of prognostic and predictive factors. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2006;102:67-76.