THE USE OF OZONE THERAPY IN PERIODONTOLOGY

Abstract

one have been used in medical field for a long time due to its benefits against bacteria, fungi, viruses and bleeding control. The information about ozone therapy in dentistry is limited. Immunstimulative, increasing the local oxygen supply, supporting hemostasis and antimicrobial effects of ozone recently raise the use of ozone therapy in dentistry. It have been thought that using ozone with mechanical treatment in initial periodontal therapy and in surgical periodontal therapy may contribute clinical outcomes. In this review with properties of ozone, in dentisry and especially in periodontology it has been evaluated along with past studies

Keywords

• Ozone
• periodontology
• periodontal pathogen

OZON TEDAVİSİNİN PERİODONTOLOJİDE KULLANIMI

Abstract

Ozon, bakteri, mantar ve virüsler üzerindeki etkisi ve kanama kontrolünde sağladığı yarar nedeniyle tıp alanında uzun süredir kullanılmaktadır. Diş hekimli- ğinde ise ozon tedavisinin uygulanması ile ilgili bilgiler sınırlıdır. İmmünstimülatif, lokal oksijen desteğini arttıran, hemostazı destekleyen ve antimikrobiyal özelliklerinden dolayı diş hekimliğinde kullanımı son yıllarda gündeme gelmiştir. Periodontal başlangıç tedavisinde mekanik tedavi ile birlikte ve cerrahi işlemlerde uygulanmasının klinik sonuçlara ek bir yarar sağlayabileceği düşünülmektedir. Bu derlemede ozo- nun sahip olduğu özelliklerle birlikte diş hekimliğinde ve özellikle periodontolojide kullanımı, daha önce yapılan çalışmalarla birlikte  değerlendirilmiştir.

Keywords

• Ozon
• periodontoloji
• periodontal patojen

References

1. Grootveld M, Baysan A, Siddiqui N, Sim J, Silwood C, Lynch E. History of clinical publications of ozone. In: Lynch E, editor. Ozone: the revolution in dentistry. London: Quintessence Publishing Co; 2004. p. 23-30.
2. Stopka P. Ozon. Progresdent 2003; 6: 8–11.
3. Filippia A. The effect of ozonated water on epithelial wound healing. Douch Dent J 2001; 143: 96–101.
4. Sunnan GV. Ozone in medicine: Overview and future directions. J Adv Med 1988; 1: 159–74.
5. Bocci V. Biological and clinical effects of ozone. Has ozone therapy a future in medicine? Br J Biomed Sci 1999; 56: 270–9.
6. Sameer M, Monica M. Ozone treating dental infections. Ind J Stomatol 2011; 2: 256–9.
7. Azarpazhooh A, Limeback H. The application of ozone in dentistry: a systematic review of literature. J Dent 2008; 36: 104–16.
8. Nagayoshi M, Kitamura C, Fukuizumi T, Nishihara T, Terashita M. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. J Endodontics 2004; 30: 778-81.

9. Nagayoshi M, Fukuizumi T, Kitamura C, Yano J, Terashita M, Nishihara T. Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiology & Immunology 2004; 19: 240-6.
10. Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi T, Morikawa M, Kakinoki Y, Nishihara T. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiology & Immunology 2005; 20: 206-10.
11. Celiberti P, Pazera P, Lussi A. The impact of ozone treatment on enamel physical properties. Am J Dentistry 2006; 19: 67–72.
12. Priyamak AA. Ozone: The Revolution in Dentistry. Copenhagen: Quintessence Publishing; 2004. p. 155–64.
13. Huth KC, Quirling M, Lenzke S, Paschos E, Kamereck K, Brand K, Hickel R, Ilie N. Effectiveness of ozone against periodontal pathogenic microorganisms. Eur J Oral Sci 2011; 119: 204–10.
14. Gupta G ve Mansi B. Ozone therapy in periodontics. J Med Life 2012; 5: 59-67.
15. Baysan A, Whiley RA, Lynch E. Antimicrobial effect of a novel ozone-generating device on microorganisms associated with primary root carious resins in vitro. Caries Res 2000; 34: 498- 501.
16. Seidler V, Linetskiy I, Hubalkova H. Ozone and Its Usage in General Medicine and Dentistry. A Review Article. Prague Medical Report 2008; 109: 5–13.
17. Srikanth A, Sathish M, Sri Harsha AV. Application of ozone in the treatment of periodontal disease. J Pharm Bioallied Sci Jun 2013; 5: 89-94.
18. Matsumura K, Hyon SH, Nakajima N. Surface modiŞcation of polyethylene-co-vinyl alcohol hydroxyapatite immobilization and control of periodontal Biomaterials 2004; 25: 4817–24. cells differentiation.
19. Nogales CG, Ferrari PH, Kantorovich EO. Ozone therapy in medicine and dentistry. J Contemp Dental Pract 2008; 9: 1–9.
20. Baysan A, Lynch E. The use of ozone in dentistry and medicine. Prim Dent Care 2005; 12: 47–52.
21. Nogales CG, Ferrari PA, Kantorovich EO. Ozone Therapy in Medicine and Dentistry. J Contemp Dent Pract 2008; 9: 75–84.
22. Thanomsub B, Anupunpisit V, Chanphetch S, Watcharachaipong T, Poonkhum R, Srisukonth C. Effects of ozone treatment on cell growth and ultrastructural changes in bacteria. J Gen Appl Microbiol 2002; 48: 193–9.
23. Ebensberger U, Pohl Y, Filippi A. PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination. Dent Traumatol 2002; 18: 262–6.
24. Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18- month trial. Gerodontology 2003; 20: 106–14.
25. Hems RS, Gulabivala K, Ng YL, Ready D, Spratt DA. An in vitro evaluation of the ability of ozone to kill a strain of Enterococcus faecalis. Int Endod J 2005; 38: 22–9.
26. Ramzy MI, Gomaa HE, Mostafa MI. Management of aggressive periodontitis using ozonized water. Egypt Med J NRC 2005; 6: 229–45.
27. Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R, Hickel R, Brand K. Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci 2006; 114: 435–40.
28. Müller P, Guggenheim B, Schmidlin PR. Efficacy of gasiform ozone and photodynamic therapy on a multispecies oral biofilm in vitro. Eur J Oral Sci 2007; 115: 77–80.
29. Kshitish D, Laxman VK. The use of ozonated water and 0.2% chlorhexidine in the treatment of periodontitis patients: A clinical and microbiologic study. Indian J Dent Res 2010; 21: 341–8.
30. Dodwad V, Gupta S, Kumar K, Sethi M, Masamatti S. Changing paradigm in pocket therapy-ozone versus conventional irrigation. Int J Public Health Dent 2011; 2: 7–12.
31. Eltaş A, Yavuzer D. Dişeti enflamasyonunun tedavisinde değerlendirilmesi. Bilimleri Dergisi 2012; 2: 29-33. klinik Üniversitesi Sağlık
32. Eltaş A, Yücel SE. Kronik periodontitis tedavisinde gaz ozon kullanımının halitozise etkisi. İnönü Üniversitesi Sağlık Bilimleri Dergisi 2013; 1: 1-4.
33. Montevecchi M, Dorigo A, Cricca M, Checchi L. Comparison of the antibacterial activity of an ozonated oil with chlorhexidine digluconate and povidone-iodine. A disk diffusion test. New Microbiologica 2013; 36: 289-302.
34. Özdemir H, Toker H, Balcı H, Özer H. Effect of ozone therapy on autogenous bone graft healing in calvarial defects: a histologic and histometric study in rats. J Periodont Res 2013; 48: 722–6.
35. Yılmaz S, Algan S, Gürsoy H, Noyan U, Kuru BE, Kadir T. Evaluation of the Clinical and Antimicrobial Effects of the Er:YAG Laser or Topical Gaseous Ozone as Adjuncts to Initial Periodontal Therapy. Photomedicine and Laser Surgery 2013; 31: 293-8.
36. Al Habashneh R, Alsalman W, Khader Y. Ozone as an adjunct to conventional nonsurgical therapy in chronic periodontitis: a randomized controlled clinical trial. J Periodont Res 2014; doi: 10.1111/jre.12177.
37. Sigrun K, İvar SA, Gunnar M. Trend analysis of O3 and CO in the period 1980-1996: A three- dimensional model study. Journal of Geophysical research 2000; 105: 907-33.
38. Skurska A, Pietruska MD, Paniczko-Drezek A. Evaluation of the influence of ozonotherapy on the clinical parameters and MMP levels in patients with chronic and aggressive periodontitis. Advances in Medical Sciences 2010; 55: 297-307.
39. Yeğin Z, Tosun G. Diş Hekimliğinde Ozon ve Kullanım Alanları. Atatürk Üniversitesi Diş Hek. Fak. Dergisi 2013; 23: 116-22.
40. Korkmaz H, Küçükkolbaşı H. Diş Hekimliğinde Ozon Uygulamaları. Atatürk Üniversitesi Diş Hek Fak Derg 2013; 7: 125-34.
41. Karapetian VE, Neugebauer J, Clausnitzer CE, Zoller JE. Comparison of Different Periimplantitis Treatment Methods. [Last accessed on 2013 January 29]. Available from: http://www.helbo.at/ datasheets/poster_karapetian_0304.pdf .