ORAL MALIGNANT MELANOMA: CASE REPORT

Year 2015, Supplement 12, 35 - 39, 24.11.2015

Ümit Ertaş Nesrin Saruhan , Adnan Kılınıç Mustafa Gündodğu

https://doi.org/10.17567/dfd.10468

Abstract

The purpose of this case report is to present clinical and radiological features of malignant melanoma which localized in the hard palate. 65-year-old male patient with prosthes trauma complaint referred to our faculty, ulcerated and bleeding lesion localized in the hard palate was detected by clinical examination. Incisional biopsy was taken from the patient to a definitive diagnosis. Histopathologically, diagnosed, surgical operation was recommended. But malignant

Keywords

Melanoma, hard palate, oral cancer

ORAL MALİGN MELANOM: VAKA RAPORU

Abstract

Bu vaka raporunun amacı, sert damakta lokalize malign melanomun klinik ve radyolojik özelliklerini sunmaktır.

Protez vuruğu şikayetiyle fakültemize başvuran 65 yaşında erkek hastanın yapılan klinik muayenesinde sert damağında lokalize, ülsere, kanamalı lezyon tespit edildi. Kesin tanı koyabilmek için hastadan insizyonel biopsi alındı.

Histopatalojik olarak malign melanom teşhisi koyulan hastaya cerrahi operasyon önerildi. Cerrahi tedaviyi kabul etmeyen hastaya semptomatik tedavi yapıldı.

Malign melanom, oral kavitede nadir olarak görülen kötü prognoza sahip agresif bir tümördür.

Keywords

Melanom, sert damak, oral kanser

References

• Rapini RP. Oral melanoma: diagnosis and treatment. Seminars in cutaneous medicine and surgery 1997;16:320-2.
• Little JW. Melanoma: etiology, treatment, and dental implications. General dentistry 2006;54:61- 66; quiz, 67.
• Mori W. A geo-pathological study on malignant melanoma in Japan. Pathologia et microbiologia 1971;37:169-80.
• Umeda M, Komatsubara H, Shibuya Y, Yokoo S, Komori T. Premalignant melanocytic dysplasia and malignant melanoma of the oral mucosa. Oral oncology 2002;38:714-22.
• Rapini RP, Golitz LE, Greer RO, Jr., Krekorian EA, Poulson T. Primary malignant melanoma of the oral cavity. A review of 177 cases. Cancer 1985;55:1543-51.
• Lengyel E, Gilde K, Remenar E, Esik O. Malignant mucosal melanoma of the head and neck. Pathology oncology research : POR 2003;9:7-12.
• Gorsky M, Epstein JB. Melanoma arising from the mucosal surfaces of the head and neck. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 1998;86:715-9.
• Mendenhall WM, Amdur RJ, Hinerman RW, Werning JW, Villaret DB, Mendenhall NP. Head and neck mucosal melanoma. American journal of clinical oncology 2005;28:626-30.
• Thompson LD, Wieneke JA, Miettinen M. Sinonasal
• nasopharyngeal tract
• clinicopathologic study of 115 cases with a
• proposed staging system. The American journal of
• surgical pathology 2003;27:594-611. a
• Kusukawa J, Suefuji Y, Ryu F, Noguchi R, Iwamoto O, Kameyama T. Dissemination of cancer cells into circulation occurs by incisional biopsy of oral squamous cell carcinoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2000;29:303-7.
• Yii NW, Eisen T, Nicolson M, A'Hern R, Rhys-Evans P, Archer D, Henk JM, Gore ME.. Mucosal malignant melanoma of the head and neck: the Marsden experience over half a century. Clinical oncology 2003;15:199-204.
• Lund V. Malignant melanoma of the nasal cavity and paranasal sinuses. The Journal of laryngology and otology 1982;96:347-55.
• Kingdom TT, Kaplan MJ. Mucosal melanoma of the nasal cavity and paranasal sinuses. Head & neck 1995;17:184-9.
• Lund VJ, Howard DJ, Harding L, Wei WI. Management options and survival in malignant melanoma of the sinonasal mucosa. The Laryngoscope 1999;109:208-11.
• Meleti M, Leemans CR, Mooi WJ, van der Waal I. Oral malignant melanoma: the amsterdam experience. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2007;65:2181-6.
• Wagner M, Morris CG, Werning JW, Mendenhall WM. Mucosal melanoma of the head and neck. American journal of clinical oncology 2008;31:43- 8.
• Nakaya M, Mochiki M, Takeuchi S, Yuge T, Nakao K, Nakamura N, Sugasawa M. Malignant melanoma of nasal cavity: report of 16 Japanese patients. Auris, nasus, larynx 2004;31:233-7.
• Doval D, Rama Rao C, Sabitha K, Vigayakumar M, Misra S, Manie K, Bapsy PP, Kumaraswamy SV. Malignant melanoma of the oral cavity: report of 14 cases from a regional cancer centre. European Journal of Surgical Oncology (EJSO) 1996;22:245- 49.
• Patel SG, Prasad ML, Escrig M, Singh B, Shaha AR, Kraus DH, Boyle JO, Huvos AG, Busam K, Shah JP. Primary mucosal malignant melanoma of the head and neck. Head & neck 2002;24:247-57.
• Howard DJ, Lund VJ, Wei WI. Craniofacial resection for tumors of the nasal cavity and paranasal sinuses: a 25-year experience. Head & neck 2006;28:867-73.
• Calabrese V, Cifola M, Pareschi R, Parma A, Sonzogni A. Primary malignant melanoma of the oral cavity. The Journal of laryngology and otology 1989;103:887-9.
• Prasad ML, Jungbluth AA, Patel SG, Iversen K, Hoshaw-Woodard S, Busam KJ. Expression and significance of cancer testis antigens in primary mucosal melanoma of the head and neck. Head & neck 2004;26:1053-7.
• Iversen K, Robins RE. Mucosal malignant melanomas. American journal of surgery 1980;139:660-4.
• Kazancıoğlu HO,Atay K, Ak G, Tufan F, Doğan Ö, Kalayoğlu-Beşışık S, Bulaşıkçı M. Extranodal Malt Lymphoma Presenting With İsolated Hard Palate Involvement: A Diagnostic Challenge. Atatürk Üniv Diş Hek Fak Derg 2013;23: 69-74.
• Aguas SC, Quarracino MC, Lence AN, Lanfranchi- Tizeira HE. Primary melanoma of the oral cavity: ten cases and review of 177 cases from literature. Medicina oral, patologia oral y cirugia bucal 2009;14:E265-71.
• Lourenco SV, A MS, Sotto MN, Bologna SB, Giacomo TB, Buim ME, Coutinho-Camillo CM, Silva SD, Landman G, Soares FA, Simonsen Nico MM. Primary oral mucosal melanoma: a series of 35 new cases from South America. The American Journal of dermatopathology 2009;31:323-30.
• Lourenco SV, Bologna SB, Colucci F, Neto CF, Montenegro FL, Nico MM. Oral mucosal melanoma of the mandibular gingiva: a case report. Cutis 2010;86:89-93.
• Tucci R, Aburad De Carvalhosa A, Anunciacao G, Daumas Nunes F, Dos Santos Pinto D, Jr. Late diagnosis of a primary oral malignant melanoma: a case report. Minerva stomatologica 2010;59:55-9.
• Gondivkar SM, Indurkar A, Degwekar S, Bhowate R. Primary oral malignant melanoma--a case report and review of the literature. Quintessence international 2009;40:41-6.
• Hashemi Pour MS. Malignant melanoma of the oral cavity: a review of literature. Indian journal of dental research : official publication of Indian Society for Dental Research 2008;19:47-51.
• Hicks MJ, Flaitz CM. Oral mucosal melanoma: epidemiology and pathobiology. Oral oncology 2000;36:152-69.
• Bujas T, Pavic I, Prus A, Marusic Z, Balicevic D. Primary oral malignant melanoma: case report. Acta clinica Croatica 2010;49:55-9.
• Mihajlovic M, Vlajkovic S, Jovanovic P, Stefanovic V. Primary mucosal melanomas: a comprehensive review. International journal of clinical and experimental pathology 2012;5:739-53.
• Moreira RN, Santos CR, Lima NL, Verli FD, Marinho SA. Oral and cutaneous melanoma: similarities and differences. Journal of clinical medicine research 2010;2:155-8.
• Sharma N. Primary oral malignant melanoma: two case reports and review of literature. Case reports in dentistry 2012;2012:975358.