SUBGİNGİVAL PLAK İÇİNDE BAKTERİYEL ETKİLEŞİMLER

Year 2016, Volume: 26 Issue: 3, 542 - 551, 01.12.2016

Zeliha Aytekin , Taner Arabacı

https://doi.org/10.17567/ataunidfd.290456

Abstract

 Periodontitis
polimikrobiyal bir hastalıktır. Araştırma- cılar uzun dönem mikrobiyal
kompleksleri redüksiyo- nist bir yaklaşımla incelemişlerdir. Yani mikroorganiz-
maları mikrobiyal kompleksten ayırıp bireysel olarak inceleyerek oral
mikrobiyal patogenezden sorumlu temel patojenleri belirlemeye çalışmışlardır.
Ancak sonradan farklı mikroorganizmalar arasındaki etkileşi- min bireysel
olarak elde edilemeyecek birçok yeni fizyolojik fonksiyonun oluşmasına neden
olduğunu gör- müşlerdir. Bunun üzerine türler arasındaki etkileşim- ler,
mikrobiyal topluluk polimikrobiyal hastalıklar gibi konulara ilgi artmıştır.
Araştırmaların yönü parçaların tamamını yani bütünü kavramaya yönelmiştir.  Fiziksel ilietişim birbirini takip eden
mikroorganizmalara tutun- ma sahası sağlar, metabolik iletişim lokal çevrenin
patojenlerin büyümesi için uygun hale getirilmesine yardımcı olur; sinyal
molekülleri bakterilerin çevresel değişiklere cevap olarak verdikleri
davranışları düzen- ler. Genetik iletişim antibiyotiklere karşı mikrobiyal di- rencin
oluşmasını sağlar. Türler arası iletişim periodon- tal hastalıkların başlaması
ve ilerlemesinde major rol oynar. Bu derlemenin amacı türler arası etkileşim
senaryolarını derlemektir.

Anahtar
Kelimeler: Subgingival Plak, Bakteriyel Etkileşimler,
Periodontitis

BACTERIAL INTERACTIONS IN SUBGINGIVAL PLAQUE

ABSTRACT 

Periodontitis is a polimicrobial
disease. For a long time, researchers investigated microbial complexes with a
reductionist approach. They extracted microor- ganism from microbial complex
and searched indivi- dually to predefine the key pathogens responsible from
oral microbial pathogenesis. The interaction of different microorganism
observed in many new physiological functions which can not be observed
induvidually. Upon this increased interested in topics such as interspecies
interaction, microbial community and 
polimicrobial diseases. Physical
communication procures the adherence site to the consecutive microorganisms;
metabolic communications cause the suitable local environmental changes for the
growth of pathogens, signaling molecules help bacteria to regulate their
behavior in response to changes in the environment. Genetic communication
ensures the microbial resistance against the antibiotics. Interspecies
communication plays a major role in the initiation and progression of periodontal
disease. The aim of this review is compiled the scenarios interspecies
interaction.

Key Words: Subgingival Plaque,
Bacterial İnteraction, Periodontitis.

Keywords

Subgingival Plak, Bakteriyel Etkileşimler

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