CURRENT APPROACHES FOR TOOTH AGENESIS: A REVIEW

Year 2019, Volume: 29 Issue: 2, 332 - 339, 22.03.2019

Özge Şentürk , Kadriye Görkem Ulu Güzel

https://doi.org/10.17567/ataunidfd.282165

Abstract

ABSTRACT

Hypodontia is defined as the
congenital deficiency of one or more teeth and is one of the most common dental
anomalies in humans. Multifactorial etiology can include environmental factors
as well, since a combination of environmental and genetic factors might
contribute to the occurrence of dental agenesis. Patient with missing teeth;
reduced masticatory ability, inarticulate pronunciation may encounter esthetics
and periodontal problems. Tooth agenesis definition, etiology, genes that cause
tooth agenesis and treatment of tooth agenesis is mentioned in this review.
Nowadays, many genes which play role in tooth development reported to be a
potential candidate gene in tooth agenesis. Functional changes seen in genes
which play role in tooth agenesis are mentioned that there may be a
relationship with the development of cancer and tooth agenesis may be a
significant marker for cancer.

Key Words: Hypodontia, prevalence, neoplasms

Diş Eksikliğinde Güncel Yaklaşımlar: Derleme

ÖZ

           

Hipodonti, bir veya daha fazla dişin konjenital
eksikliği olarak tanımlanır ve insanlarda en sık görülen dental anomalilerden
biridir. Genetik faktörlerin yanısıra çevresel faktörler veya bunların
kombinasyonu diş eksikliklerinin görülmesine sebep olabilmektedir. Eksik
dişlere sahip hastalar; azalmış çiğneme yeteneği, telaffuzun anlaşılamaması,
estetik ve periodontal problemlerle karşılaşabilmektedir. Bu derlemede konjenital diş eksikliği tanımı, etiyolojisi, diş eksikliğine
sebep olan genler ve tedavisinden bahsedilmektedir. Günümüzde, diş
gelişiminde rol alan birçok genin, diş eksikliğinde de potansiyel aday
genler oldukları bildirilmektedir. Diş eksikliğinde rol alan genlerde görülen fonksiyonel değişikliklerin
kanser gelişimiyle bir ilişkisi olabileceğinden ve diş eksikliğinin kanser için
belirleyici bir marker olabileceğinden bahsedilmektedir.

Anahtar
Sözcükler: Hipodonti, prevalans, tümörler

Keywords

Hypodontia, prevalence

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