Review
BibTex RIS Cite

TARÇIN GERÇEKTEN KAN ŞEKERİNİ DÜŞÜRÜYOR MU?

Year 2023, , 42 - 49, 09.03.2023
https://doi.org/10.54270/atljm.2023.30

Abstract

Günümüzde obezitenin artışıyla birlikte insülin direnci ve diyabet yaygın bir halk sağlığı sorunu haline gelmiştir. Bu sebeple ilaç tedavileri, beslenme tedavisi, fiziksel aktivite dışında yeni tedavi yöntemleri için alternatif yollar aranmaktadır. Bitkisel destekler, çok az yan etkiye sahip oldukları ve popülasyonun çoğu tarafından kolayca ulaşılabilir olduğu için iyi bir alternatif olarak görülmekte ve bu konuda araştırmalar yapılmaktadır. Yüzyıllardır geleneksel bir ilaç olarak kullanılan tarçın da diyabet semptomlarına karşı en fazla kullanılan bitkisel desteklerden biridir. Cinnamomum cassia (Cinnamomum aromaticum veya Çin tarçını), Cinnamomum zeylanicum (Cinnamomum verum veya Seylan tarçını), Cinnamomum burmannii (Endonezya/Java tarçını) ve Cinnamomum loureiroi (Saygon/Vietnam tarçını) en yaygın tarçın türleri olarak kullanılmaktadır. Çeşitli çalışmalarda tarçının diyabetik olmayan, prediyabetli ve Tip 2 diyabetli bireylerde kan şekeri, tokluk kan şekeri, insülin, HbA1c gibi kan parametreleri üzerindeki etkisi araştırılmıştır.
Çalışmalar incelendiğinde sonuçlar arasında heterojenlik olduğu görülmekte ve tarçının kan şekerini düşürmede yararlı etkilerinin olduğuna dair kesin sonuçlara ulaşılamamaktadır. Bu nedenle diyabeti
olan bireylerde mevcut literatür bilgileri göz önünde bulundurularak beslenme tedavisi ve yaşam tarzı değişikliklerinin önerilmesi tavsiye edilmektedir.

References

  • Alphan ME. Diabetes Mellitus ve Beslenme Tedavisi. Hastalıklarda Tıbbi Beslenme Tedavisi. Editör: Emel Alphan, Hatiboğlu Yayınları, 6. Baskı, 2022, Ankara, 427-533 ISBN:978-605-9541-25-1.
  • Ota, A., & Ulrih, N. P. (2017). An overview of herbal products and secondary metabolites used for management of type two diabetes. Frontiers in pharmacology, 8, 436.
  • International Diabetes Federation IDF Diabetes Atlas-8 th edition, 2017
  • Deyno, S., Eneyew, K., Seyfe, S., Tuyiringire, N., Peter, E. L., Muluye, R. A., ... & Ogwang, P. E. (2019). Efficacy and safety of cinnamon in type 2 diabetes mellitus and pre-diabetes patients: a meta-analysis and meta-regression. diabetes research and clinical practice, 156, 107815.
  • Shang, C., Lin, H., Fang, X., Wang, Y., Jiang, Z., Qu, Y., ... & Cui, X. (2021). Beneficial effects of cinnamon and its extracts in the management of cardiovascular diseases and diabetes. Food & Function.
  • Ranasinghe, P., Galappaththy, P., Constantine, G. R., Jayawardena, R., Weeratunga, H. D., Premakumara, S., & Katulanda, P. (2017). Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized
  • Ríos, J. L., Francini, F., & Schinella, G. R. (2015). Natural products for the treatment of type 2 diabetes mellitus. Planta medica, 81(12/13), 975-994.
  • Vanschoonbeek K, Thomassen BJ, Senden JM, Wodzig WK, van Loon LJ. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. J Nutr 2006; 136: 977–980
  • Medagama, A. B. (2015). The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials. Nutrition journal, 14(1), 1-12.
  • Zare, R., Nadjarzadeh, A., Zarshenas, M. M., Shams, M., & Heydari, M. (2019). Efficacy of cinnamon in patients with type II diabetes mellitus: A randomized controlled clinical trial. Clinical nutrition, 38(2), 549-556.).
  • Careyva, B., Greenberg, G., Jabbour, K., Defenbaugh, N., & Nashelsky, J. (2020). Do cinnamon supplements improve glycemic control in adults with T2DM?.
  • Mirfeizi, M., Mehdizadeh Tourzani, Z., Mirfeizi, S. Z., Asghari Jafarabadi, M., Rezvani, H. R., & Afzali, M. (2016). Controlling type 2 diabetes mellitus with herbal medicines: A triple‐blind randomized clinical trial of efficacy and safety: Journal of diabetes, 8(5), 647-656.
  • Talaei, B., Amouzegar, A., Sahranavard, S., Hedayati, M., Mirmiran, P., & Azizi, F. (2017). Effects of cinnamon consumption on glycemic indicators, advanced glycation end products, and antioxidant status in type 2 diabetic patients. Nutrients, 9(9), 991.
  • Namazi, N., Khodamoradi, K., Khamechi, S. P., Heshmati, J., Ayati, M. H., & Larijani, B. (2019). The impact of cinnamon on anthropometric indices and glycemic status in patients with type 2 diabetes: A systematic review and meta-analysis of clinical trials. Complementary therapies in medicine, 43, 92-101.
  • Zahmatkesh M, Fallah Huseini H, Hajiaghaee R, Heidari M, Mehrafarin A, Tavakolifar B. The effects of Cinnamomum zeylanicum J. Presl on blood glucose level in patients with type 2 diabetes, a double-blind clinical trial. J Med Plants. 2012;1(41): 258–63.
  • Magistrelli A, Chezem J. Effect of ground cinnamon on postprandial blood glucose concentrations in normal-weight and obese adults. J Acad Nutr Diet. 2012;112:1806Y1809.
  • Bernardo M, Silva M, Santos E, et al. Effect of cinnamon tea on postprandial glucose concentration. J Diab Res. 2015;2015:913651.
  • Markey O, McClean C, Medlow P, et al. Effect of cinnamon on gastric emptying, arterial stiffness, postprandial lipemia, glycemia, and appetite responses to high-fat breakfast. Cardiovasc Diabetol. 2011;10:78Y86.
  • Ranasinghe P, Jayawardena R, Pigera S, et al. Evaluation of pharmacodynamic properties and safety of Cinnamomum zeylanicum (Ceylon cinnamon) in healthy adults: a phase I clinical trial. BMS Complement Altern Med. 2017;17:550Y558.
  • Kizilaslan, N., & Erdem, N. Z. (2019). The effect of different amounts of cinnamon consumption on blood glucose in healthy adult individuals. International journal of food science, 2019.
  • Wang, J., Wang, S., Yang, J., Henning, S. M., Ezzat-Zadeh, Z., Woo, S. L., ... & Li, Z. (2021). Acute effects of cinnamon spice on postprandial glucose and insulin in normal weight and overweight/obese subjects: A pilot study. Frontiers in nutrition, 7, 619782.
  • Bernardo, M. A., Silva, M. L., Santos, E., Moncada, M. M., Brito, J., Proença, L., ... & de Mesquita, M. F. (2015). Effect of cinnamon tea on postprandial glucose concentration. Journal of diabetes research, 2015.
  • Rachid, A. P., Moncada, M., Mesquita, M. F. D., Brito, J., Bernardo, M. A., & Silva, M. L. (2022). Effect of Aqueous Cinnamon Extract on the Postprandial Glycemia Levels in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial. Nutrients, 14(8), 1576.
  • Hajimonfarednejad, M., Ostovar, M., Raee, M. J., Hashempur, M. H., Mayer, J. G., & Heydari, M. (2019). Cinnamon: A systematic review of adverse events. Clinical Nutrition, 38(2), 594-602.
  • Vázquez-Fresno, R., Rosana, A. R. R., Sajed, T., Onookome-Okome, T., Wishart, N. A., & Wishart, D. S. (2019). Herbs and spices-biomarkers of intake based on human intervention studies–a systematic review. Genes & nutrition, 14(1), 1-27.
  • Costello, R. B., Dwyer, J. T., Saldanha, L., Bailey, R. L., Merkel, J., & Wambogo, E. (2016). Do cinnamon supplements have a role in glycemic control in type 2 diabetes? A narrative review. Journal of the Academy of Nutrition and Dietetics, 116(11), 1794-1802.
Year 2023, , 42 - 49, 09.03.2023
https://doi.org/10.54270/atljm.2023.30

Abstract

References

  • Alphan ME. Diabetes Mellitus ve Beslenme Tedavisi. Hastalıklarda Tıbbi Beslenme Tedavisi. Editör: Emel Alphan, Hatiboğlu Yayınları, 6. Baskı, 2022, Ankara, 427-533 ISBN:978-605-9541-25-1.
  • Ota, A., & Ulrih, N. P. (2017). An overview of herbal products and secondary metabolites used for management of type two diabetes. Frontiers in pharmacology, 8, 436.
  • International Diabetes Federation IDF Diabetes Atlas-8 th edition, 2017
  • Deyno, S., Eneyew, K., Seyfe, S., Tuyiringire, N., Peter, E. L., Muluye, R. A., ... & Ogwang, P. E. (2019). Efficacy and safety of cinnamon in type 2 diabetes mellitus and pre-diabetes patients: a meta-analysis and meta-regression. diabetes research and clinical practice, 156, 107815.
  • Shang, C., Lin, H., Fang, X., Wang, Y., Jiang, Z., Qu, Y., ... & Cui, X. (2021). Beneficial effects of cinnamon and its extracts in the management of cardiovascular diseases and diabetes. Food & Function.
  • Ranasinghe, P., Galappaththy, P., Constantine, G. R., Jayawardena, R., Weeratunga, H. D., Premakumara, S., & Katulanda, P. (2017). Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized
  • Ríos, J. L., Francini, F., & Schinella, G. R. (2015). Natural products for the treatment of type 2 diabetes mellitus. Planta medica, 81(12/13), 975-994.
  • Vanschoonbeek K, Thomassen BJ, Senden JM, Wodzig WK, van Loon LJ. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. J Nutr 2006; 136: 977–980
  • Medagama, A. B. (2015). The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials. Nutrition journal, 14(1), 1-12.
  • Zare, R., Nadjarzadeh, A., Zarshenas, M. M., Shams, M., & Heydari, M. (2019). Efficacy of cinnamon in patients with type II diabetes mellitus: A randomized controlled clinical trial. Clinical nutrition, 38(2), 549-556.).
  • Careyva, B., Greenberg, G., Jabbour, K., Defenbaugh, N., & Nashelsky, J. (2020). Do cinnamon supplements improve glycemic control in adults with T2DM?.
  • Mirfeizi, M., Mehdizadeh Tourzani, Z., Mirfeizi, S. Z., Asghari Jafarabadi, M., Rezvani, H. R., & Afzali, M. (2016). Controlling type 2 diabetes mellitus with herbal medicines: A triple‐blind randomized clinical trial of efficacy and safety: Journal of diabetes, 8(5), 647-656.
  • Talaei, B., Amouzegar, A., Sahranavard, S., Hedayati, M., Mirmiran, P., & Azizi, F. (2017). Effects of cinnamon consumption on glycemic indicators, advanced glycation end products, and antioxidant status in type 2 diabetic patients. Nutrients, 9(9), 991.
  • Namazi, N., Khodamoradi, K., Khamechi, S. P., Heshmati, J., Ayati, M. H., & Larijani, B. (2019). The impact of cinnamon on anthropometric indices and glycemic status in patients with type 2 diabetes: A systematic review and meta-analysis of clinical trials. Complementary therapies in medicine, 43, 92-101.
  • Zahmatkesh M, Fallah Huseini H, Hajiaghaee R, Heidari M, Mehrafarin A, Tavakolifar B. The effects of Cinnamomum zeylanicum J. Presl on blood glucose level in patients with type 2 diabetes, a double-blind clinical trial. J Med Plants. 2012;1(41): 258–63.
  • Magistrelli A, Chezem J. Effect of ground cinnamon on postprandial blood glucose concentrations in normal-weight and obese adults. J Acad Nutr Diet. 2012;112:1806Y1809.
  • Bernardo M, Silva M, Santos E, et al. Effect of cinnamon tea on postprandial glucose concentration. J Diab Res. 2015;2015:913651.
  • Markey O, McClean C, Medlow P, et al. Effect of cinnamon on gastric emptying, arterial stiffness, postprandial lipemia, glycemia, and appetite responses to high-fat breakfast. Cardiovasc Diabetol. 2011;10:78Y86.
  • Ranasinghe P, Jayawardena R, Pigera S, et al. Evaluation of pharmacodynamic properties and safety of Cinnamomum zeylanicum (Ceylon cinnamon) in healthy adults: a phase I clinical trial. BMS Complement Altern Med. 2017;17:550Y558.
  • Kizilaslan, N., & Erdem, N. Z. (2019). The effect of different amounts of cinnamon consumption on blood glucose in healthy adult individuals. International journal of food science, 2019.
  • Wang, J., Wang, S., Yang, J., Henning, S. M., Ezzat-Zadeh, Z., Woo, S. L., ... & Li, Z. (2021). Acute effects of cinnamon spice on postprandial glucose and insulin in normal weight and overweight/obese subjects: A pilot study. Frontiers in nutrition, 7, 619782.
  • Bernardo, M. A., Silva, M. L., Santos, E., Moncada, M. M., Brito, J., Proença, L., ... & de Mesquita, M. F. (2015). Effect of cinnamon tea on postprandial glucose concentration. Journal of diabetes research, 2015.
  • Rachid, A. P., Moncada, M., Mesquita, M. F. D., Brito, J., Bernardo, M. A., & Silva, M. L. (2022). Effect of Aqueous Cinnamon Extract on the Postprandial Glycemia Levels in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial. Nutrients, 14(8), 1576.
  • Hajimonfarednejad, M., Ostovar, M., Raee, M. J., Hashempur, M. H., Mayer, J. G., & Heydari, M. (2019). Cinnamon: A systematic review of adverse events. Clinical Nutrition, 38(2), 594-602.
  • Vázquez-Fresno, R., Rosana, A. R. R., Sajed, T., Onookome-Okome, T., Wishart, N. A., & Wishart, D. S. (2019). Herbs and spices-biomarkers of intake based on human intervention studies–a systematic review. Genes & nutrition, 14(1), 1-27.
  • Costello, R. B., Dwyer, J. T., Saldanha, L., Bailey, R. L., Merkel, J., & Wambogo, E. (2016). Do cinnamon supplements have a role in glycemic control in type 2 diabetes? A narrative review. Journal of the Academy of Nutrition and Dietetics, 116(11), 1794-1802.
There are 26 citations in total.

Details

Primary Language Turkish
Subjects Nutrition and Dietetics (Other)
Journal Section Reviews
Authors

Ayşe Betül Demirbaş This is me 0000-0003-2765-2677

Müveddet Emel Alphan This is me

Publication Date March 9, 2023
Published in Issue Year 2023

Cite

Vancouver Demirbaş AB, Alphan ME. TARÇIN GERÇEKTEN KAN ŞEKERİNİ DÜŞÜRÜYOR MU?. ATLJM. 2023;2(6):42-9.