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YAŞ GRUPLARI VE ŞIKAYET SÜRELERINE GÖRE FONKSIYONEL KABIZLIĞI OLAN ÇOCUKLARIN KLINIK BULGULARI: BIR MERKEZ DENEYIMI

Year 2023, Volume: 2 Issue: 6 - February 2023, 2 - 12, 09.03.2023
https://doi.org/10.54270/atljm.2023.26

Abstract

Amaç: Kabızlık dünya çapında en yaygın pediatrik sorunlardan biridir. Bu çalışmanın amacı, fonksiyonel kabızlığı olan çocukların klinik özelliklerini belirlemek, yaş gruplarına ve kabızlık sürelerine göre farklılıkları tartışmaktır.
Yöntemler: Retrospektif olarak, pediatrik gastroenteroloji polikliniğimizde tedavi edilen fonksiyonel kabızlığı olan tüm hastalar dahil edildi.
Bulgular: Bu çalışmaya ortalama ± SEM yaşı 61,2 ± 2,3 ay olan 251 (%57,4) kadın ve 186 (%42,6) erkek dahil edildi. Ortalama ± SD konstipasyon süresi 18.5 ± 1.1 aydı. Kabızlık süresinin artan yaşla birlikte arttığı bulundu (p <0.0001 eğilimi için). Sert ve iri dışkı insidansı yaşla birlikte anlamlı artış gösterirken (p<0.0001), pelet benzeri dışkı insidansı yaşla birlikte giderek azaldı (p<0.0001). Defekasyon sıklığı artan yaşla birlikte anlamlı olarak daha az yaygındı (p<0.0001). Anal fissür en sık 1-24 ay arasında %50 ile görüldü (p<0,0001).
Sonuç: Yaş grubu ve konstipasyon süresine göre bazı klinik özelliklerin ön plana çıktığı görüldü. Tedavinin farklı klinik özelliklere ve bu tedaviye verilen cevaba göre seçilmesinin gerekip gerekmediğini belirlemek için daha ileri çalışmalara ihtiyaç vardır.

References

  • Benninga MA, Voskuijl WP, Taminiau JA. Childhood constipation: Is there new light in the tunnel? J Pediatr Gastroenterol Nutr 2004; 39: 448-464
  • Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: A systematic review. Best Pract Res Clin Gastroenterol 2011; 25: 3-18
  • Loening-Baucke V. Chronic constipation in children. Gastroenterology 1993; 105: 1557-1564
  • Molnar D, Taitz LS, Urwin OM, Wales JK. Anorectal manometry results in defecation disorders. Arch Dis Child 1983; 58: 257-261
  • Taitz LS, Wales JK, Urwin OM, Molnar D. Factors associated with outcome in management of defecation disorders. Arch Dis Child 1986; 61: 472-477
  • Kuloğlu Z, Girgin N. Çocukluk çağında kabızlık. Türkiye Klinikleri J Pediatr Sci 2005; 1(8): 6-14
  • Dehghani SM, Kulouee N, Honar N, Imanieh MH, Haghighat M, Javaherizadeh H. Clinical manifestations among children with chronic functional constipation. Middle East J Dig Dis 2015; 7(1): 31-35
  • Mederios LC, Morais MB, Tahan S, Fukushima E, Motta ME, Fagundes-Neto U. Clinical characteristics of pediatric patients with chronic constipation according to age group. Arq Gastroenterol 2007; 44: 340 344
  • Zeevenhooven J, Koppen IJN, Benninga MA, The new Rome IV criteria for functional gastrointestinal disorders in infants and toddlers. Ped Gastroenterol Hepatol Nutr 2017; 20: 1-13
  • Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology 2016; 150: 1456-1468
  • Ip KS, Lee WT, Chan JS, Young BW. A community-based study of the prevalence of constipation in young children and role of dietary fibre. Hong Kong Med J 2005; 11: 431-436
  • Kajiwara M, Inoie K, Usui A, Kurihara M, Usui T. The mictirition habits and prevalance of day time urinary incontinance in Japanase Primary school children. J Urol 2004; 171: 403-407
  • Van Ginkel R, Reitsma JB, Buller HA, et al. Childhood constipation: longitudinal follow up beyond puberty. Gastroenterology 2003; 125: 357- 363
  • de Lorjin F, van Wijk MP, Reitsma JB, Taminiau JAJM, Benninga MA. Prognosis of constipation: clinical factors and colonic transit time. Arch Dis Child 2004; 89: 723-727
  • van den Berg MM, van Rossum CH, de Lorjin F, et al. Functional constipation in infants: a follow up study. J Pediatr 2005; 147: 700-704
  • Aydoğdu S, Çakır M, Yüksekkaya HA, Arıkan Ç, Tümör G, Baran M, Yağcı RV. Chronic constipation in Turkish children: clinical findings and applicability of classification criteria. Turk J Pediatr 2009; 51: 146-153
  • Kocabay P, Eğritaş Ö, Dalgıç B. Normal defecation pattern, frequency of constipation and factors related to constipation in Turkish children 0-6 years old. Turk J Gastroenterol 2011, 22(4): 369-375
  • Baucke LV. Constipation in early childhood: patient characteristics, treatment and long term follow-up. Gut 1993; 34: 1400-1404
  • Amendola S, DeAngelsis P, Dall’Oglio L, Di Abriola F, Di Lorenzo M. Combined approach to functional constipation in children. J Pediatr Surg 2003; 38: 819-823
  • Sarı Y, Doğan Y. Kabızlık yakınması olan olgularda klinik bulguların, etyolojik nedenlerin ve izlem sonuçlarının değerlendirilmesi. F.Ü. Sağ. Bil. Tıp Derg. 2012; 26(3): 121-125
  • Şahin S, Gülerman F, Köksal T, Köksal AO. Çocuklarda kronik kabızlık olgularının değerlendirilmesi. Turkish J Pediatr Dis 2014; 3: 117-123
  • van den Berg MM, Benninga MA, Di Lorenzo C. Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol 2006; 101: 2401-2409
  • Altamimi E. Clinical characteristics of pediatric constipation in South Jordan. Pediatr Gastroenterol Hepatol Nutr 2014; 17(3): 155-161
  • Chang SH, Park KY, Kang SK, Kang KS, Na SY, Yang HR, Uhm JH, Ryoo E. Prevalance, clinical characteristics, and management of functional constipation at pediatric gastroenterology clinics. J Korean Med Sci 2013; 28: 1356-1361
  • Doğan Y, Ergün Y, Çokuğraş FC, Kutlu T. Kabızlık yakınması olan olguların retrospektif dökümü. Türk Pediatri Arşivi 2005; 40: 23-27
  • Gijsbers CM, Kneepkens CMF, Vergouwe Y, Büller H. Occult constipation: faecal retention as a cause of recurrent abdominal pain in children. Eur J Pediatr 2014; 473: 784-785
  • Ali MW, Sabir OM, ElHassanGadour MO.Pattern and clinical presentation of constipation in children in Sudan. Sudan J Med Sci 2013; 7: 229-231
  • Loening-Baucke V, PashankarDS. A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence. Pediatrics 2006; 118: 528-535
  • Loening-Baucke V. Prevalence rates for constipation and faecal and urinary incontinance Arc Dis Child 2007; 92: 486-489
  • van Ginkel R, Reitsma JB, Buller HA, van Wijk MP, Taminiau JA, Benninga MA. Childhood constipation: longitudinal follow up beyond puberty. Gastroenterology 2003; 125: 357-363
  • Bacer SS, Liptak GS, Coletti RB, et al. Constipation in infants and children: evaluation and treatment. A medical statement of the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr 1999; 29: 612-626.
  • Abrahamian FP, Lloyd-Still JD. Chronic constipation in childhood: A longitudinal study of 186 patients. J Pediatr Gastroenterol Nutr 1984; 3: 460-467
  • Guerrero RA, Cavender CP. Constipation: Physical and psychological sequelae. Pediatr Ann 1999; 28: 312-316.

CLINICAL FINDINGS OF FUNCTIONAL CONSTIPATION IN CHILDHOOD ACCORDING TO THE DIFFERENT AGE GROUPS AND DURATION OF SYMPTOMS: ONE CENTER EXPERIENCE

Year 2023, Volume: 2 Issue: 6 - February 2023, 2 - 12, 09.03.2023
https://doi.org/10.54270/atljm.2023.26

Abstract

Objective: Constipation is one of the most prevalent global pediatric problem. The aim of our study was to identify the clinical distinctive of children with functional constipation and to discuss the differences according to age groups and durations of constipation.
Methods: Retrospectively, all children with functional constipation cured at our pediatric gastroenterology outpatients department were included.
Results: This study included 251 (57.4%) females and 186 (42.6%) males with a mean ± SEM age of 61.2 ± 2.3 months. The mean ± SD constipation duration was 18.5 ± 1.1 months. The constipation duration was
found to increase with increasing age (p for trend <0.0001). While the incidence of hard and large stools showed a significant rise with increasing age (p<0.0001), pellet-like stool incidence gradually diminished with increasing age (p<0.0001). Defecation frequency was significantly less common with increasing age (p<0.0001). Anal fissure was the most common in the 1-24 months age group at a rate of 50% (p<0.0001).
Conclusion: Certain clinical characteristics were seen to become emphasized according to the age group and constipation duration. Further studies are needed to determine whether treatment should be chosen according to the different clinical characteristics and the response to such treatment.

References

  • Benninga MA, Voskuijl WP, Taminiau JA. Childhood constipation: Is there new light in the tunnel? J Pediatr Gastroenterol Nutr 2004; 39: 448-464
  • Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: A systematic review. Best Pract Res Clin Gastroenterol 2011; 25: 3-18
  • Loening-Baucke V. Chronic constipation in children. Gastroenterology 1993; 105: 1557-1564
  • Molnar D, Taitz LS, Urwin OM, Wales JK. Anorectal manometry results in defecation disorders. Arch Dis Child 1983; 58: 257-261
  • Taitz LS, Wales JK, Urwin OM, Molnar D. Factors associated with outcome in management of defecation disorders. Arch Dis Child 1986; 61: 472-477
  • Kuloğlu Z, Girgin N. Çocukluk çağında kabızlık. Türkiye Klinikleri J Pediatr Sci 2005; 1(8): 6-14
  • Dehghani SM, Kulouee N, Honar N, Imanieh MH, Haghighat M, Javaherizadeh H. Clinical manifestations among children with chronic functional constipation. Middle East J Dig Dis 2015; 7(1): 31-35
  • Mederios LC, Morais MB, Tahan S, Fukushima E, Motta ME, Fagundes-Neto U. Clinical characteristics of pediatric patients with chronic constipation according to age group. Arq Gastroenterol 2007; 44: 340 344
  • Zeevenhooven J, Koppen IJN, Benninga MA, The new Rome IV criteria for functional gastrointestinal disorders in infants and toddlers. Ped Gastroenterol Hepatol Nutr 2017; 20: 1-13
  • Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology 2016; 150: 1456-1468
  • Ip KS, Lee WT, Chan JS, Young BW. A community-based study of the prevalence of constipation in young children and role of dietary fibre. Hong Kong Med J 2005; 11: 431-436
  • Kajiwara M, Inoie K, Usui A, Kurihara M, Usui T. The mictirition habits and prevalance of day time urinary incontinance in Japanase Primary school children. J Urol 2004; 171: 403-407
  • Van Ginkel R, Reitsma JB, Buller HA, et al. Childhood constipation: longitudinal follow up beyond puberty. Gastroenterology 2003; 125: 357- 363
  • de Lorjin F, van Wijk MP, Reitsma JB, Taminiau JAJM, Benninga MA. Prognosis of constipation: clinical factors and colonic transit time. Arch Dis Child 2004; 89: 723-727
  • van den Berg MM, van Rossum CH, de Lorjin F, et al. Functional constipation in infants: a follow up study. J Pediatr 2005; 147: 700-704
  • Aydoğdu S, Çakır M, Yüksekkaya HA, Arıkan Ç, Tümör G, Baran M, Yağcı RV. Chronic constipation in Turkish children: clinical findings and applicability of classification criteria. Turk J Pediatr 2009; 51: 146-153
  • Kocabay P, Eğritaş Ö, Dalgıç B. Normal defecation pattern, frequency of constipation and factors related to constipation in Turkish children 0-6 years old. Turk J Gastroenterol 2011, 22(4): 369-375
  • Baucke LV. Constipation in early childhood: patient characteristics, treatment and long term follow-up. Gut 1993; 34: 1400-1404
  • Amendola S, DeAngelsis P, Dall’Oglio L, Di Abriola F, Di Lorenzo M. Combined approach to functional constipation in children. J Pediatr Surg 2003; 38: 819-823
  • Sarı Y, Doğan Y. Kabızlık yakınması olan olgularda klinik bulguların, etyolojik nedenlerin ve izlem sonuçlarının değerlendirilmesi. F.Ü. Sağ. Bil. Tıp Derg. 2012; 26(3): 121-125
  • Şahin S, Gülerman F, Köksal T, Köksal AO. Çocuklarda kronik kabızlık olgularının değerlendirilmesi. Turkish J Pediatr Dis 2014; 3: 117-123
  • van den Berg MM, Benninga MA, Di Lorenzo C. Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol 2006; 101: 2401-2409
  • Altamimi E. Clinical characteristics of pediatric constipation in South Jordan. Pediatr Gastroenterol Hepatol Nutr 2014; 17(3): 155-161
  • Chang SH, Park KY, Kang SK, Kang KS, Na SY, Yang HR, Uhm JH, Ryoo E. Prevalance, clinical characteristics, and management of functional constipation at pediatric gastroenterology clinics. J Korean Med Sci 2013; 28: 1356-1361
  • Doğan Y, Ergün Y, Çokuğraş FC, Kutlu T. Kabızlık yakınması olan olguların retrospektif dökümü. Türk Pediatri Arşivi 2005; 40: 23-27
  • Gijsbers CM, Kneepkens CMF, Vergouwe Y, Büller H. Occult constipation: faecal retention as a cause of recurrent abdominal pain in children. Eur J Pediatr 2014; 473: 784-785
  • Ali MW, Sabir OM, ElHassanGadour MO.Pattern and clinical presentation of constipation in children in Sudan. Sudan J Med Sci 2013; 7: 229-231
  • Loening-Baucke V, PashankarDS. A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence. Pediatrics 2006; 118: 528-535
  • Loening-Baucke V. Prevalence rates for constipation and faecal and urinary incontinance Arc Dis Child 2007; 92: 486-489
  • van Ginkel R, Reitsma JB, Buller HA, van Wijk MP, Taminiau JA, Benninga MA. Childhood constipation: longitudinal follow up beyond puberty. Gastroenterology 2003; 125: 357-363
  • Bacer SS, Liptak GS, Coletti RB, et al. Constipation in infants and children: evaluation and treatment. A medical statement of the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr 1999; 29: 612-626.
  • Abrahamian FP, Lloyd-Still JD. Chronic constipation in childhood: A longitudinal study of 186 patients. J Pediatr Gastroenterol Nutr 1984; 3: 460-467
  • Guerrero RA, Cavender CP. Constipation: Physical and psychological sequelae. Pediatr Ann 1999; 28: 312-316.
There are 33 citations in total.

Details

Primary Language English
Subjects Gastroenterology and Hepatology
Journal Section Research Articles
Authors

Mahya Sultan Tosun This is me 0000-0001-7582-0255

Publication Date March 9, 2023
Published in Issue Year 2023 Volume: 2 Issue: 6 - February 2023

Cite

Vancouver Tosun MS. CLINICAL FINDINGS OF FUNCTIONAL CONSTIPATION IN CHILDHOOD ACCORDING TO THE DIFFERENT AGE GROUPS AND DURATION OF SYMPTOMS: ONE CENTER EXPERIENCE. ATLJM. 2023;2(6):2-12.