Deksametazonun Sıçan Karaciğer Hücrelerine Etkisinin İnce Yapı Düzeyinde İncelenmesi

Year 1990, Volume: 43 Issue: 3 , 795 - 802 , 30.09.1990

Yüksel Saran

https://izlik.org/JA32NB35TS

Abstract

Sıçan karaciğer hücreleri 24 saatlik bir açlık periyodundan ve bunun sonunda dekzametazon verilmesinden sonra ince yapı düzeyinde incelendi ve kontrol gurupları ile kararlaştırıldı. Aç bırakılan hayvanların karaciğer hücrelerinde agranüler retikulum keseeleri az sayıda ve glikojen tanecikleri çok seyrek görülürken, dekzametazon verilmesinden sonra agranüler retikulum keseleri ve glikojen granil-.lerinde belirgin artış gözlendi.

Keywords

karaciger hticreleri , agrantiler retikulum , aghk periyodu

Project Number

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Fine Structural Observations of Rat Liver Cells Treated With Dexamethasone

https://izlik.org/JA32NB35TS

Abstract

After 24 hour unfeded period, rat liver cells treated with dexamethasone and cells then observed for fine stuctural level and compared
with control groups. In liver cells of the unfeded animals, agranuler endoplasmic reticulums were afew and glycogen particules werescarce. After the dexametasome treatment, -cconsidérable increase. in agranuler reticulums and abundant glycogen particules- were observed.

Keywords

glycogen particules , animals , control groups.

Supporting Institution

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Project Number

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Thanks

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References

• Carolyn D : Role of ghacecorticeids in: the. regulation of lipogenssis: Fasep J-3:2179-2183, 1989.
• Carlo MD Keit B Porter PD : The fine structune of the parenchymal cell of the normal rat liver Am J pato 46 : 681, 755, 1955.
• Deman JCD Blocak APR : Relationship between glycogen and agranuler encoplasmic reticulum in rat hepatit cel’s. ilisto and cyto. 14: 185-144, 1966.Grill V Runfeldt M ; Abnormalities of inculin responses after ambient and previous exposure to glikose in streptozocin - diabetic and cexametazone treated rats. Diabetes. 35 : 44-51, 1986.
• James AG Theresa AR : Desensitization of primary cultures of adult rat liver paranchymal cells to stimulation of adenosine 3’.5° - monophosphate production by glucagon and epinephine Endoc. 107: 1309-1319, 1930.
• Odette M Claire N : Long-term maintenance of hepatocyte functional activityin co-culture : Requirements for sinusaidal endothelial cells and dexametasone. J cell physiol. 129 : 103-110, 1886.
• Margolis RN Cardelli RR Cumow RT: Association of glycogen synthase phosphatase and phosphorylase smnooth endosplasmic reticulum. J cell biology, 83 :. 348-356, 1979. Muriel B Robert R Cardell JR: Fine structure of hepatocytes from fasted and fod rats Am J. Anat. 143 : 399-438, 1974. Robert R Cardell JR : Action of metabolic hormones on the fine structure of ratliver cells Am J Anat. 139 : 49-80, 1947.
• Robert R Cardell JB : Action of metabolic hormones on the fine structure of: ratliver cells Am J Anat, 131: 21-54, 1971. Robert R Cardell JR ve ark : Correlation between structure and glycogen contend of livers from rats on a controlled feeding schdule. Anat. Rec. 177 : 23-38, 1879802
• 14.Robert R Cardell JR : Action of metabolic hormones on the fine structure of rat liver cells Anat. Rec. 180 : 309-330, 1974.
• Ronald NM Robert R Cardell JR : Effects of actinomycin D on dexamethasone induced hepatic glycogen accumulation. Morphological and biochemical observations. Am J Anat. 158 : 365-386, 1980. Takash S Hiroshi T : Specific binding sites for natural glucocorticoids in plas- - ma membranes of rat liver. Endoc. 96 : 1499-1508, 1975.