Uterus Myomlarının Etyolojisinde Hormonal Teori Üzerine
Abstract
This study retrospectively analyzes 148 cases of uterine myoma diagnosed and treated with total hysterectomy and salpingo-oophorectomy at Ankara University Faculty of Medicine, Department of Obstetrics and Gynecology between 1960 and 1972. Histopathological evaluations of endometrial and ovarian tissues were performed to assess the role of estrogen in the etiology of uterine myomas. The majority of cases demonstrated endometrial hyperplasia and follicular cysts or degenerative changes in the ovaries. These findings support the theory that hormonal imbalance, particularly hyperestrogenism, plays a significant role in the development of myomas. However, the presence of myomas in some hormonally normal cases suggests that multiple etiological factors may be involved.
Keywords
Uterine myoma, hormonal theory, estrogen, endometrial hyperplasia, follicular cyst, histopathology, hysterectomy
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