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Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi

Year 1971, Volume: 24 Issue: 1, 34 - 61, 28.02.1971
https://izlik.org/JA92EZ27SX

Abstract

The Effects of the High Pressure on the Body Temperature and the Oxidation • Reduction potential of Blood.
The effects of the high pressure air atmosphere on the body temperature (blood, liver and muscle) as well as the oxidation-reduction potential of blood have been investigated. The findings are summerized as follow :
1 — The body temperature recorded from blood, liver and skeletal muscle diminishes under hyperbaric conditions.
2 — Temperature diminition becomes more prominent as much as the surrounding atmospherial pressure is increosed as well as the duration of the experiment is prolonged.
3 — The most prominent fall in temperature is observed on the skeletal muscle, and a modarate diminition is seen on the blood and liver respectively.
4 — The oxidation-reduction potential of blood decreased in relation with the icrease in ambien pressure.
The above mentioned findings and especially the decrease in the oxidation-reduction potential of blood parallel to the decrease in the body temperature suggests that the lovering of the body temperature under the hyperbaric conditions may be related to the fermentatif blokage in the cells responsible from the heat formation.
The effects of CO. and Hydrogen ion concentration affected by the hyperbaric 02 atmospher is also discussed.

References

  • 1 — AKÇAY, M. • Sinir sistemi Fizyolojisi. A.Ü. TIP Fak. yaylnl. 108-110, 195
  • 2 — ANDERSEN, T.H. : Physiological adaptation in diving vertebrates Physiol. Rev. 46: 212, 1966.
  • 3 — ANDERSEN, T. H., HUSTVEDT, B. E. : Acid-base change in diving ducts. Acta Physiol. Scand. 63: 128, 1965.
  • 4 — AQUADRO, C. F., CHOUTEAU, J. : Problems of ekstreme duration in open sea saturation exposure. Proccedings of the thirt symposium on underwater physiology. Will. Wilk. Co. Baltimore 98-108, 1967.
  • 5 — BARROWS, E. F., DODDS, H. : Body temperature of mice during anesthesia. Am. J. Physiol. 137 : 259, 1942.
  • 6 — BEHNKE, A. R. : High atmospheric pressures; physiological effects of incereased and decreased pressure, application of these findings to clinical medicine. Ann. Internal Med. 13 2217, 1940.
  • BERTHARION, G. : Toxicité de l'oxygéne hyperbare, effect aigu, étude neurophysiologique. Ann. Chir. Thor. Cardiovasc. 5 : 861, 1966.
  • 8 — BEST, H. C., TAYLOR, B. N. : The Physiological Basis of Medical Practice. Will. Wilk. co. 1966.
  • 9 — BOEREMA, I. : L'oxygénation hyperbarique. Ann. Chir. Thor. Cardiovasc. 5 : 836, 1966.
  • 10 — BRUMMELKAMP, W. H. : Traitement des infections a germes anaerobies par l'inhalation d'oxiygéne en hyperpression. Ann. Chir. Thor. Cardiavasc. 5 : 839, 1966.
  • 11 — DAViDSON, J. K. : Avascular necrosis of bone. Hyperbaric oxygenetion procceding of the second international congress. Livingstone, London, 11, 1965.
  • 12 — DONALD, C. J. : Metabolic depression and oxygen depletion in the diving turtle. J. Appl. Physiol. 24 : 503, 1968.
  • 13 — DONALD, W. K. : Oxygen poisoning. Hyperbaric oxygenation Procee dings of the second international congrees. Livingstone, London, 26 1965.
  • 14 — FOLKOW, B., NILSSON, N. J., YONCE, L. R. : Effects of diving on cardiac autput in ducks. 12. Scandinavian congreess of physiology, Turku, 1966. Acta Physiol. Scand. 68, suppleemntum 277: 51, 1966.
  • 15 — FOSTER, A. C., DAVtDSON, C. 1. : Response to high pressure oxygen of concious valunteers and patints. J. Appl. Physiol. 18 : 492, 1963.
  • 16 — PREJAVILLE, J. P. : Toxicité de l'oxygene - Aspect blochimique. Ann. Chir. Thor. Cardiovac. 5 : 872, 1966.
  • 17 — GELINEO, S. : Adaptation to environment. Hand Book of Physiology, section 4, Washington D. C. 276, 1964.
  • 18 — GILL, B. M., PUGH, G. E. : Basal metabolism and respiration in men living at 5.800 m. (19.000 ft) J. Appl. Phpsiol. 19 : 949, 1964.
  • 19 — GOLDBERGER, E. : A. Primer of Water and Acid-Base Syndromes. Lea and Febiger, Philadelphia, 1965.
  • 20 — GOSSET, C. : Sur la toxicite de l'oxygene. Ann. Chir. Thor. cardiovasc. 5 : 870, 1966.
  • 21 — GAULLON, M., BARDIS, A., NOUAILHAT, F. : L'oxiygénothérapie hyper, bare. La Revue du Prat. 15 : 4397, 1965.
  • 22 — GUYTON, A. C. : Textbook of Medical Physiology. Third edition, W. B. Saunders Co. London, 637, 1966.
  • 23 — HARPER, A. H. : Review of Physiological Chemistry. 11 ed. lange Med. Publ. California. 159, 1967.
  • 24 — HAUGARD, N. : Cellular mechanism of oxygen toxicity. Physiol. Rev. 48 : 311, 1968.
  • 25 — HEMPLEMAN, H. V. : Decompression procedures for deep open sea operation. Proceedings of the Thirt Symposium on Underwater Physiology. Will. Wilk. co. Baltimore, 225, 1967.
  • 26 — HESSER, C. M. : Swedish naval interest in diving research. Proceedings of the Thirt Symposium on Underwater Physiology. Will. Wilk. Co. Baltimore, 16, 1967.
  • 27 — HOVEL, J. : Synthése et perpectives D'avenir (Journées Marseillaises d'Hyperbarie.) Ann. Chir. Thor. Cardiovasc. 5 : 874, 1966.
  • 28 — HUGUENARI), P. : Les Problémes physiques, techniques et biologiques Prosés par l'oxigénothérapie hypperbare. La Presse Med. 75 99, 1967.
  • 29 — HUYBRECHTS, M. : Le PH et sa Mesure. Masson Ed. 273, 1947.
  • 30 — ILLINGWORTH, F. W., LAWSON, 1., LEDINGHAM, 1., SHARP, G. R., GRIFFITHS, J. C. : Surgical and physiological observations in an experimental pressure chamber. Brit. J. Surg. 49 : 222, 1961.
  • 31 — JARRETT, A. S. : Alveolar carbon dioxide tension at increased ambient pressures. J. Appl. Physiol. 21 : 158, 1966.
  • 32 — JOZY, R. : Problémes soulevés dans le domaine de la recherce bilologique par l'utilization des atmosphéres hyperbares et hyperoxygénées. Ann. Chir. Thor. Cardiovac. 5 : 856, 1966.
  • 33 — LAMBERTSEN, C. J. : Proceedings of the Thirt Symposium on UnderWater Physiology. Will. Wilk. co. Baltimore, ix, 223-240, 480, 1967.
  • 34 — LANPHIER, E.H. : Influence of increased ambient pressure upon alveolar ventilation. Proceedings of The Second Symposium on Underwater Physiology. Natl. Acad. Sci., Natl.. Res. Council. Publ. 1181. Washington, 124, 1963.
  • 35 — LANPHIER, E. P., BUSBY, D. E. : Alveolar and PC02 in man under in creased ambient pressures. Proc. 22 intern. Congr. Physiol. Sci. 2: 1962.
  • 36 — LANPHIER, E. H., MORÌN, R.A. : Effects of gas density on carbondioxid elimination. Physiologist, 4: 63, 1961.
  • 37 — LANPHIER, E. H. : Handbook of Physiology. Adaptation to the environment. Section 4, Washington D. C. 893, 1964.
  • 38 — LEDINGHAM, I. M. : Hyperbaric Oxygenation. Livingston, London, 125, 1965.
  • 39 — MALMEJAC, J. : Bases physiologiques du l'utilisation de l'oxygene hyperbare. Ann. Chir. Thor. Cardiovasc, 5 : 827, 1966. 40 — NAIRN, J. R., POWER, G. G., HYDE, W. R., FORSTER, R. E., LAM. BERTSEN, C. J., DICKSON, J. : Diffusing capacity and pulmonary capillary blood flow at hyperbaric pressure. Clin. Invest. 44 : 1591, 1965.
  • 41 — RAYMOND, W. L. : Temperature problemes in multiday exposures to high pressures in the sea. Thermal balance in hyperbaric atmospheres. Proceeding of the Thirt Symposium on Underwater Physiology. Will. Wilk. co. Baltimore. 138, 1967.
  • 42 — SALZANO, J. V., BELL, H. W., WEGLICKI, W. B., SALTZMAN, H. A. : Metabolic, respiratory and hemodynamic responses to exedcise at increased oxygen pressure Procoedings of the Third Symposium on Underwater Physiology. Will. Wilk. Co. Baltimore. 351, 1967.
  • 43 — SCHOLANDER, P. F., HAMMEL, T. T., MESSURIER, H., HEMINGSON, E., GAREY, W. : Circulatory adustment in pearl divers. J. Appl. Physi01. 11: 184, 1962.
  • 44 — SHILLING, C., BENNETT, J. A., HEIM, J. W., THOMSON, R. M., DRINKER, C. H. : Bodily changes and devalopment of pulmonary resistance in rats living under compressed air conditions. J. Exptl. Med. 56: 63, 1932.
  • 45 — SODEMAN, A. W. : Pathologic Physiology. Second Ed. W. B. Saunders co. 289, 1961.
  • 46 — TERZiOÖLU M. : Fizyoloji Ders Kitabl. ismail Akgün Mat. istanbul, 376, 1962.
  • 47 — WHITE, N. F., ROSS, G. : Circulatory changes during experimental di• ving in the turtle. Am. J. Physiol. 211 : 15, 1966.

The Effect of High Pressure on Body Temperature and the Oxidation-Reduction Potential of Blood

Year 1971, Volume: 24 Issue: 1, 34 - 61, 28.02.1971
https://izlik.org/JA92EZ27SX

Abstract

Kedilerde, yüksek basıncın vücut ısısı ( kan, karaciğer, kas) ve kanın oksido-redüksiyon potansiyeli üzerine tesiri araştırılmıştır. 2—7 atmosfer hava basıncı altında yapılan deneylerde ısı, kan (vena cava inferior), karaciğer ve kastan yazdırılmış, kanın oksido—redüksiyon potansiyeli yine vena cava inferiordan ölçülmüştür.
2—7 atmosfer basınç altında yapılan deneylerden elde edilen bulgular kontrol deneyleri ile mukayese edilerek aşağıdaki sonuçlara varılmıştır.
1 Yüksek hava basıncına maruz bırakılan tecrübe hayvanlarında vücut ısısı düşmektedir.
2 — Ortam basıncı yükseldikçe ve basınca maruz kalma süresi uzadıkça ısı düşmesi artmaktadır.
3 — Yüksek basınç altında en fazla ısı düşmesi kasta, ikinci derecede karaciğerde, en az ısı düşmesi kanda olmaktadır.
4 — Ortam basıncının artması ile kan redoks—potansiyelinde bir azalma meydana gelmektedir.
Yüksek atmosfer basıncı altında husule gelen ısı düşmesine redoks—potansiyel azalmasının da refakat etmesi, ısı teşekkül mekanizmasındaki fermentatif oksidasyon olaylarında bir inhibisyo.n meydana gelmiş olduğunu telkin etmektedir. Bunun da, ortam basıncının yükselmesi ile organizmada artan oksijenin C02 transpor-
tunu bozup, pH düsmesine sebeb olmak ve enzimler üzerine tesir ederek aktivitelerini azaltmak sureti ile hiyolojik oksidasyonu bosmasmdan ileri gelebileceži münakasa edilmiştir.

References

  • 1 — AKÇAY, M. • Sinir sistemi Fizyolojisi. A.Ü. TIP Fak. yaylnl. 108-110, 195
  • 2 — ANDERSEN, T.H. : Physiological adaptation in diving vertebrates Physiol. Rev. 46: 212, 1966.
  • 3 — ANDERSEN, T. H., HUSTVEDT, B. E. : Acid-base change in diving ducts. Acta Physiol. Scand. 63: 128, 1965.
  • 4 — AQUADRO, C. F., CHOUTEAU, J. : Problems of ekstreme duration in open sea saturation exposure. Proccedings of the thirt symposium on underwater physiology. Will. Wilk. Co. Baltimore 98-108, 1967.
  • 5 — BARROWS, E. F., DODDS, H. : Body temperature of mice during anesthesia. Am. J. Physiol. 137 : 259, 1942.
  • 6 — BEHNKE, A. R. : High atmospheric pressures; physiological effects of incereased and decreased pressure, application of these findings to clinical medicine. Ann. Internal Med. 13 2217, 1940.
  • BERTHARION, G. : Toxicité de l'oxygéne hyperbare, effect aigu, étude neurophysiologique. Ann. Chir. Thor. Cardiovasc. 5 : 861, 1966.
  • 8 — BEST, H. C., TAYLOR, B. N. : The Physiological Basis of Medical Practice. Will. Wilk. co. 1966.
  • 9 — BOEREMA, I. : L'oxygénation hyperbarique. Ann. Chir. Thor. Cardiovasc. 5 : 836, 1966.
  • 10 — BRUMMELKAMP, W. H. : Traitement des infections a germes anaerobies par l'inhalation d'oxiygéne en hyperpression. Ann. Chir. Thor. Cardiavasc. 5 : 839, 1966.
  • 11 — DAViDSON, J. K. : Avascular necrosis of bone. Hyperbaric oxygenetion procceding of the second international congress. Livingstone, London, 11, 1965.
  • 12 — DONALD, C. J. : Metabolic depression and oxygen depletion in the diving turtle. J. Appl. Physiol. 24 : 503, 1968.
  • 13 — DONALD, W. K. : Oxygen poisoning. Hyperbaric oxygenation Procee dings of the second international congrees. Livingstone, London, 26 1965.
  • 14 — FOLKOW, B., NILSSON, N. J., YONCE, L. R. : Effects of diving on cardiac autput in ducks. 12. Scandinavian congreess of physiology, Turku, 1966. Acta Physiol. Scand. 68, suppleemntum 277: 51, 1966.
  • 15 — FOSTER, A. C., DAVtDSON, C. 1. : Response to high pressure oxygen of concious valunteers and patints. J. Appl. Physiol. 18 : 492, 1963.
  • 16 — PREJAVILLE, J. P. : Toxicité de l'oxygene - Aspect blochimique. Ann. Chir. Thor. Cardiovac. 5 : 872, 1966.
  • 17 — GELINEO, S. : Adaptation to environment. Hand Book of Physiology, section 4, Washington D. C. 276, 1964.
  • 18 — GILL, B. M., PUGH, G. E. : Basal metabolism and respiration in men living at 5.800 m. (19.000 ft) J. Appl. Phpsiol. 19 : 949, 1964.
  • 19 — GOLDBERGER, E. : A. Primer of Water and Acid-Base Syndromes. Lea and Febiger, Philadelphia, 1965.
  • 20 — GOSSET, C. : Sur la toxicite de l'oxygene. Ann. Chir. Thor. cardiovasc. 5 : 870, 1966.
  • 21 — GAULLON, M., BARDIS, A., NOUAILHAT, F. : L'oxiygénothérapie hyper, bare. La Revue du Prat. 15 : 4397, 1965.
  • 22 — GUYTON, A. C. : Textbook of Medical Physiology. Third edition, W. B. Saunders Co. London, 637, 1966.
  • 23 — HARPER, A. H. : Review of Physiological Chemistry. 11 ed. lange Med. Publ. California. 159, 1967.
  • 24 — HAUGARD, N. : Cellular mechanism of oxygen toxicity. Physiol. Rev. 48 : 311, 1968.
  • 25 — HEMPLEMAN, H. V. : Decompression procedures for deep open sea operation. Proceedings of the Thirt Symposium on Underwater Physiology. Will. Wilk. co. Baltimore, 225, 1967.
  • 26 — HESSER, C. M. : Swedish naval interest in diving research. Proceedings of the Thirt Symposium on Underwater Physiology. Will. Wilk. Co. Baltimore, 16, 1967.
  • 27 — HOVEL, J. : Synthése et perpectives D'avenir (Journées Marseillaises d'Hyperbarie.) Ann. Chir. Thor. Cardiovasc. 5 : 874, 1966.
  • 28 — HUGUENARI), P. : Les Problémes physiques, techniques et biologiques Prosés par l'oxigénothérapie hypperbare. La Presse Med. 75 99, 1967.
  • 29 — HUYBRECHTS, M. : Le PH et sa Mesure. Masson Ed. 273, 1947.
  • 30 — ILLINGWORTH, F. W., LAWSON, 1., LEDINGHAM, 1., SHARP, G. R., GRIFFITHS, J. C. : Surgical and physiological observations in an experimental pressure chamber. Brit. J. Surg. 49 : 222, 1961.
  • 31 — JARRETT, A. S. : Alveolar carbon dioxide tension at increased ambient pressures. J. Appl. Physiol. 21 : 158, 1966.
  • 32 — JOZY, R. : Problémes soulevés dans le domaine de la recherce bilologique par l'utilization des atmosphéres hyperbares et hyperoxygénées. Ann. Chir. Thor. Cardiovac. 5 : 856, 1966.
  • 33 — LAMBERTSEN, C. J. : Proceedings of the Thirt Symposium on UnderWater Physiology. Will. Wilk. co. Baltimore, ix, 223-240, 480, 1967.
  • 34 — LANPHIER, E.H. : Influence of increased ambient pressure upon alveolar ventilation. Proceedings of The Second Symposium on Underwater Physiology. Natl. Acad. Sci., Natl.. Res. Council. Publ. 1181. Washington, 124, 1963.
  • 35 — LANPHIER, E. P., BUSBY, D. E. : Alveolar and PC02 in man under in creased ambient pressures. Proc. 22 intern. Congr. Physiol. Sci. 2: 1962.
  • 36 — LANPHIER, E. H., MORÌN, R.A. : Effects of gas density on carbondioxid elimination. Physiologist, 4: 63, 1961.
  • 37 — LANPHIER, E. H. : Handbook of Physiology. Adaptation to the environment. Section 4, Washington D. C. 893, 1964.
  • 38 — LEDINGHAM, I. M. : Hyperbaric Oxygenation. Livingston, London, 125, 1965.
  • 39 — MALMEJAC, J. : Bases physiologiques du l'utilisation de l'oxygene hyperbare. Ann. Chir. Thor. Cardiovasc, 5 : 827, 1966. 40 — NAIRN, J. R., POWER, G. G., HYDE, W. R., FORSTER, R. E., LAM. BERTSEN, C. J., DICKSON, J. : Diffusing capacity and pulmonary capillary blood flow at hyperbaric pressure. Clin. Invest. 44 : 1591, 1965.
  • 41 — RAYMOND, W. L. : Temperature problemes in multiday exposures to high pressures in the sea. Thermal balance in hyperbaric atmospheres. Proceeding of the Thirt Symposium on Underwater Physiology. Will. Wilk. co. Baltimore. 138, 1967.
  • 42 — SALZANO, J. V., BELL, H. W., WEGLICKI, W. B., SALTZMAN, H. A. : Metabolic, respiratory and hemodynamic responses to exedcise at increased oxygen pressure Procoedings of the Third Symposium on Underwater Physiology. Will. Wilk. Co. Baltimore. 351, 1967.
  • 43 — SCHOLANDER, P. F., HAMMEL, T. T., MESSURIER, H., HEMINGSON, E., GAREY, W. : Circulatory adustment in pearl divers. J. Appl. Physi01. 11: 184, 1962.
  • 44 — SHILLING, C., BENNETT, J. A., HEIM, J. W., THOMSON, R. M., DRINKER, C. H. : Bodily changes and devalopment of pulmonary resistance in rats living under compressed air conditions. J. Exptl. Med. 56: 63, 1932.
  • 45 — SODEMAN, A. W. : Pathologic Physiology. Second Ed. W. B. Saunders co. 289, 1961.
  • 46 — TERZiOÖLU M. : Fizyoloji Ders Kitabl. ismail Akgün Mat. istanbul, 376, 1962.
  • 47 — WHITE, N. F., ROSS, G. : Circulatory changes during experimental di• ving in the turtle. Am. J. Physiol. 211 : 15, 1966.
There are 46 citations in total.

Details

Primary Language English
Subjects Cell Physiology
Journal Section Research Article
Authors

Sema Yavuzer This is me

Publication Date February 28, 1971
IZ https://izlik.org/JA92EZ27SX
Published in Issue Year 1971 Volume: 24 Issue: 1

Cite

APA Yavuzer, S. (1971). Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 24(1), 34-61. https://izlik.org/JA92EZ27SX
AMA 1.Yavuzer S. Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1971;24(1):34-61. https://izlik.org/JA92EZ27SX
Chicago Yavuzer, Sema. 1971. “Yüksek Basıcın Vücut Isısı Ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 24 (1): 34-61. https://izlik.org/JA92EZ27SX.
EndNote Yavuzer S (February 1, 1971) Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi. Ankara Üniversitesi Tıp Fakültesi Mecmuası 24 1 34–61.
IEEE [1]S. Yavuzer, “Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 24, no. 1, pp. 34–61, Feb. 1971, [Online]. Available: https://izlik.org/JA92EZ27SX
ISNAD Yavuzer, Sema. “Yüksek Basıcın Vücut Isısı Ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 24/1 (February 1, 1971): 34-61. https://izlik.org/JA92EZ27SX.
JAMA 1.Yavuzer S. Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1971;24:34–61.
MLA Yavuzer, Sema. “Yüksek Basıcın Vücut Isısı Ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 24, no. 1, Feb. 1971, pp. 34-61, https://izlik.org/JA92EZ27SX.
Vancouver 1.Yavuzer S. Yüksek Basıcın Vücut Isısı ve Kanın Oksido-Redüksiyon Potansiyeline Etkisi. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1971 Feb. 1;24(1):34-61. Available from: https://izlik.org/JA92EZ27SX